Rapid Identification of Bacteria by Membrane-Responsive Aggregation of a Pyrene Derivative was written by Long, Shuangshuang;Miao, Lu;Li, Ruihua;Deng, Fei;Qiao, Qinglong;Liu, Xiaogang;Yan, Aixin;Xu, Zhaochao. And the article was included in ACS Sensors in 2019.Application of 80480-15-5 The following contents are mentioned in the article:
An imidazolium-derived pyrene aggregation was developed to rapidly identify and quantify different bacteria species. When the nonemissive aggregates bound to the anionic bacteria surface, the sensor disassembled to turn on significant fluorescence. At the same time, ratiometric signals between pyrene monomer and excimer emission were controlled by different interactions with various bacteria surfaces. The resulted different fluorescent emission profiles then were obtained as fingerprints for various bacterial species. By converting emission profiles directly into output signals of two channels, fluorescence increase and ratiometric change, a two-dimensional anal. map was generated for bacteria identification. The authors demonstrated that the sensor rapidly identified 10 species of bacteria and 14 clin. isolated multidrug-resistant bacteria, and the authors determined their staining properties (Gram-pos. or Gram-neg.). This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application of 80480-15-5).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 80480-15-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary