Month: October 2022

Hynds, Hannah M.; Lemons, Holli E.; Willis, Jasmine D.; Bell, MarKayla J.; Bottcher, Sydney E.; Dye, Mei Lin N.; Echols, Emily T.; Garner, Edward L.; Hutchinson, Lauren E.; Phillips, Caleb M.; Stephens, Claudia P.; Gilbert, Thomas M.; Wilger, Dale J. published the artcile< Ni-Catalyzed Larock Indenone Annulation with Aliphatic- and Silyl-Substituted Alkynes Supported by Mechanistic Analysis>, Synthetic Route of 6942-39-8, the main research area is nickel catalyzed Larock annulation reaction ortho bromobenzoate alkyne; indenone derivative preparation.

A Ni-catalyzed annulation reaction to synthesize indenones is reported. The reaction provides high yields and regioselectivities when aliphatic- and silyl-substituted alkynes are employed. Both were challenging and underused substrate classes. Several mechanistic observations aided in the development of this reaction, including that β-hydride elimination is turnover-limiting for ortho-halogenated aldehyde substrates and that alkyne dissociation is rate-limiting for internal aliphatic alkynes. The authors anticipate that these methods will be rapidly adopted due to their synthetic ease and inherent versatility. The authors also anticipate that the mechanistic conclusions will inform further reaction development.

Organometallics published new progress about Alkynes Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 6942-39-8 belongs to class bromides-buliding-blocks, and the molecular formula is C8H6BrFO2, Synthetic Route of 6942-39-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jinno, Shunki; Senoo, Takahiro; Mori, Keiji published the artcile< Access to ortho-Hydroxyphenyl Ketimines via Imine Anion-Mediated Smiles Rearrangement>, Computed Properties of 576-83-0, the main research area is phenoxy benzonitrile aryl bromide nucleophilic addition Smiles rearrangement; phenyliminomethyl aryl phenol preparation.

Access to N-(2-halophenyl)-2-hydroxyphenylimine derivatives via imine anion-mediated Smiles rearrangement. When 2-(2-halophenoxy)benzonitriles were treated with 1.2-1.4 equiv of organolithium reagents, nucleophilic addition to the nitrile group followed by Smiles rearrangement occurred to give various N-(2-halophenyl)-2-hydroxyphenylimine derivatives, which are sometimes difficult to synthesize by the conventional acid-promoted condensation reaction between carbonyl compounds and aniline derivatives, in good to excellent chem. yields (up to 91%).

Organic Letters published new progress about Aromatic ethers Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Computed Properties of 576-83-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ahmad, Maha; Gaumont, Annie-Claude; Durandetti, Muriel; Maddaluno, Jacques published the artcile< Direct Syn Addition of Two Silicon Atoms to a CC Triple Bond by Si-Si Bond Activation: Access to Reactive Disilylated Olefins>, Related Products of 81107-97-3, the main research area is syn addition silicon carbon triple bond activation disilylated olefin; stereoselective disilylated heterocycle preparation; crystal structure mol silylalkenyl silicon oxygen heterocycle preparation; cyclization; disilane; heterocycles; palladium; vinylsilane.

A catalytic intramol. silapalladation of alkynes affords, in good yields and stereoselectively, syn-disilylated heterocycles of different chem. structure and size. When applied to silylethers, this reaction leads to vinylic silanols that undergo a rhodium-catalyzed addition to activated olefins, providing the oxa-Heck or oxa-Michael products, depending on the reaction conditions.

Angewandte Chemie, International Edition published new progress about Addition reaction, stereoselective. 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, Related Products of 81107-97-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jin, Cong-Yang; Du, Ji-Yuan; Zeng, Chao; Zhao, Xian-He; Cao, Ye-Xing; Zhang, Xiang-Zhi; Lu, Xin-Yun; Fan, Chun-An published the artcile< Hypervalent iodine(III)-mediated oxidative dearomatizing cyclization of arylamines>, Application In Synthesis of 16426-64-5, the main research area is amido aryl amine iodane mediated oxidative dearomatizing spirocyclization; spiro lactam cyclohexadiene iminium preparation.

An oxidative dearomatizing cyclization of aryl amines promoted by iodobenzene bis(trifluoroacetate) [PhI(CF3CO2)2] was explored, leading to a novel synthetic approach to functionalized spirocyclic building blocks containing a structurally unique dieniminium moiety. This unprecedented methodol., featuring oxidative dearomatization and carbon-carbon bond-forming cyclization, to some extent, not only expands the synthetic potential of hypervalent iodine chem., but also enriches the oxidation chem. of arylamines.

Advanced Synthesis & Catalysis published new progress about Aromatic amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 16426-64-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrNO4, Application In Synthesis of 16426-64-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Perez-Gomez, Marta; Herrera-Ramirez, Piedad; Bautista, Delia; Saura-Llamas, Isabel; Garcia-Lopez, Jose-Antonio published the artcile< Synthesis of Benzofused O- and N-Heterocycles through Cascade Carbopalladation/Cross-Alkylation of Alkynes Involving the C-C Cleavage of Cyclobutanols>, SDS of cas: 81107-97-3, the main research area is palladium catalyzed cascade carbopalladation alkylation alkyne cyclobutanol; benzofuranylvinyl palladium iodide complex preparation crystal structure; mol structure benzofuranylvinyl palladium iodide complex.

The authors report a Pd-catalyzed route to heterocycles bearing a tetrasubstituted alkene fragment. The authors’ approach merges the intramol. carbopalladation of tethered alkynes with an alkylation step produced by the C-C cleavage of cyclobutanol derivatives An alkenyl-Pd(II) intermediate was isolated and characterized by x-ray diffraction studies. The nature of the tethering alkynyl chain influences the E/Z stereochem. of the alkenyl fragment in the functionalized heterocycles.

Organometallics published new progress about Alkylation. 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, SDS of cas: 81107-97-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Banerji, Biswadip; Adhikary, Saswati; Majumder, Leena; Ghosh, Saswati published the artcile< A Green Synthetic Approach towards Polyarylated Oxazoles via Iodine-Catalyzed One-Pot sp3 C-H Functionalization in Water: From Natural Product Synthesis To Photophysical Studies>, Safety of 4-Bromobenzylamine, the main research area is polyaryl oxazole preparation green chem regioselective; primary amine diketone acyloin aerobic oxidative cyclization iodine catalyst.

A ‘green’ methodol. for the convenient synthesis of specific regioisomers of polysubstituted oxazoles through iodine catalyzed, water-mediated, aerobic oxidative C(sp3)-H functionalization of primary amines has been developed. This mild and regioselective domino procedure does not require toxic peroxides, transition metals and organic solvents. The versatility of this methodol. was demonstrated by preparing a natural product, texaline. It is also scalable and has a wide substrate scope. This methodol. opens up a simple avenue for the synthesis of polyarylated oxazoles from various readily available amines as well as 1,2-diketones and acyloins (α-hydroxyl ketones) in moderate to excellent yields. Furthermore, these highly substituted oxazole mols. showed excellent fluorescence properties and thus have enormous potential to be a new type of fluorescent probe for use in medicinal applications and materials science.

Asian Journal of Organic Chemistry published new progress about Diketones, 1,2-diketones Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Shah, Akshara P.; Sharma, Anuj S.; Sharma, Vinay S.; Shimpi, Navinchandra G. published the artcile< Polyacrylonitrile Nanofibers Incorporating Silver-Decorated Graphitic Carbon Nitride for the Visible-Light-Activated Selective Oxidation of Styrene, Benzylic Methylene Groups, and Benzene>, Recommanded Product: 1-Bromo-3-ethylbenzene, the main research area is photooxidation catalyst nanofiber nanocomposite visible light.

A polyacrylonitrile nanofiber (PAN NF) supported silver nanoparticles-graphitic carbon nitride (Ag NPs/g-C3N4) nanoparticles catalyst was fabricated by electrospinning technique. Structural and morphol. studies indicate that the spherical Ag NPs present in the g-C3N4 material were well-dispersed on the surfaces of the PAN NFs or embedded in the PAN NFs without agglomerating. The catalytic potential of PAN/Ag NPs/g-C3N4 NFs was developed for oxidation of organic substrate such as styrene, -CH2 bonded mols., and benzene under visible light. The visible-light-mediated activity of the catalyst could be aided by the photoactive nature of the g-C3N4 surface. PAN/Ag NPs/g-C3N4 NFs show good selectivity toward epoxide with higher conversion (98%) in the case of styrene oxidation Further, ethylbenzene was oxidized to acetophenone with 99% conversion using H2O2. Addnl., the present material also shows excellent C-H oxidation of benzene (99%) into the desired phenol with higher selectivity. PAN/Ag NPs/g-C3N4 NFs possess mesoporous properties with excellent absorptive performance. This hybrid NFs exhibited enhanced activity, excellent stabilization, and recyclability.

ACS Applied Nano Materials published new progress about Electrospinning. 2725-82-8 belongs to class bromides-buliding-blocks, and the molecular formula is C8H9Br, Recommanded Product: 1-Bromo-3-ethylbenzene.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cai, Rongbin; Zhou, Qi; Hou, Tianjiao; Li, Bing; Liu, Yunzhi; Li, Huan; Gao, Yuan; Zhu, Longyi; Luo, Jun published the artcile< Facile construction of the all-bridge-position-functionalized 2,4,6,8-tetraazaadamantane skeleton and conversion of its N-functionalities>, Safety of 4-Bromobenzylamine, the main research area is tetraazaadamantanyl tricyclic preparation.

In this article, an unusual protocol of a “”one-pot”” three-step strategy to build the special all-bridge-position-functionalized tetraazaadamantane skeletons I [R = i-Bu, Bn, CH2-2-furyl, etc.] from 2,2-dipropenyl-1,3-dioxolane via ozonation, hydrogenation with 5% Pd/BaSO4, and condensation of the in-situ generated dial intermediate with primary amines was reported for the first time. Different primary amines were compatible with this process and the corresponding 2,4,6,8-tetraalkyl-2,4,6,8-tetraazaadamantane-9,10-dione bis(ethylene ketals) were achieved in 19-46% yields. The conversion of the N-benzyl group to some other functionalities such as acetyl, benzoyl, nitroso and nitro was also investigated.

Organic Chemistry Frontiers published new progress about Condensation reaction. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Sifeng; Yang, Qingjing; Wang, Jun published the artcile< Copper(II) triflate-catalyzed highly efficient synthesis of N-substituted 1,4-dihydropyridine derivatives via three-component cyclizations of alkynes, amines, and α,β-unsaturated aldehydes>, Reference of 3893-18-3, the main research area is pyridine dihydro preparation; three component reaction alkyne amine unsaturated aldehyde copper catalyst; dihydropyridine preparation.

A copper(II) triflate-catalyzed three-component cyclization of alkynes, amines, and α,β-unsaturated aldehydes was developed to give various 1,4-dihydropyridines in good to high yields. In addition, this efficient and practical protocol proceeded smoothly in gram scale even when the catalytic loading was reduced to 1 mol %.

Tetrahedron Letters published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Reference of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Alhijry, Ibraheem A.; El Sherbini, Ashraf M.; El Sherbini, Tharwat M. published the artcile< Measurement of deviations of transition probability of the neutral silver lines at 827.35 and 768.77 nm using OES-technique>, Synthetic Route of 82-73-5, the main research area is silver transition probability Boltzmann plot OES spectrum.

Boltzmann plot of laser produced plasma spectral emission of two Ag I-spectral lines at 827.35 and 768.77 nm was carried out. Surprisingly, two order of magnitude lower inherent transition probabilities of the two Ag I-spectral lines could be monitored using optical emission spectroscopy OES-technique. Nd: YAG laser at 532 nm and incident intensities varying from 1.76 to 3.14 GW/cm2 was used to induce plasma emission of silver targets. Six Ag I-lines were identified using echelle spectrograph facility at 546.54, 520.9, 827.35, 768.77, 328.06 and 338.28 nm in addition to the Ha-line. Corrections against optically thick plasma spectral line emission were routinely implemented while taking into consideration the sensitivity of spectrograph-ICCD combination. The new measured values of transition probabilities were verified during plasma expansion under different laser incident irradiances.

Journal of Quantitative Spectroscopy & Radiative Transfer published new progress about Absorptivity. 82-73-5 belongs to class bromides-buliding-blocks, and the molecular formula is C8H3BrO3, Synthetic Route of 82-73-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary