Sorci, Mirco published the artcileVirucidal N95 Respirator Face Masks via Ultrathin Surface-Grafted Quaternary Ammonium Polymer Coatings, HPLC of Formula: 143-15-7, the publication is ACS Applied Materials & Interfaces (2022), 14(22), 25135-25146, database is CAplus and MEDLINE.
N95 respirator face masks serve as effective phys. barriers against airborne virus transmission, especially in a hospital setting. However, conventional filtration media materials, such as nonwoven polypropylene fibers, have no inherent virucidal activity, and thus, the risk of surface contamination increases with wear time. The ability of face masks to protect against infection can be likely improved by incorporating components that deactivate viruses on contact. We present a facile method for covalently attaching antiviral quaternary ammonium polymers to the fiber surfaces of nonwoven polypropylene fabrics that are commonly used as active filtration materials in N95 respirators via UV-initiated grafting of biocidal agents. Here, C12-quaternized benzophenone is simultaneously polymerized and grafted onto melt-blown or spunbond polypropylene fabric using 254 nm UV light. This grafting method generated ultrathin polymer coatings which imparted a permanent cationic charge without grossly changing the fiber morphol. or air resistance across the filter. For melt-blown polypropylene, which comprises the filtration layer of N95 respirator masks, filtration efficiency was neg. impacted from 72.5 to 51.3% for uncoated and coated single-ply samples, resp. Similarly, directly applying the antiviral polymer to full N95 masks decreased the filtration efficiency from 90.4 to 79.8%. This effect was due to the exposure of melt-blown polypropylene to organic solvents used in the coating process. However, N95-level filtration efficiency could be achieved by wearing coated spunbond polypropylene over an N95 mask or by fabricating N95 masks with coated spunbond as the exterior layer. Coated materials demonstrated broad-spectrum antimicrobial activity against several lipid-enveloped viruses and Escherichia coli bacteria. For example, a 4.3-log reduction in infectious MHV-A59 virus and a 3.3-log reduction in infectious SuHV-1 virus after contact with coated filters were observed, although the level of viral deactivation varied significantly depending on the virus strain and protocol for assaying infectivity.
ACS Applied Materials & Interfaces published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C11H10O, HPLC of Formula: 143-15-7.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary