Month: October 2022

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Quality Control of 6911-87-1.

Li, Kangkang;Li, Jin-Feng;Yin, Bing;Zeng, Fanlong research published 《 Investigation of NNN Pincer Ruthenium(II) Complexes with a Pendant Hydroxyl Group for N-Monomethylation of amines and Nitroarenes by Methanol》, the research content is summarized as follows. A family of air- and moisture-stable NNN pincer ruthenium(II) complexes with a pendant OH were developed, which exhibit unprecedented high reactivity and selectivity in N-monomethylation of amines and nitroarenes using methanol. The study reveals adopting the combination of 1H-pyrazole-1-yl and 3,5-dimethyl-4-hydroxyethyl-1H-pyrazol-1-yl as the two assistant arms of the pyridyl-backbone is a suitable choice. The mechanism study discloses that, during the catalytic cycle, dehydrogenation of methanol to form formaldehyde is a fast and reversible step.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Quality Control of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Safety of (2-Bromophenyl)boronic acid.

Li, Kai;Huang, Shengli;Liu, Tianyu;Jia, Shiqi;Yan, Hailong research published 《 Organocatalytic Asymmetric Dearomatizing Hetero-Diels-Alder Reaction of Nonactivated Arenes》, the research content is summarized as follows. Nonactivated arenes, such as benzene derivatives, are chem. inert due to their intrinsic aromaticity and low polarity. The catalytic asym. dearomatization (CADA, coined by You and co-workers) of the nonactivated arenes represents a formidable challenge. Herein, the authors demonstrate an organocatalytic asym. dearomatizing hetero-Diels-Alder reaction of benzene derivatives The tunable regioselectivity of this strategy allowed delivery of a diversity of stereochem. complex polycyclic compounds, e.g., I, and oxahelicenes, e.g., II, with excellent stereoselectivity. The high complexity and three-dimensionality of the products were crucial for their potential applications in materials science and drug discovery. Mechanistic studies suggested that this reaction proceeded through a chiral tetra-substituted vinylidene ortho-quinone methide (VQM) intermediate, which was extremely active to overcome the loss of aromaticity of benzene derivatives with concomitant chirality transfer.

Safety of (2-Bromophenyl)boronic acid, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide, Electric Literature of 2576-47-8

Li, Jun;Hu, Zu-E.;Yang, Xian-Ling;Zhang, Meng-Qian;Liu, Yan-Hong;Wang, Na;Yu, Xiao-Qi research published 《 Hierarchical Targeted Delivery of Lonidamine and Camptothecin Based on the Ultra-Rapid pH/GSH Response Nanoparticles for Synergistic Chemotherapy》, the research content is summarized as follows. A facile strategy to construct dual-drug delivery nanoparticles (TL-CPT NPs), which possessed higher loading content of CPT and TPP-LND. Notably, TL-CPT NPs showed promising ultrarapid pH/GSH response to release more than 86% of loaded TPP-LND or 93% of loaded CPT in just 2 h. The results showed that the nanoparticles hierarchically delivered CPT and TPP-LND to targeted different organelles without mutual influence benefiting the ultrarapid pH/GSH response to drug release, and further significantly and synergistically induced cell apoptosis and improved chemotherapeutic efficiency in cancer cells.

2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., Electric Literature of 2576-47-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Recommanded Product: 2-Bromoethylamine hydrobromide.

Li, Jie;Liu, Shu-lei;Yi, Qun;Li, Xiang-yuan;Li, Jian-chuan;Shi, Li-juan;Li, Jun research published 《 Effect of poly(ionic liquid)-based metal complexes on catalytic performance of cycloaddition reaction of CO₂ with epichlorohydrin》, the research content is summarized as follows. Based on the metal-coordination interaction between amino functionalized poly(ionic liquid)-NH₂ and Zn²⁺, a poly(ionic liquid)-based metal complex PIL-Zn with Lewis acid-base sites was assembled at room temperature, and its catalytic performance for the reaction of CO₂ and epichlorohydrin to synthesize chloropropylene carbonate was studied. Through the synergistic effect of acid-base sites (Br^–, Zn²⁺), PIL-Zn can effectively catalyze the conversion of CO₂ under the mild conditions (0.1 MPa, 75°C, 24 h) in the absence of solvent and co-catalyst, the conversion of epichlorohydrin and the selectivity of the target product chloropropylene carbonate are 95% and 99% resp., and its catalytic performance keeps well after 5 recycles. PIL-Zn exhibits good application potential in the field of catalytic conversion of CO₂, which provides a new idea for the development of high performance catalyst materials.

2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., Recommanded Product: 2-Bromoethylamine hydrobromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 4224-70-8.

Li, Jianbin;Huang, Chia-Yu;Han, Jing-Tan;Li, Chao-Jun research published 《 Development of a quinolinium/cobaloxime dual photocatalytic system for oxidative C-C cross-couplings via H₂ release》, the research content is summarized as follows. Designing mol. photocatalysts for potent photochem. reactivities ranks among the most challenging but rewarding endeavors in synthetic photochem. Herein, we document a quinoline-based organo-photoredox catalyst, 2,4-bis(4-methoxyphenyl)quinoline (DPQN^2,4-di-OMe), that could be assembled via the facile aldehyde-alkyne-amine (A³) couplings. Unlike the reported photocatalysts, which impart their photoreactivities as covalently linked entities, our mechanistic studies suggested a distinct proton activation mode of DPQN^2,4-di-OMe. Simply upon protonation, DPQN^2,4-di-OMe could reach a highly oxidizing excited state under visible-light irradiation (E*_1/2 = +1.96 V vs a standard calomel electrode, SCE). On this basis, the synergistic merger of DPQN^2,4-di-OMe and cobaloxime formulated an oxidative cross-coupling platform, enabling the Minisci alkylation and various C-C bond-forming reactions with a diverse pool of radical precursors in the absence of chem. oxidants. The catalytic loading of DPQN^2,4-di-OMe could be minimized to 0.025 mol % (TON = 3360), and a polymer-supported photocatalyst, DPQN^2,4-di-OR@PS, was prepared to facilitate catalyst recycling (at a 0.50 mmol % loading and up to five times without significant loss of photosynthetic efficiency).

Synthetic Route of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde.

Li, Heng;Zhu, Yan;Jiang, Cong;Wei, Jia;Liu, Ping;Sun, Peipei research published 《 HOAc catalyzed three-component reaction for the synthesis of 3,3′-(arylmethylene)bis(1H-indoles)》, the research content is summarized as follows. An efficient HOAc catalyzed three-component cyclization and cascade condensation of o-alkynyl anilines with aromatic aldehydes of 2-(arylethynyl)anilines with arylaldehydes was achieved, which leads to the generation of 3,3′-(arylmethylene)bis(1H-indoles) I [R¹ = Ph, 4-MeC₆H₄, 4-FC₆H₄, etc.; R² = 5-Me, 5-Cl, 6-Me, etc.; R³ = Ph, 4-MeC₆H₄, 4-BrC₆H₄, etc.] with good to excellent yields and high regioselectivity under transition-metal-free conditions. Four new C-C and C-N bonds were effectively formed in a one-pot procedure.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C7H15Br.

Li, Hao;Sibley, Christopher D.;Kharel, Yugesh;Huang, Tao;Brown, Anne M.;Wonilowicz, Laura G.;Bevan, David R.;Lynch, Kevin R.;Santos, Webster L. research published 《 Lipophilic tail modifications of 2-(hydroxymethyl)pyrrolidine scaffold reveal dual sphingosine kinase 1 and 2 inhibitors》, the research content is summarized as follows. The sphingosine 1-phosphate (S1P) signaling pathway is an attractive target for pharmacol. manipulation due to its involvement in cancer progression and immune cell chemotaxis. The synthesis of S1P is catalyzed by the action of sphingosine kinase 1 or 2 (SphK1 or SphK2) on sphingosine and ATP. While potent and selective inhibitors of SphK1 or SphK2 have been reported, development of potent dual SphK1/SphK2 inhibitors are still needed. Towards this end, we report the structure-activity relationship profiling of 2-(hydroxymethyl)pyrrolidine-based inhibitors with 22d being the most potent dual SphK1/SphK2 inhibitor (SphK1 Ki = 0.679μM, SphK2 Ki = 0.951μM) reported in this series. 22D inhibited the growth of engineered Saccharomyces cerevisiae and decreased S1P levels in histiocytic lymphoma myeloid cell line (U937 cells), demonstrating inhibition of SphK1 and 2 in vitro. Mol. modeling studies of 22d docked inside the Sph binding pocket of both SphK1 and SphK2 indicate essential hydrogen bond between the 2-(hydroxymethyl)pyrrolidine head to interact with aspartic acid and serine residues near the ATP binding pocket, which provide the basis for dual inhibition. In addition, the dodecyl tail adopts a “J-shape” conformation found in crystal structure of sphingosine bound to SphK1. Collectively, these studies provide insight into the intermol. interactions in the SphK1 and 2 active sites to achieve maximal dual inhibitory activity.

COA of Formula: C7H15Br, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline, Application In Synthesis of 6911-87-1

Li, Gen;Miller, Steven P.;Radosevich, Alexander T. research published 《 P^III/P^V=O-Catalyzed Intermolecular N-N Bond Formation: Cross-Selective Reductive Coupling of Nitroarenes and Anilines》, the research content is summarized as follows. An organophosphorus-catalyzed method for the synthesis of unsym. hydrazines e.g., I by cross-selective intermol. N-N reductive coupling is reported. This method employs a small ring phosphacycle (phosphetane) catalyst II together with hydrosilane as the terminal reductant to drive reductive coupling of nitroarenes e.g., 1-methanesulfonyl-4-nitrobenzene and anilines e.g., 2,3,4,5-tetrahydro-1H-1-benzazepine with good chemoselectivity and functional group tolerance. Mechanistic investigations support an autotandem catalytic reaction cascade in which the organophosphorus catalyst drives two sequential and mechanistically distinct reduction events via P^III/P^V=O cycling in order to furnish the target N-N bond.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Application In Synthesis of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Category: bromides-buliding-blocks.

Li, Gen;Qin, Ziyang;Radosevich, Alexander T. research published 《 P(III)/P(V)-Catalyzed Methylamination of Arylboronic Acids and Esters: Reductive C-N Coupling with Nitromethane as a Methylamine Surrogate》, the research content is summarized as follows. The direct reductive N-arylation of nitromethane by organophosphorus-catalyzed reductive C-N coupling with arylboronic acid derivatives is reported. This method operates by the action of a small ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylphosphetane P-oxide) together with a mild terminal reductant hydrosilane to drive the selective installation of the methylamino group to (hetero)aromatic boronic acids and esters. This method also provides for a unified synthetic approach to isotopically labeled N-methylanilines from various stable isotopologues of nitromethane (i.e., CD₃NO₂, CH₃¹⁵NO₂, and ¹³CH₃NO₂), revealing this easy-to-handle compound as a versatile precursor for the direct installation of the methylamino group.

Category: bromides-buliding-blocks, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Computed Properties of 244205-40-1.

Li, Gen;Qin, Ziyang;Radosevich, Alexander T. research published 《 P(III)/P(V)-Catalyzed Methylamination of Arylboronic Acids and Esters: Reductive C-N Coupling with Nitromethane as a Methylamine Surrogate》, the research content is summarized as follows. The direct reductive N-arylation of nitromethane by organophosphorus-catalyzed reductive C-N coupling with arylboronic acid derivatives is reported. This method operates by the action of a small ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylphosphetane P-oxide) together with a mild terminal reductant hydrosilane to drive the selective installation of the methylamino group to (hetero)aromatic boronic acids and esters. This method also provides for a unified synthetic approach to isotopically labeled N-methylanilines from various stable isotopologues of nitromethane (i.e., CD₃NO₂, CH₃¹⁵NO₂, and ¹³CH₃NO₂), revealing this easy-to-handle compound as a versatile precursor for the direct installation of the methylamino group.

244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Computed Properties of 244205-40-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary