Month: November 2022

In 2019,New Journal of Chemistry included an article by Li, Zhi-Jun; Xue, Hua-Dong; Zhang, Yu-Quan; Hu, Huai-Sheng; Zheng, Xu-Dong. Application of 623-24-5. The article was titled 《Construction of a cationic organic network for highly efficient removal of anionic contaminants from water》. The information in the text is summarized as follows:

Widespread water contamination has become a great threat to human survival, and therefore developing an efficient strategy for decontamination of wastewater is of great significance. Herein, a new cationic organic network (CON-1) has been constructed by a facile method from com. available precursors, 1,4-bis(bromomethyl)benzene (BBMB) and 5,10,15,20-tetra(4-pyridyl)porphyrin (TPP), via a quaternization reaction. After being well characterized, CON-1 was employed as an adsorbent for removal of anionic contaminants in aqueous media. Benifitting from the charged framework and exchangeable counter ions, CON-1 exhibits fast adsorption kinetics and high adsorption capacity towards organic dyes and dichromate. The maximum adsorption capacity for the organic dye orange G and Cr2O72- can reach up to 718 mg g-1 and 293 mg g-1, resp. Moreover, CON-1 displays good stability in the adsorption process, it can be regenerated and it can be reused for several cycles. The facile synthesis, high efficiency, and good stability endow CON-1 with great potential in the purification of wastewater. In the experiment, the researchers used many compounds, for example, 1,4-Bis(bromomethyl)benzene(cas: 623-24-5Application of 623-24-5)

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In contrast, terrestrial plants account only for a few bromine-containing compounds.Application of 623-24-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Nature Communications included an article by Krause, Simon; Evans, Jack D.; Bon, Volodymyr; Senkovska, Irena; Iacomi, Paul; Kolbe, Felicitas; Ehrling, Sebastian; Troschke, Erik; Getzschmann, Juergen; Toebbens, Daniel M.; Franz, Alexandra; Wallacher, Dirk; Yot, Pascal G.; Maurin, Guillaume; Brunner, Eike; Llewellyn, Philip L.; Coudert, Francois-Xavier; Kaskel, Stefan. Reference of 3,6-Dibromo-9H-carbazole. The article was titled 《Towards general network architecture design criteria for negative gas adsorption transitions in ultraporous frameworks》. The information in the text is summarized as follows:

Switchable metal-organic frameworks (MOFs) have been proposed for various energy-related storage and separation applications, but the mechanistic understanding of adsorption-induced switching transitions is still at an early stage. Here we report critical design criteria for neg. gas adsorption (NGA), a counterintuitive feature of pressure amplifying materials, hitherto uniquely observed in a highly porous framework compound (DUT-49). These criteria are derived by analyzing the phys. effects of micromechanics, pore size, interpenetration, adsorption enthalpies, and the pore filling mechanism using advanced in situ X-ray and neutron diffraction, NMR spectroscopy, and calorimetric techniques parallelised to adsorption for a series of six isoreticular networks. Aided by computational modeling, we identify DUT-50 as a new pressure amplifying material featuring distinct NGA transitions upon methane and argon adsorption. In situ neutron diffraction anal. of the methane (CD4) adsorption sites at 111 K supported by grand canonical Monte Carlo simulations reveals a sudden population of the largest mesopore to be the critical filling step initiating structural contraction and NGA. In contrast, interpenetration leads to framework stiffening and specific pore volume reduction, both factors effectively suppressing NGA transitions. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Reference of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Reference of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Organic Letters included an article by Elek, Gabor Zoltan; Koppel, Kaur; Zubrytski, Dzmitry M.; Konrad, Nele; Jarving, Ivar; Lopp, Margus; Kananovich, Dzmitry G.. Computed Properties of C7H13BrO2. The article was titled 《Divergent access to histone deacetylase inhibitory cyclopeptides via a late-stage cyclopropane ring cleavage strategy. Short synthesis of chlamydocin》. The information in the text is summarized as follows:

A unified step-economical strategy for accessing histone deacetylase inhibitory peptides is proposed, based on the late-stage installation of multiple zinc-binding functionalities via the cleavage of the strained cyclopropane ring in the common pluripotent cyclopropanol precursor. The efficacy of the proposed diversity-oriented approach has been validated by short stereoselective synthesis of natural product chlamydocin, containing a challenging-to-install fragment of (2S,9S)-2-amino-8-oxo-9,10-epoxydecanoic acid (Aoe) and a range of its analogs, derivatives of 2-amino-8-oxodecanoic and 2-aminosuberic acids. After reading the article, we found that the author used Ethyl 5-bromovalerate(cas: 14660-52-7Computed Properties of C7H13BrO2)

Ethyl 5-bromovalerate(cas: 14660-52-7) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Computed Properties of C7H13BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Halting hyaluronidase activity with hyaluronan-based nanohydrogels: development of versatile injectable formulations》 were Montanari, E.; Zoratto, N.; Mosca, L.; Cervoni, L.; Lallana, E.; Angelini, R.; Matassa, R.; Coviello, T.; Di Meo, C.; Matricardi, P.. And the article was published in Carbohydrate Polymers in 2019. Category: bromides-buliding-blocks The author mentioned the following in the article:

Hyaluronan (HA) is among the most used biopolymers for viscosupplementation and dermocosmetics. However, the current injectable HA-based formulations present relevant limitations: (I) unmodified HA is quickly degraded by endogenous hyaluronidases (HAase), resulting in short lasting properties; (II) crosslinked HA, although shows enhanced stability against HAase, often contains toxic chem. crosslinkers. As such, herein, we present biocompatible self-assembled hyaluronan-cholesterol nanohydrogels (HA-CH NHs) able to bind to HAase and inhibit the enzyme activity in vitro, more efficiently than currently marketed HA-based crosslinked formulations (e.g. Jonexa). HA-CH NHs inhibit HAase through a mixed mechanism, by which NHs bind to HAase with an affinity constant 7-fold higher than that of native HA. Similar NHs, based on gellan-CH, evidenced no binding to HAase, neither inhibition of the enzyme activity, suggesting this effect might be due to the specific binding of HA-CH to the active site of the enzyme. Therefore, HA-CH NHs were engineered into injectable hybrid HA mixtures or phys. hydrogels, able to halt the enzymic degradation of HA. In addition to this study using 4-Bromobutanoic acid, there are many other studies that have used 4-Bromobutanoic acid(cas: 2623-87-2Category: bromides-buliding-blocks) was used in this study.

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《The development of unimolecular conjugated polymeric micelles for the highly selective detection and recovery of gold from electronic waste》 were Liu, Jilin; Yang, Ting; Hu, Zhiru; Feng, Guodong. And the article was published in New Journal of Chemistry in 2019. Recommanded Product: 2969-81-5 The author mentioned the following in the article:

Gold is a widely used precious metal. In this paper, a novel conjugated polymer is designed and synthesized that can be used to detect and sep. gold from electronic waste with satisfactory sensitivity and selectivity. Therefore, this strategy is of great significance for the recycling of gold resources. In the part of experimental materials, we found many familiar compounds, such as Ethyl 4-bromobutyrate(cas: 2969-81-5Recommanded Product: 2969-81-5)

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Recommanded Product: 2969-81-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Hydrogenation of Alkenes Catalyzed by a Non-pincer Mn Complex》 was published in ChemCatChem in 2020. These research results belong to Rahaman, S. M. Wahidur; Pandey, Dilip K.; Rivada-Wheelaghan, Orestes; Dubey, Abhishek; Fayzullin, Robert R.; Khusnutdinova, Julia R.. Product Details of 14516-54-2 The article mentions the following:

Hydrogenation of substituted styrenes and unactivated aliphatic alkenes by mol. hydrogen has been achieved using a Mn catalyst with a non-pincer, picolylphosphine ligand. This is the second reported example of alkene hydrogenation catalyzed by a Mn complex. Mechanistic studies showed that a Mn hydride formed by H2 activation in the presence of a base is the catalytically active species. Based on exptl. and DFT studies, H2 splitting is proposed to occur via a metal-ligand cooperative pathway involving deprotonation of the CH2 arm of the ligand, leading to pyridine dearomatization. In the experiment, the researchers used many compounds, for example, Bromopentacarbonylmanganese(I)(cas: 14516-54-2Product Details of 14516-54-2)

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Product Details of 14516-54-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Fully renewable limonene-derived polycarbonate as a high-performance alkyd resin》 was published in Polymer International in 2020. These research results belong to Li, Chunliang; Veldhuis, Theo; Reuvers, Bart; Sablong, Rafael J.; Koning, Cor E.. Product Details of 1530-32-1 The article mentions the following:

Limonene-derived polycarbonate-based alkyd resins (ARs) have been prepared by copolymerization of limonene dioxide with CO2, catalyzed by a β-diiminate zinc-bis(trimethylsilyl)amido complex, and subsequent chem. modification with soybean oil fatty acids using triphenylethylphosphonium bromide as the catalyst. This quant. partial modification was realized via epoxy-carboxylic acid chem., affording ARs with higher oil lengths, lower polydispersities and higher glass transition temperatures (Tg) in comparison to a conventional polyester AR based on phthalic acid, multifunctional polyol pentaerythritol and soybean fatty acid. The novel limonene polycarbonate AR and the conventional polyester AR were evaluated as coatings and both the phys. drying (without the presence of the oxidative drying accelerator Borchi Oxy Coat) and chem. curing (with Borchi Oxy Coat) processes of these coatings were monitored by measuring the Koenig hardness and complex modulus development with time. A better performance was obtained for the alkyd paint containing polycarbonates modified with fatty acids (FA-PCs), which showed a faster chem. drying, a higher Koenig hardness and a higher Tg in coating evaluation, demonstrating that the fully renewable FA-PCs are promising resins for alkyd paint applications. The experimental process involved the reaction of Ethyltriphenylphosphonium bromide(cas: 1530-32-1Product Details of 1530-32-1)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Product Details of 1530-32-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Amidoxime-Functionalized Covalent Organic Nanosheets for Sequestration of Uranium In Vivo》 was published in ACS Applied Bio Materials in 2020. These research results belong to Chen, Long; Bai, Ru; Wang, Xiaomei; Zhang, Yijing; He, Linwei; Zhang, Mingxing; Chong, Yu; Chai, Zhifang; Wang, Xiao-Feng; Diwu, Juan. Quality Control of 1,4-Bis(bromomethyl)benzene The article mentions the following:

Finding efficient actinide decorporation agents is crucial for public health and the development of the nuclear industry. The current inventory of decorporation agents is predominately limited to a handful of ligands. In this work, a two-dimensional (2D) covalent organic nanosheet (CON) material was rationally designed and tested for in vivo uranium decorporation. This material is extensively grafted with amidoxime (AO), a classic uranium-recognition ligand, which not only provides selective binding sites for uranyl but also expands the interlayer spacing of CON, making the active sites more accessible. Significantly, the results of in vivo experiments demonstrate that, in both prophylactic and prompt administration groups, CON-AO exhibits a higher excretion ratio of uranium from kidneys than that of ZnNa3-diethylenetriamine pentaacetate (DTPA), while presenting a similar level of cytotoxicity. These results suggest that functionalized CONs may emerge as a promising type of actinide in vivo decorporation agent. In the part of experimental materials, we found many familiar compounds, such as 1,4-Bis(bromomethyl)benzene(cas: 623-24-5Quality Control of 1,4-Bis(bromomethyl)benzene)

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals.Quality Control of 1,4-Bis(bromomethyl)benzene Organobromine compounds have fallen under increased scrutiny for their environmental impact.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Biobased Cycloolefin Polymers: Carvone-Derived Cyclic Conjugated Diene with Reactive exo-Methylene Group for Regioselective and Stereospecific Living Cationic Polymerization》 was published in ACS Macro Letters in 2020. These research results belong to Nishida, Takenori; Satoh, Kotaro; Nagano, Shusaku; Seki, Takahiro; Tamura, Masazumi; Li, Yingai; Tomishige, Keiichi; Kamigaito, Masami. Recommanded Product: 1779-49-3 The article mentions the following:

Carvone, a naturally abundant chiral cyclic α,β-unsaturated carbonyl compound, was chem. transformed into cyclic exo-methylene conjugated dienes. The exo-methylene group had high reactivity in cationic polymerization and was efficiently polymerized in a controlled manner via regioselective 1,4-conjugated additions using initiating systems effective for living cationic polymerization of vinyl ethers. The obtained polymers with 1,3-cyclohexenyl units and tetra-substituted olefins in the main chain showed high glass transition temperatures over 110°C. The chiral monomer underwent stereospecific polymerization to result in polymers with low solubility and weak packing of the rigid main chain in the lamellar layers. The racemic mixture resulted in soluble amorphous polymers, which were subsequently hydrogenated into cycloolefin polymers with enhanced thermal properties. The experimental part of the paper was very detailed, including the reaction process of Methyltriphenylphosphonium bromide(cas: 1779-49-3Recommanded Product: 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Recommanded Product: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Cobalt(I)-Catalyzed Borylation of Unactivated Alkyl Bromides and Chlorides》 was published in Organic Letters in 2020. These research results belong to Verma, Piyush Kumar; Prasad, K. Sujit; Varghese, Dominic; Geetharani, K.. Synthetic Route of C4H7Br The article mentions the following:

A Co-complex-catalyzed borylation of a wide range of alkyl halides with a diboron reagent (B2pin2 or B2neop2) was developed under mild reaction conditions, demonstrating the 1st Co-mediated cross-coupling with alkyl electrophiles. This protocol allows alkyl boronic esters to be accessed from alkyl halides, including alkyl chlorides, which were used rarely as coupling partners. Mechanistic studies reveal the possible involvement of an alkyl radical intermediate in this Co-mediated catalytic cycle. After reading the article, we found that the author used (Bromomethyl)cyclopropane(cas: 7051-34-5Synthetic Route of C4H7Br)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Synthetic Route of C4H7Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary