Detection of okadaic acid by high-performance liquid chromatography in mussels (Perna perna) captured in the Sepetiba Bay was written by Oliveira, G. M.;Silva, P. P. O.;Rosa, C. A. R.;Bastos, R. A.;Ferreira, V. M.;Rodrigues, E. S.. And the article was included in Alimentaria (Madrid, Spain) in 2005.Formula: C18H11BrO The following contents are mentioned in the article:
Okadaic acid (OA) is one of the main toxins responsible for diarrhea from shellfish poisoning (DSP) in humans. The OA was extracted from hepatopancreas of mussels (Perna perna) collected on the Sepetiba and Mangaratiba beaches in Rio de Janeiro (Brazil), derivatized with 1-(bromoacetyl)pyrene, and analyzed by HPLC with fluorescence detection (HPLC-FLD). The retention time of the AO standard was 18.041 min at 11.27 ng/g and 18.318 min at 26.81 ng/g in samples spiked with equivalent of 20 ng OA/g hepatopancreas tissue. The method allowed better evaluation of the presence of AO in non-spiked extracts The OA retention time for the non-spiked extracts was 17.788 min at 26.55 ng/g in samples from the Sepetiba beach and 18.068 min at 10.14 ng/g in samples from the Mangaratiba beach. The detection limit for OA was 8.1 ng/g hepatopancreas tissue at signal:noise ratio of 3:1. The data indicate the presence of OA in the Perna perna mussels from the Sepetiba and Mangaratiba beaches. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Formula: C18H11BrO
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary