Synthesis and properties of amphipathic fluorescent dye derived from spiculisporic acid anhydride was written by Ishigami, Yutaka;Gama, Yasuo;Matsuzaki, Sanae. And the article was included in Shikizai Kyokaishi in 1991.Formula: C18H11BrO The following contents are mentioned in the article:
The 1-pyrenecarbonylmethyl ester (I) of spiculisporic acid anhydride was synthesized as an amphipathic fluorescent probe from a microbial biosurfactant. I was synthesized by the reaction of spiculisporic acid anhydride, which was derived from spiculisporic acid, with 1-(bromoacetyl)pyrene. I showed different fluorescent spectra by behaving as “fingerprints” in response to various kinds of hydrophobic environments of solvents, mol. aggregates, and liposomes. I gave different fluorescent patterns in solvents depending on the solubility parameter. Excimer formation of I was accelerated in larger micellar domains of heptaoxyethylene dodecyl ether than in SDS. The dependence of the spectrum on surfactant concentrations was also notable. I was considered to have a larger membrane fluidity in liposomal bilayers than in micelles from the different emitting wavelengths of the resp. excimers in liposomes (511 nm) and micelles (440 or 453 nm). This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Formula: C18H11BrO
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary