Athira, Ck; Manikandan, Priyadharshini; Kandasamy, Elango; Ramani, Prasanna published an article in 2019, the title of the article was Ionic liquid mediated synthesis of labeled peptide nucleic acid monomer.Safety of 2-(2-Bromoethyl)isoindoline-1,3-dione And the article contains the following content:
We have designed and synthesized phthalimido labeled peptide nucleic acid (PNA) monomer through N-alkylation of α-amino acid ester with N-bromo ethylphthalimide which was facilitated by using ionic liquids The alkylated product was condensed with nucleobase such as thymine-1-acetic acid to get the target compound The labeled-PNA monomer is a new mol. which bears a marker and can be easily prepared in two steps. The experimental process involved the reaction of 2-(2-Bromoethyl)isoindoline-1,3-dione(cas: 574-98-1).Safety of 2-(2-Bromoethyl)isoindoline-1,3-dione
The Article related to peptide nucleic acid phthalimido labeled synthesis ionic liquid marker, amino acid ester alkylation bromo ethylphthalimide thymine acetic acid, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Safety of 2-(2-Bromoethyl)isoindoline-1,3-dione
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary