Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Product Details of C6H7BrN2.
Yang, Guang;Xiong, Zhicheng;Nie, Hongsheng;He, Meiqin;Feng, Qiong;Li, Xuan;Huang, Huabin;Wang, Shoucai;Ji, Fanghua;Jiang, Guangbin research published 《 Copper-Catalyzed Divergent C-H Functionalization Reaction of Quinoxalin-2(1H)-ones and Alkynes Controlled by N1-Substituents for the Synthesis of (Z)-Enaminones and Furo[2,3-b]quinoxalines》, the research content is summarized as follows. With control by N1-substituents, switchable divergent C-H functionalization reaction of quinoxalin-2(1H)-ones was achieved for the synthesis of (Z)-enaminones I (R1 = Et, H2C:CHCH2, cyclopropylmethyl, 4-O2NC6H4CH2, etc.; R2 = H, 7-MeO, 6,7-Cl2, etc.; R3 = cyclopropyl, Ph, 2-BrC6H4, 2-thienyl, etc.) and furo[2,3-b]quinoxalines II (R4 = H, 6-F3C, 6-F, 8-Me, 6,7-Me2, etc.; R5 = Ph, 3-BrC6H4, 4-EtOC6H4, etc.) using the combination of copper catalyst and oxidant. This new protocol features mild reaction conditions, readily available materials and broad substrate scope. Gram-scale and mechanistic studies were also investigated. Furthermore, some of the products exhibited excellent antitumor activity against A549, HepG-2, MCF-7 and Hela cells, which were tested by MTT assay.
Product Details of C6H7BrN2, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary