A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Electric Literature of 244205-40-1.
Wan, Ruomeng;Buss, Joshua A.;Horak, Kyle T.;Agapie, Theodor research published 《 A hemilabile diphosphine pyridine pincer ligand: σ- and π-binding in molybdenum coordination complexes》, the research content is summarized as follows. Mo compounds supported by a hemilabile pyridine diphosphine pincer ligand were synthesized. The ligand demonstrates variable binding modes, adapting to the electronic and geometric requirements of the metal center. In Mo0 and MoII polycarbonyl complexes, coordination through the σ-donating pyridine nitrogen lone pair is observed Upon oxidative group transfer with anionic azide, a MoIV nitride compound is formed, accompanied by a change in the ancillary ligand binding mode to the pyridine π-system. The σ-coordination was restored by subsequent functionalization of the nitride moiety with either silyl electrophiles or protons. Protonation results in redox disproportionation with concomitant nitride functionalization. Characterization by single crystal x-ray diffraction, NMR, and IR spectroscopy is discussed.
Electric Literature of 244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary