Granados, Albert; Dhungana, Roshan K.; Sharique, Mohammed; Majhi, Jadab; Molander, Gary A. published an article in Organic Letters. The title of the article was 《From Styrenes to Fluorinated Benzyl Bromides: A Photoinduced Difunctionalization via Atom Transfer Radical Addition》.Application In Synthesis of Ethylbromofluoroacetate The author mentioned the following in the article:
An operationally simple and practical method is disclosed to achieve the difunctionalization of styrenes RCH=CH2 (R = Ph, 2-chlorophenyl, 1-benzothiophen-6-yl, etc.), generating fluorinated benzyl bromides RCH(Br)CH2C(F)(R1)C(O)R2 (R1 = H, F; R2 = OEt, NEt2) via a photoinduced atom transfer radical addition process. The developed method is mild, atom-economical, and cost-effective, employs very low photocatalyst loading (1000 ppm), and is highly compatible with a broad range of functional groups on styrene. The versatility of the fluorinated benzyl bromides is demonstrated through their derivatization to a variety of valuable compounds After reading the article, we found that the author used Ethylbromofluoroacetate(cas: 401-55-8Application In Synthesis of Ethylbromofluoroacetate)
Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.Application In Synthesis of Ethylbromofluoroacetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary