Month: October 2022

Filian, Hossein; Ghorbani-Choghamarani, Arash; Tahanpesar, Elham published the artcile< Ni-guanidine@MCM-41 NPs: a new catalyst for the synthesis of 4,4'-(arylmethylene)-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ols) and symmetric di-aryl sulfides>, HPLC of Formula: 401-78-5, the main research area is diaryl sulfide nickel guanidine nanoparticle catalyst.

In this work, the surface of mesoporous MCM-41 was modified with guanidine, and then, Nickel particles have become immobilized on its surface (Ni-guanidine@MCM-41NPs). This heterogeneous catalyst has been identified by various techniques including: low-angle X-ray diffraction, SEM, energy-dispersive X-ray spectroscopy, inductively coupled plasma, thermal gravimetric anal. and N2 adsorption-desorption measurement isotherms, and its catalytic application was studied in the synthesis of 4,4′-(arylmethylene)-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol) derivatives and sym. di-aryl sulfides. The prepared organometallic complex could be isolated, post-reaction, by simple filtration for several consecutive cycles without a notable change in its catalytic activity.

Journal of the Iranian Chemical Society published new progress about Adsorption. 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, HPLC of Formula: 401-78-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Liu, Renjie; Wang, Yixin; Yan, Qiang published the artcile< CO2-Strengthened Double-Cross-Linked Polymer Gels from Frustrated Lewis Pair Networks>, Quality Control of 576-83-0, the main research area is CO2 strengthened polymer frustrated Lewis pair network; carbon dioxide utilization; double cross-linked networks; frustrated Lewis pairs; polymer gels; stimuli responsive materials.

Conventional thermosets consisting of polymer networks with robust and irreversible chem. linkages are incapable of reshaping or reprocessing once formed. In contrast, reversible non-covalent crosslinks can impart structurally flexible and reconfigurable feature to the networks, but at the expense of certain mech. strength. The integration of fixed covalent bonds and noncovalent bonds into these materials can usually attain enhanced mech. properties and meanwhile provide dynamic and adaptable functions, such as responsive and healing ability to external stimuli. Here a double-crosslinked frustrated Lewis pair network (FLPN) is developed through a specific three-component reaction among triarylborane, triarylphosphine, and CO2, which is composed of permanent chem. crosslinks and dynamic CO2 gas-bridged connections. The amount of CO2 added can regulate the d. of supramol. node in such FLPN, so as to control the strength and toughness of the gel material. Moreover, the broken gel can be rapidly healed by CO2 stimulus through the reconstruction of dynamic covalent network. This study will inspire a new way to create gas-based smart materials by incorporating frustrated Lewis pair chem. into traditional gel system.

Macromolecular Rapid Communications published new progress about Fracture toughness. 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Quality Control of 576-83-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Wei; Cha, Xue-Xiang; Reiner, John; Gao, Yuan; Qiao, Hai-Ling; Shen, Jia-Xiang; Chang, Jun-Biao published the artcile< Synthesis and biological activity of n-butylphthalide derivatives>, Computed Properties of 82-73-5, the main research area is butylphthalide derivative preparation vasorelaxant.

A series of n-butylphthalide derivatives were designed and synthesized. The in vitro activities of these compounds were evaluated by a resting tension of isolated rat thoracic aorta ring assay. Compounds I (R = F, Br) were found to be more active than n-butylphthalide.

European Journal of Medicinal Chemistry published new progress about Cardiovascular disease. 82-73-5 belongs to class bromides-buliding-blocks, and the molecular formula is C8H3BrO3, Computed Properties of 82-73-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Boudreau, Marc A.; Ding, Derong; Meisel, Jayda E.; Janardhanan, Jeshina; Spink, Edward; Peng, Zhihong; Qian, Yuanyuan; Yamaguchi, Takao; Testero, Sebastian A.; O’Daniel, Peter I.; Leemans, Erika; Lastochkin, Elena; Song, Wei; Schroeder, Valerie A.; Wolter, William R.; Suckow, Mark A.; Mobashery, Shahriar; Chang, Mayland published the artcile< Structure-Activity Relationship for the Oxadiazole Class of Antibacterials>, Safety of 2-Bromo-4-(trifluoromethyl)phenol, the main research area is structure preparation oxadiazole derivative antibacterial.

A structure-activity relationship (SAR) for the oxadiazole class of antibacterials was evaluated by syntheses of 72 analogs and determination of the minimal-inhibitory concentrations (MICs) against the ESKAPE panel of bacteria. Selected compounds were further evaluated for in vitro toxicity, plasma protein binding, pharmacokinetics (PK), and a mouse model of methicillin-resistant Staphylococcus aureus (MRSA) infection. Oxadiazole 72c shows potent in vitro antibacterial activity, exhibits low clearance, a high volume of distribution, and 41% oral bioavailability, and shows efficacy in mouse models of MRSA infection.

ACS Medicinal Chemistry Letters published new progress about Antibacterial agent resistance. 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, Safety of 2-Bromo-4-(trifluoromethyl)phenol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zheng, Yan-Long; Newman, Stephen G. published the artcile< Nickel-Catalyzed Domino Heck-Type Reactions Using Methyl Esters as Cross-Coupling Electrophiles>, Electric Literature of 17100-65-1, the main research area is nickel catalyst Heck Suzuki Miyaura coupling methyl ester electrophile; cross-coupling; cyclizations; esters; homogeneous catalysis; nickel.

While esters are frequently used as traditional electrophiles in substitution chem., their application in cross-coupling chem. is still in its infancy. Me esters can be used as coupling electrophiles in Ni-catalyzed Heck-type reactions through the challenging cleavage of the C(acyl)-O bond under relatively mild reaction conditions at either 80 or 100°. With the σ-NiII intermediate generated from the insertion of acyl NiII species into the tethered C:C bond, carbonyl-retentive products were formed by domino Heck/Suzuki-Miyaura coupling and Heck/reduction pathways when organoboron and mild hydride nucleophiles were used.

Angewandte Chemie, International Edition published new progress about Cross-coupling reaction. 17100-65-1 belongs to class bromides-buliding-blocks, and the molecular formula is C9H9BrO3, Electric Literature of 17100-65-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Naeim, Mahtab; Naghipour, Ali; Fakhri, Akram; Sayadi, Mohsen published the artcile< Palladium nanoparticles stabilized on the amino acids-functionalized Fe3O4 as the magnetically recoverable nanocatalysts for Heck and Suzuki reactions>, Application In Synthesis of 401-78-5, the main research area is palladium iron oxide nanocatalyst magnetization Heck Suzuki reaction.

Regarding the green chem. goals, well-organized processes for catalyst separation and reuse have drawn much attention in the past few decades. The strategy of magnetic separation offers a convenient approach for recycling catalysts by applying an appropriate magnetic field. In this paper, a palladium nanoparticle-based Catalyst that is stabilized on the glutathione and aspartic acid-functionalized superparamagnetic Fe3O4 nanoparticles has been prepared by an eco-friendly, economical and effective procedure. The catalytic performance of these novels, highly active and recoverable catalysts was investigated under low loading of the supported palladium nanoparticles for Heck and Suzuki reactions. Under optimal reaction conditions, the nanocomposites afford the corresponding products in excellent yield. The catalysts could be easily separated from the reaction system and efficiently recycled for four consecutive runs without a remarkable loss of their activity. The structural and magnetic properties of the catalysts were identified by Fourier transform IR (FT-IR), Powder X-ray diffraction (XRD), SEM (SEM), vibration sample magnetometer (VSM), inductively coupled plasma at. emission anal. (ICP-AES) and thermogravimetric anal. (TGA).

Inorganica Chimica Acta published new progress about Heck reaction. 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, Application In Synthesis of 401-78-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhu, Jun; Zhang, Rui; Dong, Guangbin published the artcile< Orthogonal cross-coupling through intermolecular metathesis of unstrained C(aryl)-C(aryl) single bonds>, Electric Literature of 1530-33-2, the main research area is biaryl ruthenium catalyst regioselective orthogonal cross coupling reaction.

Ruthenium-catalyzed reversible C-C single-bond metathesis reaction that allowed redox- and pH-neutral biaryl synthesis. Assisted by directing groups, unstrained homo-biaryl compounds underwent aryl exchanges to generate cross-biaryl products, catalyzed by a well-defined air-stable ruthenium(II) complex. Functional groups reactive under typical cross-coupling reactions, such as halogen, silyl and boronate moieties, were compatible under the metathesis conditions. Mechanistic studies disclosed an intriguing ‘olefin-metathesis-like’ pathway that involved an unexpected heptacoordinated, 18-electron closed-shell intermediate. The distinct reaction mode discovered here is expected to inspire the development of more general C-C single-bond metathesis and orthogonal cross-coupling reactions.

Nature Chemistry published new progress about Biaryls Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1530-33-2 belongs to class bromides-buliding-blocks, and the molecular formula is C21H22BrP, Electric Literature of 1530-33-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary