Month: October 2022

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5445-17-0, formula is C4H7BrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: Methyl 2-bromopropanoate

Sneha, Mahima;Bhattacherjee, Aditi;Lewis-Borrell, Luke;Clark, Ian P.;Orr-Ewing, Andrew J. research published 《 Structure-Dependent Electron Transfer Rates for Dihydrophenazine, Phenoxazine, and Phenothiazine Photoredox Catalysts Employed in Atom Transfer Radical Polymerization》, the research content is summarized as follows. Organic photocatalysts (PCs) are gaining popularity in applications of photoredox catalysis, but few studies have explored their modus operandi. We report a detailed mechanistic investigation of the electron transfer activation step of organocatalyzed atom transfer radical polymerization (O-ATRP) involving electronically excited organic PCs and a radical initiator, Me 2-bromopropionate (MBP). This study compares nine N-aryl modified PCs possessing dihydrophenazine, phenoxazine, or phenothiazine core chromophores. Transient electronic and vibrational absorption spectroscopies over subpicosecond to nanosecond and microsecond time intervals, resp., track spectroscopic signatures of both the reactants and products of photoinduced electron transfer in N,N-dimethylformamide, dichloromethane, and toluene solutions The rate coefficients for electron transfer exhibit a range of values up to ~10¹⁰ M^-1 s^-1 influenced systematically by the PC structures. These rate coefficients are an order of magnitude smaller for catalysts with charge transfer character in their first excited singlet (S₁) or triplet (T₁) states than for photocatalysts with locally excited character. The latter species show nearly diffusion-limited rate coefficients for the electron transfer to MBP. The derived kinetic parameters are used to model the contributions to electron transfer from the S₁ state of each PC for different concentrations of MBP. Comparisons of singlet and triplet reactivity for one of the phenoxazine PCs reveal that the rate coefficient k_ET(T₁) = (2.7 ± 0.3) x 10⁷ M^-1 s^-1 for electron transfer from the T₁ state is 2 orders of magnitude lower than that from the S₁ state, k_ET(S₁) = (2.6 ± 0.4) x 10⁹ M^-1 s^-1. The trends in bimol. electron transfer rate coefficients are accounted for using a modified Marcus theory for dissociative electron transfer.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Recommanded Product: Methyl 2-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Safety of 1-Bromo-3,5-dimethoxybenzene.

Smith, Craig D.;Thompson, Alison research published 《 The Suzuki-Miyaura reaction of BPin-substituted F-BODIPYs with aryl halides》, the research content is summarized as follows. F-BODIPYs substituted with BPin functionality have been coupled to aryl halides using a mild and efficient catalyst system involving Pd₂(dba)₃ and XPhos. The methodol. enables the Suzuki-Miyaura cross-coupling of electron-rich, electron-poor, and sterically encumbered BPin-substituted F-BODIPYs to aryl halides bearing various functional groups, thus presenting an opportunity for the preparation of highly functionalized F-BODIPYs without need for the corresponding aryl moiety to be available in borylated form.

Safety of 1-Bromo-3,5-dimethoxybenzene, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane, Application In Synthesis of 629-04-9

Skolia, Elpida;Gkizis, Petros L.;Nikitas, Nikolaos F.;Kokotos, Christoforos G. research published 《 Photochemical aerobic oxidation of sulfides to sulfoxides: the crucial role of wavelength irradiation》, the research content is summarized as follows. Herein, a novel, sustainable, light-driven protocol was reported for photochem. aerobic oxidation of sulfides to sulfoxides RS(O)R¹ [R = Ph, naphth-2-yl, n-Bu, etc.; R¹ = Me, Et, n-Pr, etc.], where the impact of wavelength irradiation on sulfide aerobic photooxidation was examined In this work, two different low-catalyst loading (0.05-0.5 mol%) protocols, utilizing anthraquinone as the photocatalyst (under CFL lamps or 427 nm irradiation) were developed and a catalyst-free protocol (under 370 nm irradiation) was also assessed. In addition, a broad scope of substrates was tested and extensive mechanistic studies were performed, in order to distinguish the mechanistic pathways that were followed in the different cases of aryl or alkyl sulfide oxidation under different wavelength irradiation Also implemented this protocols toward the oxidation of several intermediates en route to Sulforaphane.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Application In Synthesis of 629-04-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Organobromine compounds have fallen under increased scrutiny for their environmental impact., SDS of cas: 6911-87-1.

Sisco, Edward;Barnes, Korry L. research published 《 Design, Synthesis, and Biological Evaluation of Novel 1,3-Oxazole Sulfonamides as Tubulin Polymerization Inhibitors》, the research content is summarized as follows. A series of novel 1,3-oxazole sulfonamides I (R = 4-FC₆H₄NH₂, -CH₂CH₂SO₂Me, 1-Naph, etc; R’ = H, Me)were constructed and screened for their potential to inhibit cancer cell growth. These compounds were evaluated against the full NCI-60 human tumor cell lines, with the majority exhibiting promising overall growth inhibitory properties. They displayed high specificity within the panel of leukemia cell lines vs. all other lines tested. When examined in the dose-response assay, GI₅₀ values fell within the low micromolar to nanomolar ranges. 1,3-Oxazole sulfonamide I (R = 4-Cl-3-CF₃C₆H₃NH₂, R’ = H) displayed the best average growth inhibition, whereas the 2-chloro-5-methylphenyl and 1-naphthyl substituents on the sulfonamide nitrogen proved to be the most potent leukemia inhibitors with mean GI₅₀ values of 48.8 and 44.7 nM, resp. In vitro tubulin polymerization experiments revealed that this class of compounds effectively binds to tubulin and induces the depolymerization of microtubules within cells.

SDS of cas: 6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Reference of 823-78-9.

Singh, Shikha;Trivedi, Laxmikant;Vasudev, Prema G.;Passarella, Daniele;Negi, Arvind S. research published 《 An efficient merging of DBU/enolate and DBU/benzyl bromide organocycles for the synthesis of alpha benzylated 1-indanone derivatives》, the research content is summarized as follows. The merging of dual organocycles of the bicyclic amidine base 1,8-diazabicyclo[5.4.0]undec-7-en (DBU) was demonstrated for the synthesis of alpha-benzylated 1-indanones. A highly reactive enolate intermediate was formed in the presence of DBU, which reacted with DBU/benzyl bromide salt to afford the product at 50°C temperature This simple and straight forward transformation using safer DBU reagent with easily available substrates and excellent yield provides a better alternative to the previously reported methods that required pyrophoric, costly reagents and high or very low-temperature reaction conditions.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Reference of 823-78-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 4-Bromobenzene-1,2-diamine.

Singh, Pooja S.;Badani, Purav M.;Kamble, Rajesh M. research published 《 Blue-orange emitting carbazole based donor-acceptor derivatives: Synthesis and studies of modulating acceptor unit on opto-electrochemical and theoretical properties》, the research content is summarized as follows. In order to demonstrate an effect of varying acceptor unit on optoelectronic properties of Donor-Acceptor (D-A) assembly, we herein designed and synthesized C-N coupled, carbazole based dyes 1-8 by employing Buchwald-Hartwig coupling amination reaction and fully characterized by spectroscopic methods. Presence of intramol. charge transfer (ICT) transitions (λ_max = 403-467 nm) in absorption spectra of all dyes reminiscent D-A assembly in it and emit in blue-yellow region (λ_emm = 467-565 nm) in solution state with marked pos. solvatochromism. The photophys. studies of some of the dyes in different THF/water mixtures revealed aggregation-induced emission (AIE) feature with the nanoparticles formation, as confirmed by dynamic light scattering (DLS) technique. The HOMO (-5.42 to -5.74 eV) and LUMO (-3.03 to -3.50 eV) energy level of these mols. measured by cyclic voltammetry suggest electron transporting property in it. Further, DFT/TDDFT calculation of dyes, indicate quite comparable theor. and exptl. photophys. and electrochem. data. Moreover, calculated singlet (S₁) and triplet (T₁) excitation energy levels by DFT/B3LYP/6-311 G+(d,p) shows small ΔE_ST value for some dyes and hence called as TADF emitters. Thus obtained all optoelectrochem. properties of dyes propose its potential use in optoelectronic devices and in biosensing.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Recommanded Product: 4-Bromobenzene-1,2-diamine

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 629-04-9.

Singh, Dhandeep;Singh, Nirmal research published 《 Synthesis and Evaluation of 1-hydroxybenzotriazole Derivatives: Dual Inhibitors of Carbonic Anhydrase II and Sodium Hydrogen Exchanger I》, the research content is summarized as follows. Ischemia reperfusion injury is responsible for impaired graft functioning in organ transplants, cerebral dysfunction, ischemic heart diseases, systemic inflammatory response syndrome, gastrointestinal dysfunction, and multiple organ dysfunction syndromes. Intracellular pH is critical for cell survival in ischemia reperfusion injury. Sodium hydrogen exchanger I and carbonic anhydrase II are critical in the regulation of intracellular pH. Inhibition of sodium hydrogen exchanger I and carbonic anhydrase II during reperfusion is found to ameliorate ischemia reperfusion injury sep. An attempt is made to synthesize dual inhibitors of sodium hydrogen exchanger and carbonic anhydrase to have better potential drug mol. in ischemia reperfusion injury treatment. The hydroxybenzotriazole is considered as a central pharmacophore for this dual activity and 12 derivatives are synthesized. All derivatives are tested for sodium hydrogen exchanger I and carbonic anhydrase II inhibitory activity. The tosylate derivative is found to be the most potent derivative with IC₅₀ 158.7 +/= 8.4μM for carbonic anhydrase II and 31.07 +/= 1.06μM for sodium hydrogen exchanger I. Although the potency is less than standard drugs but this is the first report of dual inhibitor of carbonic anhydrase II and sodium hydrogen exchanger.

Application In Synthesis of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Organic compounds having carbon bonded to bromine are called organic bromides. Application of C7H15Br.

Singh, Ankita;Malhotra, Shashwat;Bimal, Devla;Bouchet, Lydia M.;Wedepohl, Stefanie;Calderon, Marcelo;Prasad, Ashok K. research published 《 Synthesis, Self-Assembly, and Biological Activities of Pyrimidine-Based Cationic Amphiphiles》, the research content is summarized as follows. Pyrimidine-based cationic amphiphiles (PCAms), i.e., di-trifluoroacetic acid salts of N1-[1′-(1”,3”-diglycinatoxy-propane-2”-yl)-1′,2′,3′-triazole-4′-yl]methyl-N3-alkylpyrimidines have been synthesized utilizing naturally occurring biocompatible precursors, like glycerol, glycine, and uracil/ thymine in good yields. Synthesized PCAms consist of a hydrophilic head group comprising TFA salt of glyceryl 1,3-diglycinate and hydrophobic tail comprising of C-7 and C-12 N3-alkylated uracil or thymine conjugated via a 4-methylene-1,2,3-triazolyl linker. The physicochem. properties of all PCAms, such as critical aggregation concentration, hydrodynamic diameter, shape, and zeta potential (surface charge) were analyzed. These PCAms were also evaluated for their anti-proliferative and anti-tubercular activities. One of the synthesized PCAm exhibited 4- to 75-fold more activity than first-line anti-tubercular drugs streptomycin and isoniazid, resp., against the multidrug resistant clin. isolate 591 of Mycobacterium tuberculosis.

Application of C7H15Br, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5392-10-9, formula is C9H9BrO3, The most pervasive is the naturally produced bromomethane. Safety of 2-Bromo-4,5-dimethoxybenzaldehyde

Singh, Akansha;Kumar, Ravindra research published 《 Sustainable Passerini-tetrazole three component reaction (PT-3CR): selective synthesis of oxaborol-tetrazoles》, the research content is summarized as follows. A sustainable catalyst- and solvent-free Passerini-tetrazole three component reaction (PT-3CR) has been developed for the selective synthesis of benzoxaborol-tetrazoles for the first time. The synthetic potential of oxaboroles was demonstrated towards various functionalized tetrazoles, which are otherwise difficult to achieve through conventional PT-3CR from aromatic aldehydes/ketones. The reaction features high practicality, broad substrate scope and excellent yields (80-98%). Preliminary results of the asym. PT-3CR are also shown for the synthesis of chiral benzoxaboroles.

Safety of 2-Bromo-4,5-dimethoxybenzaldehyde, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Quality Control of 70-23-5.

Sigalapalli, Dilep Kumar;Kiranmai, Gaddam;Parimala Devi, G.;Tokala, Ramya;Sana, Sravani;Tripura, Chaturvedula;Jadhav, Govinda Shivaji;Kadagathur, Manasa;Shankaraiah, Nagula;Nagesh, Narayana;Babu, Bathini Nagendra;Tangellamudi, Neelima D. research published 《 Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: study of microtubule polymerization inhibition and DNA binding》, the research content is summarized as follows. Towards the development of potential anticancer agents, a new series of imidazo[1,2-a]pyridine-oxadiazole hybrids I [R¹ = H, Me, R² = H; R¹ = Br, R² = Me; R³ = Ph, 4-Me₂NC₆H₄, 3,4,5-(MeO)₃C₆H₂, etc.] was synthesized and evaluated for their in vitro anticancer activity against lung cancer (A549) and prostate cancer (PC-3, DU-145) cell lines. Amongst the compounds tested, the compound I [R¹ = R² = H; R³ = 3,4,5-(MeO)₂C₆H₂; (II)] showed the highest potency on A549 cells with an IC₅₀ value of 2.8 ± 0.02μM. Flow cytometric anal. of A549 cells, treated with the compound II, showed apoptosis induction by annexin-v/PI dual staining assay and the effect of II on different phases of cell cycle was also analyzed. Target based studies demonstrated the inhibition of tubulin polymerization by the compound II at an IC₅₀ value of 3.45 ± 0.51μM and its effective binding with CT-DNA. Further, the mol. modeling studies revealed that II has a prominent binding affinity towards α/β-tubulin receptor with admirable physico-chem. properties.

Quality Control of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary