In 2019,Tetrahedron Letters included an article by Wang, Hai-Xia; Li, Wen-Peng; Xia, Chao; Xie, Ming-Sheng; Qu, Gui-Rong; Guo, Hai-Ming. Quality Control of Benzyl 2-bromoacetate. The article was titled 《Enantioselective synthesis of chiral carbocyclic pyrimidine nucleosides via asymmetric cyclopropanation》. The information in the text is summarized as follows:
An efficient method to construct chiral cyclopropyl pyrimidine carbocyclic nucleoside analogs bearing a quaternary center was developed via asym. Michael-initiated cyclopropanation. The axis chirality was observed in cyclopropyl pyrimidine carbocyclic nucleoside analogs for the first time, which was caused by the rotationally restricted N-C bond in N-COPh moiety. Using (DHQD)2AQN as the organocatalyst, diverse cyclopropyl pyrimidine carbocyclic nucleoside analogs were generated in 76-93% yields and 73-96% ee. In addition to this study using Benzyl 2-bromoacetate, there are many other studies that have used Benzyl 2-bromoacetate(cas: 5437-45-6Quality Control of Benzyl 2-bromoacetate) was used in this study.
Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is an aromatic chemical, usually appearing as a clear liquid with a moderate sweet-jasmine fragrance. This compound appears as a component of some of our fragrance blends.Quality Control of Benzyl 2-bromoacetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary