On April 15, 2020, Sandfort, Frederik; Knecht, Tobias; Pinkert, Tobias; Daniliuc, Constantin G.; Glorius, Frank published an article.Name: 2-(2-Bromoethyl)isoindoline-1,3-dione The title of the article was Site-Selective Thiolation of (Multi)halogenated Heteroarenes. And the article contained the following:
A general and simple strategy for the site-selective thiolation of various pharmaceutically relevant electron-rich heteroarenes with thiols is reported. This mild and reliable photocatalytic protocol enables C-S coupling at the most electron-rich position of the (multi)halogenated substrates, complementing established methodologies. Exptl. and computational studies suggest a radical chain mechanism with the key step being a homolytic aromatic substitution of the heteroaryl halide by an electrophilic thiyl radical, highlighting an underdeveloped reactivity mode. The experimental process involved the reaction of 2-(2-Bromoethyl)isoindoline-1,3-dione(cas: 574-98-1).Name: 2-(2-Bromoethyl)isoindoline-1,3-dione
The Article related to heteroarene thiol site selective thiolation photochem iridium, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Name: 2-(2-Bromoethyl)isoindoline-1,3-dione
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary