Lv, Xin-Yang published the artcileDihydroquinazolinones as adaptative C(sp3) handles in arylations and alkylations via dual catalytic C-C bond-functionalization, SDS of cas: 143-15-7, the publication is Nature Communications (2022), 13(1), 2394, database is CAplus and MEDLINE.
C-C bond forming cross-couplings are convenient technologies for the construction of functional mols. Consequently, there is continual interest in approaches that can render traditionally inert functionality as cross-coupling partners, included in this are ketones which are widely-available commodity chems. and easy to install synthetic handles. Herein, a dual catalytic strategy that utilizes dihydroquinazolinones derived from ketone congeners as adaptative one-electron handles for forging C(sp3) architectures via α C-C cleavage with aryl and alkyl bromides is reported. This approach is achieved by combining the flexibility and modularity of nickel catalysis with the propensity of photoredox events for generating open-shell reaction intermediates. This method is distinguished by its wide scope and broad application profile–including chem. diversification of advanced intermediates–, providing a catalytic technique complementary to existing C(sp3) cross-coupling reactions that operates within the C-C bond-functionalization arena.
Nature Communications published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, SDS of cas: 143-15-7.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary