On January 15, 2021, El-Sayed, W. N.; Alkabli, J.; Althumayri, Khalid; Elshaarawy, Reda F. M.; Ismail, Lamia A. published an article.SDS of cas: 574-98-1 The title of the article was Azomethine-functionalized task-specific ionic liquid for diversion of toxic metal ions in the aqueous environment into pharmacological nominates. And the article contained the following:
By this work, a new azomethine-supported task-specific ionic liquid (ABIIL) was fabricated based on bis-(butylimidazolium hexafluorophosphate) salicylidene Schiff base. The successful formation of ABIIL was confirmed form its microanal. and spectral results. The excellent aqueous-ethanolic solubility coupled with the high chelating capacity of ABIIL enabled it to act as a multifunctional scavenger for removing of Cu(II) and Fe(III) ions from aqueous environments. Not only has that, but also transformed these toxic ions into promising pharmacol. candidates. ABIIL showed an excellent scavenging efficiency, as it can uptake up to 98.9% and 96.7% of Fe(III) and Cu(II) ions, resp., from aqueous-ethanolic effluents. Besides, it could be easily regenerated and reused for six cycles without significant loss in its efficiency. The scavenging outputs (M-ABIIL) exhibited excellent and broad-spectrum antimicrobial activity, with a slight preference toward fungi than bacteria. Fe-ABIIL is the most potent antimicrobial nominate as revealed from its MIC values (μg/mL): 16.8 (C. albicans) < 18.9 (S. aureus) < 19.5 (A. flavus) < 23.1 (E. coli). Addnl., this complex is more cytotoxic (IC50 3.40 ±0.53 μg/mL) than the clin. anticancer drug (Vinblastine, VB) (IC50 3.79 ± 1.01 μg/mL) toward colon cancer cells (HTC116), whereas it is less cytotoxic (IC50 85.66 ± 1.44 μg/mL) than VB (IC50 57.12 ± 1.95 μg/mL) to normal human cells (HeLa). Thus, ABIIL has great potential for removing toxic Cu(II) and Fe(III) ions from aqueous environments, converting them into chemotherapeutic agents. The experimental process involved the reaction of 2-(2-Bromoethyl)isoindoline-1,3-dione(cas: 574-98-1).SDS of cas: 574-98-1
The Article related to azomethine ionic liquid toxic metal ion pharmacol nominate, Placeholder for records without volume info and other aspects.SDS of cas: 574-98-1
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