《Carbamate as an accelerating group in intermolecular Pauson-Khand reaction》 was published in Tetrahedron Letters in 2020. These research results belong to Asano, Shota; Itto-Nakama, Kaori; Arimoto, Hirokazu. Category: bromides-buliding-blocks The article mentions the following:
The Pauson-Khand reaction (PKR) is a powerful means for the construction of cyclopentenones. However, its applications are limited to the intramol. version of this reaction because poor yield and regioselectivity are often the major problems in intermol. PKR. Herein, it was shown that a carbamate moiety in alkene substrate accelerates this intermol. PKR. The reaction of N-4-dimethylaminophenyl O-allyl carbamate with alkyne-cobalt complex gave cyclopentenones in high yields (up to 90%) and regioselectivity (>9:1). The results came from multiple reactions, including the reaction of 4-Bromobutanoic acid(cas: 2623-87-2Category: bromides-buliding-blocks)
4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary