Improvement of chemical analysis of antibiotics. IV. Fluorodensitometric determination of polyether antibiotics was written by Asukabe, H.;Sasaki, T.;Harada, K. I.;Suzuki, M.;Oka, H.. And the article was included in Journal of Chromatography in 1984.Computed Properties of C18H11BrO The following contents are mentioned in the article:
A fluorodensitometric determination of the polyether antibiotics, salinomycin [53003-10-4] and monensin [17090-79-8], on silica gel thin-layer plates based on fluorescence labeling of carboxylate with 1-bromoacetylpyrene [80480-15-5] was established. The optimum conditions for producing salinomycin 1-pyrenacyl ester are described. Using Kryptofix 222 [23978-09-8] as a catalyst, the reaction fluorescence yield is significantly higher than that using dicyclohexyl-18-crown-6 [16069-36-6]. There is a linear relationship between the fluorescence intensity and the amount of salinomycin and monensin between 2 and 14 ng and the detection limits are 100 pg. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Computed Properties of C18H11BrO).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C18H11BrO
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary