Month: October 2022

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Computed Properties of 70-23-5

Groendyke, Brian J.;Nabet, Behnam;Mohardt, Mikaela L.;Zhang, Haisheng;Peng, Ke;Koide, Eriko;Coffey, Calvin R.;Che, Jianwei;Scott, David A.;Bass, Adam J.;Gray, Nathanael S. research published ã€?Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitorã€? the research content is summarized as follows. Focal adhesion kinase (FAK) is a tyrosine kinase with prominent roles in protein scaffolding, migration, angiogenesis, and anchorage-independent cell survival and is an attractive target for the development of cancer therapeutics. However, current FAK inhibitors display dual kinase inhibition and/or significant activity on several kinases. Although multi-targeted activity is at times therapeutically advantageous, such behavior can also lead to toxicity and confound chem.-biol. studies. We report a novel series of small mols. based on a tricyclic pyrimidothiazolodiazepinone core that displays both high potency and selectivity for FAK. Structure-activity relationship (SAR) studies explored modifications to the thiazole, diazepinone, and aniline “tail,” which identified lead compound BJG-03-025. BJG-03-025 displays potent biochem. FAK inhibition (IC₅₀ = 20 nM), excellent kinome selectivity, activity in 3D-culture breast and gastric cancer models, and favorable pharmacokinetic properties in mice. BJG-03-025 is a valuable chem. probe for evaluation of FAK-dependent biol.

Computed Properties of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5445-17-0, formula is C4H7BrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: Methyl 2-bromopropanoate

Grenet, Erwann;Geant, Pierre-Yves;Salom-Roig, Xavier J. research published ã€?Crystallization-Induced Diastereomer Transformation of α-Bromo α’-Sulfinyl Ketones. Diastereodivergent Synthesis of (+)-α-Conhydrine and (-)-β-Conhydrineã€? the research content is summarized as follows. Crystallization-Induced Diastereomer Transformation (CIDT) of α-Bromo α’-(R)-sulfinylketones RCH(Br)C(O)CH₂S(O)(CH₃)4-CH₃C₆H₅ (R = Me, cyclohexylmethyl) were reported. This process provides not readily accessible enantiopure stereolabile α-bromoketones, which after diastereoselective carbonyl group reduction lead to the corresponding highly value-added anti and syn-bromohydrins RCH(Br)C(OH)CH₂S(O)(CH₃)4-CH₃C₆H₅ with excellent diastereoselectivities. As an application, a diastereodivergent synthesis of enantiopure hemlock alkaloid (+)-α-conhydrine and its diastereomer (-)-β-conhydrine were also described.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Recommanded Product: Methyl 2-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate, HPLC of Formula: 5445-17-0

Grandes Reyes, Carlos Fitzgerald;Chen, Sung-Po R.;Bobrin, Valentin A.;Jia, Zhongfan;Monteiro, Michael J. research published ã€?Temperature-Induced Formation of Uniform Polymer Nanocubes Directly in Waterã€? the research content is summarized as follows. Conventional self-assembly methods of block copolymers in cosolvents (i.e., usually water and organic solvents) has yet to produce a pure and monodisperse population of nanocubes. The requirement to assemble a nanocube is for the second block to have a high mol. weight However, such high mol. weight block copolymers usually result in the formation of kinetically trapped nanostructures even with the addition of organic cosolvents. Here, we demonstrate the rapid production of well-defined polymer nanocubes directly in water by utilizing the thermoresponsive nature of the second block (with 263 monomer units), in which the block copolymer was fully water-soluble below its lower critical solution temperature (LCST) and would produce a pure population of nanocubes when heated above this temperature Incorporating a pH-responsive monomer in the second block allowed us to control the size of the nanocubes in water with pH and the LCST of the block copolymer. We then used the temperature and pH responsiveness to create an adaptive system that changes morphol. when using a unique fuel. This fuel (H₂O₂ + MnO₂) is highly exothermic, and the solution pH increases with the consumption of H₂O₂. Initially, a nonequilibrium spherical nanostructure formed, which transformed over time into nanocubes, and by controlling the exotherm of the reaction, we controlled the time for this transformation. This block copolymer and the water-only method of self-assembly have provided some insights into designing biomimetic systems that can readily adapt to the environmental conditions.

HPLC of Formula: 5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. COA of Formula: C6H6BBrO2.

Gragert, Maria M.;Tomov, Atanas K.;Bettonville, Serge;Pannier, Gaelle;White, Andrew J. P.;Britovsek, George J. P. research published �Biaryl Group 4 Metal Complexes as Non-Metallocene Catalysts for Polyethylene with Long Chain Branching� the research content is summarized as follows. A series of biaryl Group 4 complexes with a bidentate and a tridentate pincer ligand have been synthesized and characterized. The complexes have been applied as metallocene analogs for the controlled polymerization of ethylene and the copolymerization of ethylene and 1-hexene, with a particular focus on the control of the degree of long chain branching in these polymers.

COA of Formula: C6H6BBrO2, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Recommanded Product: 2-Bromoethylamine hydrobromide.

Gradiski, Matthew V.;Kharat, Ali Nemati;Ong, Maegan S. E.;Lough, Alan J.;Smith, Samantha A. M.;Morris, Robert H. research published ã€?A One-Step Preparation of Tetradentate Ligands with Nitrogen and Phosphorus Donors by Reductive Amination and Representative Iron Complexesã€? the research content is summarized as follows. The synthesis and use of the first examples of unsym., mixed phosphine donor tripodal NPP₂‘ ligands N(CH₂CH₂PR₂)₂(CH₂CH₂PPh₂) are presented. The ligands are synthesized via a convenient, one pot reductive amination using 2-(diphenylphosphino)ethylamine and various substituted phosphonium dimers in order to introduce mixed phosphine donors substituted with P/P’, those being Ph/Cy (2), Ph/ⁱPr (3), Ph/ⁱBu (4), Ph/o-Tol (5), and Ph/p-Tol (6). Addnl., authors have developed the first known synthesis of a sym. tripodal NP₃ ligand N(CH₂CH₂PⁱBu₂)₃ using bench safe ammonium acetate as the lone nitrogen source (7). This new protocol eliminates the use of extremely dangerous nitrogen mustard reagents typically required to synthesize NP₃ ligands. Some of these tetradentate ligands and also P₂NN’ ligands N(CH₂-o-C₅H₄N)(CH₂CH₂PR₂)₂ (P₂NN’-Cy, R = Cy; P₂NN’-Ph, R = Ph) prepared by reductive amination using 2-picolylamine are used in the synthesis and reactions of iron complexes. FeCl₂(P₂NN’-Cy) (8) undergoes single halide abstraction with NaBPh₄ to give the trigonal bipyramidal complex [FeCl(P₂NN’-Cy)][BPh₄] (9). Upon exposure to CO(g), complex 9 readily coordinates CO giving [FeCl(P₂NN’-Cy)(CO)][BPh₄] (10), and further treatment with an excess of NaBH₄ results in formation of the hydride complex [Fe(H)(P₂NN’-Cy)(CO)][BPh₄] (11). Their previously reported complex FeCl₂(P₂NN’-Ph) undergoes double halide abstraction with NaBPh₄ in the presence of the coordinating solvent to give [Fe(NCMe)₂(P₂NN’-Ph)][BPh₄]₂ (12). Ligand 3 can be coordinated to FeCl₂, and upon sequential halide abstraction, treatment with NaBH₄, and exposure to an atm. of dinitrogen, the dinitrogen hydride complex [Fe(H)(NPP₂‘-ⁱPr)(N₂)][BPh₄] (13) is isolated. Sym. NP₃ ligand 7 can also be coordinated to FeCl₂ and, upon exposure to an atm. of CO(g), selectively forms [FeCl(NP₃)(CO)][BPh₄] (14) after salt metathesis with NaBPh₄. Complex 14 can be treated with an excess of NaBH₄ to give the hydride complex [Fe(H)(NP₃)(CO)][BPh₄] (15), which can further be deprotonated/reduced to the Fe(0) complex Fe(NP₃)(CO) (16) upon treatment with an excess of KH. The synthesis of novel unsym. tripodal mixed phosphine donor NPP₂‘ ligands is reported. These are used to synthesize a range of iron complexes. A sym. tripodal NP₃ ligand is made from ammonium acetate and is used to synthesize the first Fe(0) NP₃ complex among others.

Recommanded Product: 2-Bromoethylamine hydrobromide, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,â€?0,â€?5,â€?0-​tetrakis(1-​methylpyridinium-â€?-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,â€?0,â€?5,â€?0-​tetrakis(1-​methylpyridinium-â€?-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Safety of Methyl 4-bromobutanoate.

Govindarajan, Sudhanva R.;Jain, Tanmay;Choi, Jae-Won;Joy, Abraham;Isayeva, Irada;Vorvolakos, Katherine research published ã€?A hydrophilic coumarin-based polyester for ambient-temperature initiator-free 3D printing: Chemistry, rheology and interface formationã€? the research content is summarized as follows. Initiator-free, photocurable, low-toxicity, viscoelastic polymer inks are attractive materials for creating low-modulus 3D-printed elastomeric biomedical constructs. In this work, we describe the synthesis, characterization, and 3D printing/crosslinking of a hydrophilic coumarin-PEG polyester (CPP). The viscoelastic CPP melt can be extruded at room temperature and deposited into layer-by-layer patterns. Upon UV irradiation, the coumarin pendant groups undergo [2 + 2] photocyclization, creating a thermoset network without the use of monomers, photoinitiators or propagating radicals. Voxel-voxel adhesion experiments between crosslinked and uncrosslinked material were performed to examine interfacial dynamics in a native, unperturbed state, and various attempts at 3D printing were made to assess the impact of printing conditions on the ultimate printed structure. Rheol. anal. indicates a transition point where elastic behavior overtakes viscous behavior at increasing shear rate. It is hypothesized that this transition point corresponds with changes in interface formation from “sticky” to “bouncy” behavior in voxel-voxel adhesion and 3D printing processes. Tensile-mode dynamic mech. anal. (DMA) and X-Ray microtomog. (microCT) experiments reveal interfacial defect accumulation that results in deterioration of macroscopic structural and mech. properties.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Safety of Methyl 4-bromobutanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Application of C6H7BrN2.

Gotzmann, Carla;Blacque, Olivier;Fox, Thomas;Alberto, Roger research published ã€?[Re(η⁶-C₆H₅-benzimidazole)₂]⁺ and Derivatives as Dye Mimics; Synthesis, UV Absorption Studies and DFT Calculationsã€? the research content is summarized as follows. Functionalizations of highly oxidation and hydrolysis stable mono-cationic rhenium bis-arene complexes [Re(η⁶-C₆H₆)₂]⁺ are of great interest. We directly built up structural features of the well-known Hoechst Dye on the coordinated arenes as a model for prospective DNA minor groove binding studies. Extensions of the aromatic bis-arene unit with functionalized and derivatized benzimidazole moieties resulted in a deep orange color of the complexes, showing UV/Vis absorption spectra with multiple transition maxima. These have been assigned with support of DFT calculations to gain information about their charge transfer natures. The different transitions of the complexes, which are either intra-ligand, ligand-to-ligand or metal-to-ligand charge transitions, were addnl. compared and discussed with the spectra of the corresponding free ligands.

Application of C6H7BrN2, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 19111-87-6, formula is C18H11Br, Name is 2-Bromotriphenylene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Recommanded Product: 2-Bromotriphenylene.

Gore, P. H.;Kamounah, F. S.;Miri, A. Y. research published ã€?Friedel-Crafts cyanation of some reactive aromatic hydrocarbonsã€? the research content is summarized as follows. C₆H₃Me₃ and 7 condensed aromatic hydrocarbons were directly cyanated using the heterogeneous Friedel-Crafts system CNBr/AlCl₃, giving 32-92% of the corresponding nitriles. With 1 exception the reaction was highly regioselective. E.g., anthracene (I; R = H) gave 92% of the carbonitrile I (R = CN) whereas triphenylene (II; R = R¹ = H) gave 32% carbonitrile II (R = CN, R¹ = H) and 48% II (R = H, R¹ = CN).

19111-87-6, 2-Bromotriphenylene is a useful research compound. Its molecular formula is C18H11Br and its molecular weight is 307.2 g/mol. The purity is usually 95%.
2-Bromotriphenylene is a brominating agent that has the ability to react with sodium carbonate and emit light. The luminescence of 2-bromotriphenylene can be used as an indicator of the degree of dilution, or how much water is present in a solution. It also emits light when it reacts with chloride ions in a reaction solution. 2-Bromotriphenylene can be used as a polymer matrix to form polymeric films, which are then used as catalysts for organic reactions. The luminescence properties of 2-bromotriphenylene make it suitable for use in functional theory experiments. This chemical compound is relatively low cost, and has been shown to have high yield in catalysis., Recommanded Product: 2-Bromotriphenylene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Product Details of C7H8BrN.

Gonzalez-Lainez, Miguel;Jimenez, M. Victoria;Azpiroz, Ramon;Passarelli, Vincenzo;Modrego, F. Javier;Perez-Torrente, Jesus J. research published ã€?N-Methylation of Amines with Methanol Catalyzed by Iridium(I) Complexes Bearing an N,O-Functionalized NHC Ligandã€? the research content is summarized as follows. A set of neutral [IrBr(L₂)(κC-^tBuImCH₂PyCH₂OMe)] and cationic [Ir(L₂)(κ²C,N-^tBuImCH₂PyCH₂OMe)]PF₆ (L₂ = cod, (CO)₂) Ir(I) compounds featuring a flexible lutidine-derived polydentate ligand having NHC and -OMe as donor functions were evaluated as catalyst precursors for the N-methylation of aniline using MeOH both as a reducing agent and a C1 source. The carbonyl complexes are somewhat more active than the related diene compounds with the neutral compound [IrBr(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] being the more active. A range of aromatic primary amines, including heterocyclic amines, were selectively transformed into the corresponding N-methylamino derivatives using this catalyst at a low catalyst loading (0.1 mol %) and substoichiometric amounts of Cs₂CO₃ (half equiv) as a base, in MeOH at 423 K. For aliphatic primary amines, selective N,N-dimethylation was achieved under the same catalytic conditions. The unselective deprotonation of the methylene linkers in [IrBr(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] affords two isomeric neutral complexes featuring a coordinated dearomatized pyridine core, which were converted into [Ir(OMe)(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] upon addition of MeOH. This compound undergoes thermal activation of a C-H bond of the tert-Bu group to give the cyclometalated Ir(I) complex [Ir(CO)₂{κ²C,C-(-CH₂Me₂C-ImCH₂PyCH₂OMe)}] featuring a bidentate C,C-coordinated NHC ligand. Mechanistic studies support a borrowing H mechanism proceeding through Ir(I) intermediates with the methoxo complex as the catalytic active species and the cyclometalated complex as the catalyst resting state. D labeling experiments demonstrated that both species are in equilibrium under catalytic conditions, which is consistent with the exhibited catalytic activity of the cyclometalated complex.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Product Details of C7H8BrN

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C7H4Br2O2.

Gong, Zhimin;Qian, Li;Shao, Shuai;Fan, Bo;Peng, Jianbiao;Lu, Kun;Gao, Shixiang research published ã€?Effects of solvent composition on the synthesis of polydopamine Schiff base Cu complex to activate peroxymonosulfate for methyl-paraben degradationã€? the research content is summarized as follows. Solvent composition plays an important role in the synthesis of metal complex materials, but to date little work on this issue has been reported. Herein, a unique Schiff base Cu complex catalyst (DPDA-Cu-95EtOH) was designed based on polydopamine (PDA) and 3, 5-dibromosalicylaldehyde (DBSA), and the influence of H₂O added during the synthesis process on its catalytic performance towards peroxymonosulfate (PMS) activation was comprehensively investigated. Our results demonstrated that adding a small amount (5%, v:v) of H₂O to the solvent absolute ethanol (EtOH) can greatly increase the Cu loading (from 3.56 at% to 10.30 at%) on the catalyst, which significantly enhanced its catalytic ability, and promoted the removal of MeP for about 4.6 times higher than that synthesized without addition of H₂O. ESR (EPR) and quenching tests revealed that ¹O₂, OH and SO^–₄ were responsible for the degradation of Methyl-paraben (MeP). Moreover, the DPDA-Cu-95EtOH/PMS system not only showed excellent stability and reusability, but also exhibited considerable removal efficiency of MeP in real wastewater. Overall, this study provides new insights into the controllable synthesis of Schiff base metal complex used for the efficient activation of PMS to remove micropollutants in wastewater.

COA of Formula: C7H4Br2O2, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary