Month: October 2022

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4897-84-1, formula is C5H9BrO2, The most pervasive is the naturally produced bromomethane. Category: bromides-buliding-blocks

Stachel, Shawn J.;Egbertson, Melissa S.;Wai, Jenny;Machacek, Michelle;Toolan, Dawn M.;Swestock, John;Eddins, Donnie M.;Puri, Vanita;McGaughey, Georgia;Su, Hua-Poo;Perlow, Debbie;Wang, Deping;Ma, Lei;Parthasarathy, Gopal;Reid, John C.;Abeywickrema, Pravien D.;Smith, Sean M.;Uslaner, Jason M. research published 《 Indole acids as a novel PDE2 inhibitor chemotype that demonstrate pro-cognitive activity in multiple species》, the research content is summarized as follows. An internal HTS effort identified a novel PDE2 inhibitor series that was subsequently optimized for improved PDE2 activity and off-target selectivity. The optimized lead, compound 4, improved cognitive performance in a rodent novel object recognition task as well as a non-human primate object retrieval task. In addition, co-crystallization studies of close analog of 4 in the PDE2 active site revealed unique binding interactions influencing the high PDE isoform selectivity.

Category: bromides-buliding-blocks, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Related Products of 70-23-5

Srivastava, Nitin;Kishore, Ram research published 《 Cleaner, greener synthesis, characterization, and anticancer evaluation of 2-thioxo-1,3-thiazolanes》, the research content is summarized as follows. An easy, efficient and green method for synthesizing 2-thioxo-1,3-thiazolanes I [R = Et, Bn, CH₂(2-ClC₆H₄), etc.] via reaction of Et 3-bromo-2-oxopropanoate with amines and carbon disulfide at room temperature in the presence of tetrabutylammonium iodide in aqueous medium. The synthesized compounds showed I good in vitro anticancer activity among which compounds such as I [CH₂(2-ClC₆H₄), n-Bn, CH₂(2-ClC₆H₄), 1-naphthylmethyl] which showed exceptional anticancer activity against HeLa, HCT-15, and U-87 MG, resp., could be further assessed for in vivo anticancer activities. This method used cheaper, least toxic and easily available reagents at normal laboratory temperature

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Related Products of 70-23-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Name: 6-Bromohexanoic acid.

Sreedevi, Padincharapad;Nair, Jyothi B.;Joseph, Manu M.;Murali, Vishnu Priya;Suresh, Cherumuttathu H.;Varma, R. Luxmi;Maiti, Kaustabh Kumar research published 《 Dynamic self-assembly of mannosylated-calix[4]arene into micelles for the delivery of hydrophobic drugs》, the research content is summarized as follows. Carbohydrate-lectin interactions and glycol-mol.-driven self-assembly are powerful yet challenging strategies to create supramol. nanostructures for biomedical applications. Herein, we develop a modular approach of micellization with a small mol. mannosylated-calix[4]arene synthetic core, CA₄-Man3, to generate nano-micelles, CA₄-Man3-NPs, which can target cancer cell surface receptors and facilitate the delivery of hydrophobic cargo. The oligomeric nature of the calix[4]arene enables the dynamic self-assembly of calix[4]arene (CA₄), where an amphiphile, functionalized with mannose units (CA-glycoconjugates) in the upper rim and alkylated lower rim, afforded the CA₄-Man3-NPs in a controllable manner. The presence of thiourea units between calixarene and tri-mannose moiety facilitated the formation of a stable core with bidentate hydrogen bonds, which in turn promoted mannose receptor targeted uptake and helped in the intracellular pH-responsive release of antineoplastic doxorubicin (Dox). Physiochem. features including the stability of the nanomicelle could circumvent the undesirable leakage of the cargoes, ensuring maximum therapeutic output with min. off-targeted toxicity. Most importantly, surface-enhanced Raman scattering (SERS) was utilized for the first time to evaluate the critical micelle concentration during the formation, cellular uptake and intracellular drug release. The present study not only provides an architectural design of a new class of organic small mol. nanomicelles but also unveils a robust self-assembly approach that paves the way for the delivery of a wide range of hydrophobic chemotherapeutic drugs.

Name: 6-Bromohexanoic acid, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 823-78-9, formula is C7H6Br2, The most pervasive is the naturally produced bromomethane. Category: bromides-buliding-blocks

Spinck, Martin;Bischoff, Matthias;Lampe, Philipp;Meyer-Almes, Franz-Josef;Sievers, Sonja;Neumann, Heinz research published 《 Discovery of Dihydro-1,4-Benzoxazine Carboxamides as Potent and Highly Selective Inhibitors of Sirtuin-1》, the research content is summarized as follows. Sirtuins are signaling hubs orchestrating the cellular response to various stressors with roles in all major civilization diseases. Sirtuins remove acyl groups from lysine residues of proteins, thereby controlling their activity, turnover, and localization. The seven human sirtuins, SirT1-7, are closely related in structure, hindering the development of specific inhibitors. Screening 170,000 compounds, we identify and optimize SirT1-specific benzoxazine inhibitors, Sosbo, which rival the efficiency and surpass the selectivity of selisistat (EX527). The compounds inhibit the deacetylation of p53 in cultured cells, demonstrating their ability to permeate biol. membranes. Kinetic anal. of inhibition and docking studies reveal that the inhibitors bind to a complex of SirT1 and NAD, similar to selisistat. These new SirT1 inhibitors are valuable alternatives to selisistat in biochem. and cell biol. studies. Their greater selectivity may allow the development of better targeted drugs to combat SirT1 activity in diseases such as cancer, Huntington’s chorea, or anorexia.

Category: bromides-buliding-blocks, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application In Synthesis of 4224-70-8.

Soyekwo, Faizal;Liu, Changkun;Hu, Yunxia research published 《 Crosslinked copolystyrenes based membranes bearing alkylcarboxylated and alkylsulfonated side chains for organic solvent nanofiltration》, the research content is summarized as follows. Polymeric membranes are more practicable to the cost-effective and energy-efficient solvent recovery and mol. separation in solvent mixtures, but the construction of structure-defined chem. stable as well as high permeance polymer membranes for organic solvent nanofiltration (OSN) applications is an important challenge. Herein, we designed and constructed crosslinked block copolystyrene membranes containing flexible alkylcarboxylated and alkylsufonated side chains for high-separation performance in organic media. The flexible side chains anchored on the all-carbon network render the membranes with good dimensional flexibility due to the rational manipulation of the intermol. and intramol. bonding interactions within the crosslinked structured polymer chains. Depending on the crosslinking degree, the resultant membranes exhibited outstanding stability in polar protic solvents, mild polar aprotic solvents (THF, acetonitrile and acetone) and nonpolar solvents. Specifically, the CPS-24% membrane with a cutoff of 380 g mol^-1 showed good ethanol permeance of 4.16 L m^-2 h^-1 bar^-1 and a high-efficient mol. separation (>96%) of a broad range of small mol. weight solutes (organic dye mols., organic building blocks and antibiotics). The membrane also achieved mol. level selectivity of two mols. with a mass difference down to 141 g mol^-1, which is attractive for mol. separation in the chem. and pharmaceutical industry. This work provides a promising strategy to improve selective solvent permeation and separation of organic mols. in OSN membranes by introducing flexible hydrophilic/hydrophobic side chain domains into the main backbone of rigid polymer structures.

Application In Synthesis of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine, Quality Control of 1575-37-7

Sosa, Alexis A.;Palermo, Valeria;Langer, Peter;Luque, Rafael;Romanelli, Gustavo P.;Pizzio, Luis R. research published 《 Tungstophosphoric acid/mesoporous silicas as suitable catalysts in quinoxaline synthesis》, the research content is summarized as follows. Quinoxalines and their derivatives are of great value in the chem. and biol. sciences. These compounds are found in dyes, agrochems., and are used as building blocks of drugs for the treatment of different diseases. Quinoxalines and their derivatives are synthesized by a heterogeneous catalysis procedure that involves the condensation of 1,2-dicarbonyl compounds with aromatic 1,2-diamines in an aprotic organic solvent at low temperature, in the presence of an acid catalyst composed of tungstophosphoric acid immobilized on mesoporous silica nanoparticles. The reaction process is very simple and the catalyst, besides being very active and selective, can be easily isolated from the reaction medium and reused in subsequent reactions without considerable loss of activity. Quinoxalines are obtained in short reaction time with excellent yields and high purity.

Quality Control of 1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Quality Control of 90-59-5.

Soroceanu, Alina;Stiubianu, George T. research published 《 Siloxane matrix molecularweight influences the properties of nanocomposites based on metal complexes and dielectric elastomer》, the research content is summarized as follows. Siloxane-based elastomers are some of the most sought-after materials for the construction of actuators and equipment for energy harvesting devices. This article focuses on changes of the mech. (breaking stress, breaking strain, Young′s modulus) and dielec. properties for elastomers prepared with silicones, induced by the variation of mol. weight of the matrix, with three different silicone polymers having 60,000 g/mol, 150,000 g/mol, and 450,000 g/mol (from GPC measurements). Multiple siloxane elastomers were crosslinked with methyltriacetoxysilane using the sol-gel route. The dielec. permittivity values of the elastomers were also enhanced with two different complex structures containing siloxane bond and 3d transition metals as filler materials for polydimethylsiloxane polymers with various mol. weights The dielec. spectroscopy tests demonstrated a small decrease (5%) for the values of the dielec. permittivity in relation to increased mol. weight of the siloxane polymer, both for samples prepared with pure polymer and for samples with metal complexes. The samples of nanocomposites showed a >50% increase of dielec. permittivity values relative to samples prepared of pure siloxane elastomer. The thermal tests demonstrated that the nanocomposites retained thermal stability similar with samples prepared of pure siloxane elastomer. The behavior under controlled conditions of humidity showed a trend of increased water vapor sorption with increasing mol. weight but an overall hydrophobic stable character of nanocomposites.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., Quality Control of 90-59-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 629-04-9, formula is C7H15Br, The most pervasive is the naturally produced bromomethane. Synthetic Route of 629-04-9

Song, Zongren;Liu, Xueke;Zhang, Hao;Fang, Dawei;Ma, Xiaoxue research published 《 Investigation of physicochemical properties for novel perrhenate ionic liquid and its catalytic application towards epoxidation of olefins》, the research content is summarized as follows. A novel ionic liquid (IL) based on catalytic functional metal rhenium, [Smim][ReO₄] (1-heptyl-3-methyl-imidazolium perrhenate) was synthesized and characterized. D. and surface tension values of the IL were determined at different temperatures, and the volume and surface properties were calculated and discussed, resp. Furthermore, the synthesized ionic liquid [Smim][ReO₄] was used as a green solvent and catalyst for homogeneous catalyzed epoxidation of olefin with urea hydrogen peroxide (UHP) oxidant. The effect of factors of catalyst, oxidant, reaction time, and reaction temperature was discussed. The conversion of cyclohexene and cyclooctene is over 99% at optimum conditions. The IL [Smim][ReO₄] as catalyst and solvent are characterized by high efficiency, long service life and recoverability, which is a better green homogeneous catalyst for epoxidation of olefins.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Synthetic Route of 629-04-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 90-59-5, formula is C7H4Br2O2, The most pervasive is the naturally produced bromomethane. Application of C7H4Br2O2

Song, Zefeng;Jia, Yuping;Zhang, Daizhou;Wang, De research published 《 DMAP Mediated Efficient Construction of Functionalized Chromenes through One-Pot Reaction of para-Quinone Methides with Allenoates》, the research content is summarized as follows. A novel DMAP-mediated Rauhut-Currier/oxa-Michael addition cascade reaction of hydroxylphenyl-substituted para-quinone methide with allenoate was reported for the first time. A series of functionalized chromenes were successfully obtained with moderate to good yields under this one-pot cascade reaction. The chromene products could be easily transformed into different derivatives and a plausible mechanism was proposed to elucidate this novel reaction.

Application of C7H4Br2O2, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Name: (2-Bromophenyl)boronic acid.

Song, Yongjun;Tian, Mingxing;Yu, Renyou;He, Lei research published 《 Through-Space Charge-Transfer Emitters Developed by Fixing the Acceptor for High-Efficiency Thermally Activated Delayed Fluorescence》, the research content is summarized as follows. Through-space charge-transfer (TSCT) emitters have been extensively explored for thermally activated delayed fluorescence (TADF), but arranging various donors and acceptors into rigid cofacial conformations for various efficient TSCT TADF emitters has remained challenging. Here, we report a “fixing acceptor” design to reach various efficient TSCT TADF emitters. By chem. fixing the acceptor (benzophenone) with a rigid spiro-structure and cofacially aligning various donors with the fixed acceptor, a series of efficient TSCT TADF emitters have been developed. Single-crystal structures and theor. calculations have verified closely packed cofacial donor/acceptor conformations and favorable TSCT in the emitters. In doped films, the emitters afford sky blue to yellow TADF emission, with high photoluminescence efficiencies up to 0.92 and reverse intersystem crossing rates up to 1.0 x 10⁶ s^-1. Organic light-emitting diodes using the emitters afford sky blue to yellow electroluminescence with high external quantum efficiencies up to 20.9%. The work opens a new avenue toward a wide variety of efficient TSCT TADF emitters.

Name: (2-Bromophenyl)boronic acid, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary