Month: October 2022

Koziakov, Denis; Majek, Michal; Jacobi von Wangelin, Axel published the artcile< Radical Aromatic Trifluoromethylthiolation: Photoredox Catalysis vs. Base Mediation>, Safety of (3-Bromophenyl)(trifluoromethyl)sulfane, the main research area is aryl trifluoromethyl sulfide preparation; arenediazonium salt bistrifluoromethyl disulfide photoredox trifluoromethylthiolation.

Trifluoromethyl aryl sulfides (Ar-SCF3) constitute highly attractive building blocks due to their exceptional lipophilicity and chem. properties. Related protocols of radical aromatic trifluoro-methylthiolation of arenediazonium salts were developed that are based on the facile generation of intermediate aryl radicals. Their reactions with com. F3CS-SCF3 under very mild conditions afforded a diverse set of Ar-SCF3 (< 90 % yield). Direct comparison of photoredox catalysis {eosin Y or [Ru(bpy)3]Cl2} with the weak base-mediated dark reaction documented higher synthetic efficiency of the former but higher operational simplicity of the latter strategy. European Journal of Organic Chemistry published new progress about Diazonium compounds, arene, salts Role: RCT (Reactant), RACT (Reactant or Reagent). 2252-45-1 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3S, Safety of (3-Bromophenyl)(trifluoromethyl)sulfane.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Lambright, Alison L.; Liu, Yanyao; Joyner, Isaac A.; Logan, Kaitlyn M.; Brown, M. Kevin published the artcile< Mechanism-Based Design of an Amide-Directed Ni-Catalyzed Arylboration of Cyclopentene Derivatives>, Product Details of C12H16BrNO2, the main research area is borylated cyclopentane amide derivative preparation; crystal structure borylated cyclopentane amide derivative; mol structure borylated cyclopentane amide derivative; amide directed nickel catalyzed diastereoselective arylboration cyclopentene derivative.

A method for amide-directed Ni-catalyzed diastereoselective arylboration of cyclopentenes is disclosed. The reaction allows for the synthesis of sterically congested cyclopentane scaffolds that contain an easily derivatized boronic ester and amide functional handles. The nature of the amide directing group and its influence on the reaction outcome were studied and ultimately reflect a predictably selective reaction based on the solvent and base counterion.

Organic Letters published new progress about Amides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation) (borylated cyclopentene derivatives). 639520-70-0 belongs to class bromides-buliding-blocks, and the molecular formula is C12H16BrNO2, Product Details of C12H16BrNO2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Mousseau, James J.; Vallee, Frederic; Lorion, Melanie M.; Charette, Andre B. published the artcile< Umpolung Direct Arylation Reactions: Facile Process Requiring Only Catalytic Palladium and Substoichiometric Amount of Silver Salts>, Quality Control of 17100-65-1, the main research area is palladium catalyzed umpolung direct arylation aryl halide arene; biaryl preparation umpolung direct arylation palladium catalyst; aryl iodide bromide arene reactant palladium catalyzed direct arylation.

An umpolung direct arylation process is described. The reaction requires only a catalytic amount of Pd(OAc)2 and a substoichiometric amount of silver salts, without any external base or ligand to proceed. The directed oxidative insertion of the transition metal followed by the coupling into the C-H bond of an unactivated arene has surprisingly not yet been reported, despite the clear advantages in the ease of starting material synthesis. The reaction is regioselective with regards to the arene partner, and the role of the acetate and carbonate groups has been elucidated. This methodol. adds to the very few examples of benzene coupling without the inclusion of electron-withdrawing groups to increase acidity.

Journal of the American Chemical Society published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 17100-65-1 belongs to class bromides-buliding-blocks, and the molecular formula is C9H9BrO3, Quality Control of 17100-65-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Furuta, Shohei; Mori, Toshiaki; Yoshigoe, Yusuke; Sekine, Kohei; Kuninobu, Yoichiro published the artcile< Synthesis, structures and photophysical properties of hexacoordinated organosilicon compounds with 2-(2-pyridyl)phenyl groups>, SDS of cas: 401-78-5, the main research area is optimized geometry hexacoordinated pyridylaryl silicon fluoride compound DFT; crystal structure hexacoordinated pyridylaryl silicon fluoride compound; mol structure hexacoordinated pyridylaryl silicon fluoride compound; bromoarylpyridine preparation cyclization silicon chloride.

The authors synthesized novel hexacoordinated organosilicon compounds with two 2-(2-pyridyl)phenyl groups. Single-crystal x-ray structure analyses indicated that Lewis acid-base interactions exist between the Si atom and two N atoms of the pyridine rings, and that hexacoordinated organosilicon compounds have slightly distorted octahedral structures in the solid state. The hexacoordinated organosilicon compounds are stable in air, H2O, heat, acids, and bases. The fluorescent quantum yield increased dramatically and a significant red shift of the maximum fluorescence wavelength was observed with the introduction of amino groups on the 2-(2-pyridyl)phenyl aromatic rings. The fluorescence colors of a hexacoordinated organosilicon compound with two amino groups can be switched by protonation and deprotonation (neutralization) of the amino groups.

Organic & Biomolecular Chemistry published new progress about Crystal structure. 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, SDS of cas: 401-78-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Q B; Chang, L; Ye, F; Luo, Q H; Tao, Y X; Shu, H H published the artcile< Corrigendum to 'Role of spinal cyclooxygenase-2 and prostaglandin E2 in fentanyl-induced hyperalgesia in rats' (Br J Anaesth 2018; 120: 827-35).>, Product Details of C8H3BrO3, the main research area is .

There is no abstract available for this document.

British journal of anaesthesia published new progress about 82-73-5. 82-73-5 belongs to class bromides-buliding-blocks, and the molecular formula is C8H3BrO3, Product Details of C8H3BrO3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhang, Zhipeng; Yu, Yang; Huang, Fei; Yi, Xiangyan; Xu, Yao; He, Yide; Baell, Jonathan B.; Huang, He published the artcile< Catalytic O-H bond insertion reactions using surface modified sewage sludge as a catalyst>, Product Details of C7H4BrF3O, the main research area is diazoester phenol sewage sludge catalyst insertion reaction green chem; phenoxy acetate preparation antitumor antiinflammatory activity cytotoxicity.

The more economical and greener surface modified sewage sludge-derived carbonaceous materials (SW) treated by perchloric acid as a new catalyst for carbene insertion of α-aryl α-diazoacetates into O-H bonds of phenols with good yields and high functional group tolerance was reported. The scope of natural phenols with compelling biol. activity, and successfully afforded the O-H insertion and meta C-H functionalization products was explored. Their structures was confirmed by single-crystal X-ray crystallog. Furthermore, the bioactivities (anti-tumor and anti-inflammatory) of the majority of O-H insertion products were better than those of the natural phenols themselves. The IC50 values indicated that the remarkable compounds I [ R1 = phenyl; R2 = ethyl] (IC50 = 16.80μM) and I [R1 = phenyl; R2 = prop-2-en-1-yl] (IC50 = 16.48μM) had better inhibition for tumor cell A-549 than pos. control DDP (IC50 = 20.62μM). It should be noted that these transformations was provided a new strategy to derive natural products and discover new drugs.

Green Chemistry published new progress about Acetates Role: PAC (Pharmacological Activity), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), RACT (Reactant or Reagent), PREP (Preparation), USES (Uses). 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, Product Details of C7H4BrF3O.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Fei, Nannan; Wei, Qiang; Cao, Liang; Bai, Yongqi; Ji, Honglei; Peng, Ruixiang; Huang, Like; Hao, Shiyou; Ge, Ziyi published the artcile< A symmetric nonpolar blue AIEgen as nondoped fluorescent OLED emitter with low efficiency roll-off>, Electric Literature of 184239-35-8, the main research area is organic light emitting diode aggregation induced emission.

Blue emitters are necessary for achieving full-color displaying OLEDs, however, most blue emitters show low efficiency, short lifetime or serious efficiency roll-off, hindering the development of OLED techniques. In this research, a nonpolar sym. aggregation-induced emission (AIE) emitter was designed and constructed through facile steps, with the triphenylamine-end, anthracene-spacer and tetraphenylethene (TPE)-center. This emitter exhibited good thermal stability and aggregation-enhanced emission (AEE) characteristics, based on which non-doped blue OLED device was readily fabricated with the maximum external quantum efficiency (EQE) of 2.7% and also with no efficiency roll-off even at 1000 cd m-2, indicative of high efficiency and good stability as fluorescent emitter.

Organic Electronics published new progress about Aggregation-induced emission. 184239-35-8 belongs to class bromides-buliding-blocks, and the molecular formula is C26H18Br2, Electric Literature of 184239-35-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Geng, Zhi-Cong; Zhang, Shao-Yun; Li, Nai-Kai; Li, Ning; Chen, Jian; Li, Hai-Yan; Wang, Xing-Wang published the artcile< Organocatalytic Diversity-Oriented Asymmetric Synthesis of Tricyclic Chroman Derivatives>, Application In Synthesis of 3893-18-3, the main research area is diphenylprolinol trimethylsilyl ether catalyst Michael aldol Diels Alder reaction; hydroxyaryloxobutenoate enal aldol Diels Alder reaction; organocatalytic diversity oriented asym synthesis tricyclic chroman derivative.

The tandem oxo-Michael-IED/HDA (inverse-electron-demand hetero-Diels-Alder) and oxo-Michael-IED/HDA-Michael-Aldol condensation transformations between (E)-2-hydroxyaryl-2-oxobut-3-enoate derivatives with enals have been developed in the presence of (S)-diphenylprolinol trimethylsilyl ether as an organocatalyst. Two types of tricyclic chroman derivatives, e.g. I and II, were, resp., obtained, by adjusting the reactant ratio and reaction temperature, in good yields (up to 96%) with excellent enantioselectivities (up to >99%) and good diastereoselectivities (up to >30/1). It should be noted that the divergent chiral chroman derivatives were obtained by successive reaction of (E)-2-hydroxyaryl-2-oxobut-3-enoate derivatives with two different enal substrates in highly catalytic results.

Journal of Organic Chemistry published new progress about Aldol condensation. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application In Synthesis of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary