Month: November 2022

Liao, Xudong; Zhou, Yi; Ai, Chengmei; Ye, Cuijiao; Chen, Guanghui; Yan, Zhaohua; Lin, Sen published their research in Tetrahedron Letters in 2021. The article was titled 《SO2F2-mediated oxidation of primary and tertiary amines with 30% aqueous H2O2 solution》.Recommanded Product: 626-40-4 The article contains the following contents:

A highly efficient and selective oxidation of primary and tertiary amines employing SO2F2/H2O2/base system was described. Anilines were converted to the corresponding azoxybenzenes I [R = H, 4-Me, 3-Cl-4-Me, etc.], while primary benzylamines were transformed into nitriles ArC≡N [Ar = Ph, 4-ClC6H4, 4-MeOC6H4, etc.] and secondary benzylamines were rearranged to amides ArNHC(O)R1 [Ar = Ph; R1 = Me, Et]. For tertiary amine substrates quinolines, isoquinolines and pyridines, their oxidation products were the corresponding N-oxides II [R1 = R2 = Me; R3 = Me, Ph], III [R4 = H, 7-Me, 6-NO2; R5 = 2-Me, 3-Me, 4-Me], IV [R6 = H, 8-Cl, 6-Br] and V [R7 = H, 2,6-di-Me, 4-MeO, 2-Br, 4-oxiran-2-yl]. The reaction conditions were very mild and just involve SO2F2, amines, 30% aqueous H2O2 solution, and inorganic base at room temperature One unique advantage was that this oxidation system was just composed of inexpensive inorganic compounds without the use of any metal and organic compounds The results came from multiple reactions, including the reaction of 3,5-Dibromoaniline(cas: 626-40-4Recommanded Product: 626-40-4)

3,5-Dibromoaniline(cas: 626-40-4) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Recommanded Product: 626-40-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Duan, Jingxiang; Xiong, Zongli; Zhou, Yuqiao; Yao, Weijun; Li, Xiaoyi; Zhang, Min; Wang, Zhen published their research in Organic Letters in 2021. The article was titled 《Access to Chiral Chromenones through Organocatalyzed Mannich/Annulation Sequence》.Recommanded Product: Benzyl 2-bromoacetate The article contains the following contents:

An efficient and practical method to access chiral chromenones I (R1 = H, 5-OBn, 6-Cl, 7-OMe, etc.; R2 = H, Me, n-pentyl, 2-phenylethenyl, etc.; R3 = Ph, TMS, cyclohexyl, etc.), II bearing one α-amino stereogenic center in the β position of the carbonyl group was reported. The quinine-derived squaramide could efficiently promote Mannich/cycloketalization/dehydration tandem reactions between 1-(2-hydroxyaryl)-1,3-diketones 2-OH-R4C6H3C(O)CH2C(O)R2 (R4 = H, 5-Cl, 4-OMe, 4-OBn, etc.) and functionalized imines R3CCCH(NHBoc)OEt/R5N(OBoc)CH2COOBn (R5 = Cbz, Boc) generated in situ, providing a wide range of chiral chromenones with propargylamine I or α-amino ester moieties II with good results (54 examples, up to 98% ee). In the experimental materials used by the author, we found Benzyl 2-bromoacetate(cas: 5437-45-6Recommanded Product: Benzyl 2-bromoacetate)

Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is an aromatic chemical, usually appearing as a clear liquid with a moderate sweet-jasmine fragrance. This compound appears as a component of some of our fragrance blends.Recommanded Product: Benzyl 2-bromoacetate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhang, Linfeng; Zheng, Jing; Zou, Wenya; Shu, Yongqi; Yang, Weiran published an article in 2021. The article was titled 《Microwave-Assisted Nickel-Catalyzed Rapid Reductive Coupling of Ethyl 3-iodopropionate to Adipic Acid》, and you may find the article in Catalysis Letters.Application of 539-74-2 The information in the text is summarized as follows:

3-Iodopropionic acid (3-IPA) can be efficiently synthesized from the glycerol derivative glyceric acid (GA), which is a potential biomaterial-based platform mol. In this report, Et 3-iodopropionate was rapidly dimerized to di-Et adipate in a microwave reactor using NiCl2.6H2O as a catalyst, co-catalyzed by Mn and the 1, 10-Phenanthroline monohydrate ligand. Under the optimum reaction conditions, di-Et adipate can be obtained with 84% yield at 90°C in just 5 min. Di-Et adipate was hydrolyzed to obtain the adipic acid (AA) in 89% yield with an acid catalyst. AA is an important chem. and a monomer for producing a wide range of high-performance polymeric substances. This rapid coupling method is also applicable to other alkyl halides. The experimental part of the paper was very detailed, including the reaction process of Ethyl 3-bromopropanoate(cas: 539-74-2Application of 539-74-2)

Ethyl 3-bromopropanoate(cas: 539-74-2) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of 539-74-2 Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Jiaguo; Xiao, Dian; Xie, Fei; Li, Wei; Zhao, Lei; Sun, Wei; Yang, Xiaohong; Zhou, Xinbo published an article in 2021. The article was titled 《Novel antibody-drug conjugate with UV-controlled cleavage mechanism for cytotoxin release》, and you may find the article in Bioorganic Chemistry.Application of 2969-81-5 The information in the text is summarized as follows:

Antibody-drug conjugates (ADCs) are being developed worldwide with the potential to revolutionize current cancer treatment strategies. However, off-target toxicity caused by the instability of linkers remains one of the main issues to be resolved. Developing a novel photocontrol-ADC with good stability and photocontrolled release seemed to be an attractive and practical solution In this study, we designed, for the first time, a novel UV light-controlled ADC by carefully integrating the UV-cleavable o-nitro-benzyl structure into the linker. Our preliminary work indicated that the ADC exhibited good stability and photocontrollability while maintaining a targeting effect similar to that of the naked antibody. Upon irradiation with UV light, the ADC rapidly released free cytotoxins and exerted significant cytotoxicity toward drug-resistant tumor cells. Compared to those of the unirradiated cells, the EC50 values of ADCs increased by up to 50-fold. Furthermore, our research confirmed that the degradation products of unirradiated ADC, Cys-1a, were relatively less toxic, thus potentially reducing the off-target toxicity caused by nonspecific uptake of ADCs. The novel design strategy of UV light-controlled ADCs may provide new perspectives for future research on ADCs and promote the development of photocontrol systems. The experimental part of the paper was very detailed, including the reaction process of Ethyl 4-bromobutyrate(cas: 2969-81-5Application of 2969-81-5)

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Application of 2969-81-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Herr, Patrick; Kerzig, Christoph; Larsen, Christopher B.; Haussinger, Daniel; Wenger, Oliver S. published an article in 2021. The article was titled 《Manganese(I) complexes with metal-to-ligand charge transfer luminescence and photoreactivity》, and you may find the article in Nature Chemistry.Related Products of 14516-54-2 The information in the text is summarized as follows:

Precious metal complexes with the d6 valence electron configuration often exhibit luminescent metal-to-ligand charge transfer (MLCT) excited states, which form the basis for many applications in lighting, sensing, solar cells and synthetic photochem. Iron(II) has received much attention as a possible Earth-abundant alternative, but to date no iron(II) complex has been reported to show MLCT emission upon continuous-wave excitation. Manganese(I) has the same electron configuration as that of iron(II), but until now has typically been overlooked in the search for cheap MLCT luminophores. Here we report that isocyanide chelate ligands give access to air-stable manganese(I) complexes that exhibit MLCT luminescence in solution at room temperature These compounds were successfully used as photosensitizers for energy- and electron-transfer reactions and were shown to promote the photoisomerization of trans-stilbene. The observable electron transfer photoreactivity occurred from the emissive MLCT state, whereas the triplet energy transfer photoreactivity originated from a ligand-centered 3π-π* state. [graphic not available: see fulltext]. In the experiment, the researchers used many compounds, for example, Bromopentacarbonylmanganese(I)(cas: 14516-54-2Related Products of 14516-54-2)

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Related Products of 14516-54-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sun, Qing; Lu, Feng-Hui; Ni, Hong-Gang published an article in 2021. The article was titled 《Microplastic-water partitioning of two states halogenated PAHs: Solute and sol》, and you may find the article in Environmental Research.Formula: C14H8Br2 The information in the text is summarized as follows:

The complex interactions of contaminants with microplastics significantly affect ecol. risk assessments. Studies of the sorption behavior of freely dissolved hydrophobic organic contaminants (HOCs) on microplastics are common. However, concentrations of HOCs in the actual aquatic environment sometimes exceed their water solubility A possible explanation is that a microplastic-sol-water three-phase medium (TPM) is formed in the actual water environment. Both states HOCs (in solute and sol) have the potential to migrate to particles suspended in water. To confirm this view, four kinds of microplastics and eight halogenated polycyclic aromatic hydrocarbons (HPAHs) were selected to examine the partitioning of HPAHs between microplastics and water (sol and solute). Both monolayer and multilayer coverage of HPAHs onto microplastics occurred, and chem. sorption dominated the pseudo-sorption mechanism. The microplastic-water partition ratios of HPAHs (0.12-0.74) were approx. four to five orders of magnitude lower than their corresponding KOW values, suggesting that mechanisms other than sorption were involved. Apparently, the sol HPAHs contributed almost identically large increments to both microplastics and water, and closed the gap. For microplastic-supported HPAHs, the contribution of the sol fraction was more than triple that of the dissolved fraction; the key influencing factor was the water solubility of HPAHs. In the experiment, the researchers used 9,10-Dibromoanthracene(cas: 523-27-3Formula: C14H8Br2)

9,10-Dibromoanthracene(cas: 523-27-3) is synthesized by the bromination of anthracene. The bromination reaction is carried out at room temperature using carbon tetrachloride as a solvent. Using 80-85% anthracene as raw material, adding bromine to react for half an hour, the yield is 83-88%.Formula: C14H8Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xu, Yong-Kai; Meng, Mei-Mei; Xi, Ji-Ming; Wang, Li-Fei; Zhu, Rui; Liu, Xing-Gui; Zhang, Rui; Dong, Wei; Lu, Zhen-Zhong; Zheng, He-Gen; Huang, Wei published an article in 2021. The article was titled 《Mixed matrix membranes containing fluorescent coordination polymers for detecting Cr2O72- with high sensitivity, stability and recyclability》, and you may find the article in Dalton Transactions.Related Products of 523-27-3 The information in the text is summarized as follows:

Three coordination polymers (CPs) were synthesized by using CdII, fluorescent 9,10-di(4-pyridyl)anthracene (dpa), and cyclohexane-1,4-dicarboxylic acid (H2cda), and they are [Cd2(dpa)2(cda)Cl2]n (1), [Cd(dpa)2(cda)]n (2) and [Cd(dpa)(cda)(H2O)]n (3). Both 1 and 2 are fluorescent and contain nonporous layers. 3 is an isomer of 2 and contains a porous diamondoid network. Fluorescent mixed matrix membranes were prepared by dispersing the particles of 1 or 2 within the matrix of polymethyl methacrylate, and showed high sensitivity and selectivity for detecting Cr2O72- in water. Both stability and recyclability of the MMMs were remarkably higher than those of the CP powders. In the experiment, the researchers used many compounds, for example, 9,10-Dibromoanthracene(cas: 523-27-3Related Products of 523-27-3)

9,10-Dibromoanthracene(cas: 523-27-3) is synthesized by the bromination of anthracene. The bromination reaction is carried out at room temperature using carbon tetrachloride as a solvent. Using 80-85% anthracene as raw material, adding bromine to react for half an hour, the yield is 83-88%.Related Products of 523-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ruan, Hang; Guo, Zhongnan; Lin, Jiawei; Liu, Kunjie; Guo, Lingling; Chen, Xin; Zhao, Jing; Liu, Quanlin; Yuan, Wenxia published an article in 2021. The article was titled 《Structure and Optical Properties of Hybrid-Layered-Double Perovskites (C8H20N2)2AgMBr8 (M = In, Sb, and Bi)》, and you may find the article in Inorganic Chemistry.SDS of cas: 13465-09-3 The information in the text is summarized as follows:

The Pb-free hybrid-layered-double perovskites (HLDPs) have been proposed as green and stable semiconducting materials for optoelectronic devices, but the synthesized members are still limited. Here, we report the synthesis of three new HLDPs, (C8H20N2)2AgMBr8 (M = In, Sb, and Bi), by a solution method using 1,4-bis(ammoniomethyl)cyclohexane (C8H20N22+) as the organic spacing cation. All three of these HLDPs show 〈100〉-oriented layered structures with Ag and In/Sb/Bi order arranged in corner-sharing octahedral layers. The first-principle calculations indicate the indirect-gap nature of (C8H20N2)2AgInBr8 and (C8H20N2)2AgSbBr8, while their Bi counterpart shows a direct band gap after considering spin-orbit coupling. The band gaps obtained by diffuse-reflectance spectroscopy are 3.11, 2.60, and 2.70 eV for M = In, Sb, and Bi, resp. (C8H20N2)2AgInBr8 shows a broadband red emission centered at 690 nm, and it is mainly attributed to the self-trapped-excitons mechanism. Our results not only provide a series of new “”Pb-free”” HLDPs with chem. diversity but also help us to further understand the structure-property relationships of HLDP materials. The experimental part of the paper was very detailed, including the reaction process of Indium(III) bromide(cas: 13465-09-3SDS of cas: 13465-09-3)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.SDS of cas: 13465-09-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jiang, Huimin; Yan, Liting; Zhang, Shuo; Zhao, Yanchao; Yang, Xue; Wang, Yameng; Shen, Jianxing; Zhao, Xuebo; Wang, Lianzhou published an article in 2021. The article was titled 《Electrochemical surface restructuring of phosphorus-doped carbon@MoP electrocatalysts for hydrogen evolution》, and you may find the article in Nano-Micro Letters.SDS of cas: 623-24-5 The information in the text is summarized as follows:

The hydrogen evolution reaction (HER) through electrocatalysis is promising for the production of clean hydrogen fuel. However, designing the structure of catalysts, controlling their electronic properties, and manipulating their catalytic sites are a significant challenge in this field. Here, we propose an electrochem. surface restructuring strategy to design synergistically interactive phosphorus-doped carbon@MoP electrocatalysts for the HER. A simple electrochem. cycling method is developed to tune the thickness of the carbon layers that cover on MoP core, which significantly influences HER performance. Exptl. investigations and theor. calculations indicate that the inactive surface carbon layers can be removed through electrochem. cycling, leading to a close bond between the MoP and a few layers of coated graphene. The electrons donated by the MoP core enhance the adhesion and electronegativity of the carbon layers; the neg. charged carbon layers act as an active surface. The electrochem. induced optimization of the surface/interface electronic structures in the electrocatalysts significantly promotes the HER. Using this strategy endows the catalyst with excellent activity in terms of the HER in both acidic and alk. environments (c.d. of 10 mA cm-2 at low overpotentials, of 68 mV in 0.5 M H2SO4 and 67 mV in 1.0 M KOH). The experimental part of the paper was very detailed, including the reaction process of 1,4-Bis(bromomethyl)benzene(cas: 623-24-5SDS of cas: 623-24-5)

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Organobromine compounds are produced naturally by marine creatures (sponges, corals, sea slugs, tunicates, sea fans) and seaweed, plants, fungi, lichen, algae, bacteria, microbes, and some mammals. SDS of cas: 623-24-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Decavoli, Cristina; Boldrini, Chiara L.; Trifiletti, Vanira; Luong, Sally; Fenwick, Oliver; Manfredi, Norberto; Abbotto, Alessandro published an article in 2021. The article was titled 《Dye-catalyst dyads for photoelectrochemical water oxidation based on metal-free sensitizers》, and you may find the article in RSC Advances.Reference of 3,6-Dibromo-9H-carbazole The information in the text is summarized as follows:

Dye-Sensitized Photoelectrochem. Cells (DS-PECs) have been emerging as promising devices for efficient solar-induced water splitting. In DS-PECs, dyes and catalysts for water oxidation and/or reduction are typically two sep. components, thus limiting charge transfer efficiency. A small number of organometallic dyes have been integrated with a catalyst to form an integrated dye-catalyst dyad for photoanodes, but until now no dyads based on metal-free organic dyes have been reported for photoanodes. We herein report the first example of dyad-sensitized photoanodes in DS-PEC water splitting based on metal-free organic dyes and a Ru catalyst. The di-branched donor-π-acceptor dyes carry a donor carbazole moiety which has been functionalized with two different terminal pyridyl ligands in order to coordinate a benchmark Ru complex as a water oxidation catalyst, affording water oxidation dyads. The two dyads have been fully characterized in their optical and electrochem. properties, and XPS has been used to confirm the presence of the catalyst bonded to the dye anchored to the semiconductor anode. The two dyads have been investigated in DS-PEC, showing an excellent faradaic efficiency (88% average across all cells, with a best cell efficiency of 95%), thus triggering new perspectives for the design of efficient mol. dyads based on metal-free dyes for DS-PEC water splitting. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Reference of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Reference of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary