Month: November 2022

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Reference of 1575-37-7.

Wen, Tiantian;Wang, Mingliang;Gao, Jie;Wang, Lanzhi research published 《 Cerium-enriched magnetic/recyclable dual-acid nanocatalyst for one-pot three-component synthesis of functionalized 1,5-benzodiazepines》, the research content is summarized as follows. Cerium enriched magnetic dual-acid nanocatalyst (CoFe₂O₄@SiO₂@APTES@ATA-CeCl₃) as green and recoverable nanocatalyst was prepared The novel nanocatalyst was characterized by Fourier transform IR spectroscopy (FT-IR), powder X-ray diffraction (XRD), SEM, energy-dispersive X-ray spectroscopy (EDS), inductively coupled plasma at. emission spectrometry (ICP-AES), transmission electron microscopy (TEM), XPS, nitrogen absorption-desorption experiment, and vibrating sample magnetometer (VSM). The dual-acid nanocatalyst was able to efficiently catalyze the synthesis of functionalized 1,5-benzodiazepines following through a three-component domino reaction of various substituted o-phenylenediamine, 1,3-dicarbonyl compounds, and phenylacetaldehyde. The dual-acid sites of Bronsted acid (2-aminoterephthalic acid (ATA)) and Lewis acid (CeCl₃) of the catalysts were determinant features. Furthermore, a plausible catalytic mechanism had been proposed. The dual-acid nanocatalyst could be simply separated and reused without any remarkable decrease within the yield after six runs.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Reference of 1575-37-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C7H4Br2O2.

Wen, Chang;Wu, Chuan;Luo, Ruiqiang;Li, Qinghan;Chen, Feng research published 《 Highly Efficient Synthesis of 2-Substituted Benzo[ b ]furan Derivatives from the Cross-Coupling Reactions of 2-Halobenzo[ b ]furans with Organoalane Reagents》, the research content is summarized as follows. A highly efficient and simple route for the synthesis of benzo[ b]furans was developed by palladium-catalyzed cross-coupling reaction of 2-halobenzo[ b]furans with aryl, alkynyl, and alkylaluminum reagents. Various 2-aryl-, 2-alkynyl-, and 2-alkyl benzo[ b]furans was obtained in 23-97% isolated yields using 2-3 mol% PdCl 2/4-6 mol% XantPhos as the catalyst under mild reaction conditions. The aryls beared electron-donating or electron-withdrawing groups in 2-halobenzo[ b]furans gave products in 40-97% isolated yields. In addition, aluminum reagents containing thienyl, furanyl, trimethylsilanyl, and benzyl groups worked efficiently with 2-halobenzo[ b]furans as well, and three bioactive mols. with benzo[ b]furans skeleton were synthesized. Furthermore, the broad substrates scope and the typical maintenance of vigorous efficiency on gram scale made this protocol a potentially practical method to synthesize benzo[ b]furans. On the basis of the exptl. results, a possible catalytic cycle was proposed.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., COA of Formula: C7H4Br2O2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene, Name: 1-Bromo-3,5-dimethoxybenzene

Weiss, Robin;Aubert, Emmanuel;Groslambert, Loic;Pale, Patrick;Mamane, Victor research published 《 Chalcogen Bonding with Diaryl Ditellurides: Evidence from Solid State and Solution Studies.》, the research content is summarized as follows. The chalcogen bonding (ChB) ability of Te is studied in sym. diaryl ditellurides ArTeTeAr, Ar = Ph, 3,4-(OMe)₂C₆H₃, 3,5-(CF₃)2C₆H₃, 2-CF₃C₆H₄, 3,5-(Cl)₂C₆H₃, 3,5-(t-Bu)₂C₆H₃. Among the two Te σ-holes, the one along the less polarized Te-Te bond was calculated as the more electropos. This counter-intuitive situation is due to the hyperconjugation contribution from Te lone pair to the σ* of the adjacent Te which coincides with σ-hole along the more polarized Te-Ar bond. Diaryl ditellurides showed notable structural features in the solid state as a result of intermol. Te···Te ChB, such as a Te₄ rectangle through dimer aggregation or a triangular Te₃ motif, where one Te interacts with both Te atoms of a neighboring mol. through both its σ-hole and lone pair, in a slightly frustrated geometry. Lewis acidity of diaryl ditellurides was also evaluated by NMR with R₃PO as σ-hole acceptors in different solvents. Thus, ¹²⁵Te NMR allowed monitoring Te···O interaction and delivering association constants (K_a) for 1 : 1 adducts. The highest value of K_a=90 M^-1 was measured for the adduct between diaryl ditellurides bearing CF₃ groups and Et₃PO in cyclohexane. Notably, by using nBu₃PO, Te···O interaction was revealed by ¹⁹F-¹H HOESY showing spatial proximity between CF₃ and CH₃ of nBu₃PO.

Name: 1-Bromo-3,5-dimethoxybenzene, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. SDS of cas: 20469-65-2.

Weiss, Robin;Aubert, Emmanuel;Pale, Patrick;Mamane, Victor research published 《 Chalcogen-Bonding Catalysis with Telluronium Cations》, the research content is summarized as follows. Chalcogen bonding results from non-covalent interactions occurring between electrodeficient chalcogen atoms and Lewis bases. Among the chalcogens, tellurium is the strongest Lewis acid, but Te-based compounds are scarcely used as organocatalysts. For the first time, telluronium cations demonstrated impressive catalytic properties at low loadings in three benchmark reactions: the Friedel-Crafts bromination of anisole, the bromolactonization of ω-unsaturated carboxylic acids and the aza-Diels-Alder between Danishefsky′s diene and imines. The ability of telluronium cations to interact with a Lewis base through chalcogen bonding was demonstrated on the basis of multi-nuclear (¹⁷O, ³¹P, and ¹²⁵Te) NMR anal. and DFT calculations

SDS of cas: 20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide, Application In Synthesis of 2576-47-8

Wei, Zhiping;Zheng, Nan;Wang, Yu;Dong, Xiaoli research published 《 Synthesis and the photocatalytic properties of Bi₂₄O₃₁Br₁₀/BiOBr》, the research content is summarized as follows. Bi₂₄O₃₁Br₁₀/BiOBr photocatalysts were synthesized via hydrothermal methods. The morphol. structure and optical performance of as-prepared photocatalysts were characterized by various techniques including DRS, XRD, SEM, TEM and electrochem. test etc. Photocatalytic activity of Bi₂₄O₃₁Br₁₀/BiOBr photocatalysts were evaluated with the degradation of rhodamine B as model reaction under visible-light irradiation The results indicated that Bi₂₄O₃₁Br₁₀/BiOBr-2 with the mass ratio of Bi₂₄O₃₁Br₁₀and BiOBr of 2:1 exhibited excellent photocatalytic activity. The reaction kinetic constant was 0.240 min^-1, which was 6.5 and 3.0 times higher than that of pristine Bi₂₄O₃₁Br₁₀ (0.037 min^-1) and BiOBr (0.081 min^-1), resp. The degradation rate of 97% could be achieved over Bi₂₄O₃₁Br₁₀/BiOBr-2 within 100 min visible-light irradiation The improved photocatalytic performance was attributed to the higher separation efficiency of photoexcited electron-hole pairs. Bi₂₄O₃₁Br₁₀/BiOBr-2 also exhibited excellent stability and recyclability, which showed excellent photocatalytic performance after five consecutive runs.

Application In Synthesis of 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 20469-65-2, formula is C8H9BrO2, The most pervasive is the naturally produced bromomethane. Safety of 1-Bromo-3,5-dimethoxybenzene

Wei, Wei;Liu, Zhihao;Wu, Xiuli;Gan, Cailing;Su, Xingping;Liu, Hongyao;Que, Hanyun;Zhang, Qianyu;Xue, Qiang;Yue, Lin;Yu, Luoting;Ye, Tinghong research published 《 Synthesis and biological evaluation of indazole derivatives as anti-cancer agents》, the research content is summarized as follows. Design, synthesis and biol. evaluation of a series of indazole derivatives I [R¹ = 2-aminopyrimidin-4-yl, 6-amino-3-pyridyl, 4-(4-methylpiperazin-1-yl)phenyl, etc.] was reported. In vitro antiproliferative activity screening showed that compound I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] had potent growth inhibitory activity against several cancer cell lines (IC₅₀ = 0.23-1.15μM). Treatment of the breast cancer cell line 4T1 with compound I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] inhibited cell proliferation and colony formation. I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] dose-dependently promoted the apoptosis of 4T1 cells, which was connected with the upregulation of cleaved caspase-3 and Bax, and down-regulation of Bcl-2. compound I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] also decreased the mitochondrial membrane potential and increased the levels of reactive oxygen species (ROS) in 4T1 cells. Addnl., treatment with compound I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] disrupted 4T1 cells migration and invasion, and the reduction of matrix metalloproteinase metalloproteinase-9 (MMP9) and increase of tissue inhibitor matrix metalloproteinase 2 (TIMP2) were also observed Moreover, compound I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] could suppress the growth of the 4T1 tumor model without obvious side effects in vivo. Taken together, these results identified compound I [R¹ = 6-(4-methylpiperazin-1-yl)-3-pyridyl] as a potential small mol. anti-cancer agent.

Safety of 1-Bromo-3,5-dimethoxybenzene, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4897-84-1, formula is C5H9BrO2, The most pervasive is the naturally produced bromomethane. Synthetic Route of 4897-84-1

Wei, Mingming;Xie, Maodun;Zhang, Zhen;Wei, Yujiao;Zhang, Juan;Pan, Hongli;Li, Benlong;Wang, Jingjing;Song, Yang;Chong, Chuangke;Zhao, Rui;Wang, Jiefu;Yu, Li;Yang, Guang;Yang, Cheng research published 《 Design and synthesis of novel Flavone-based histone deacetylase inhibitors antagonizing activation of STAT3 in breast cancer》, the research content is summarized as follows. In this study, a class of novel HDACs inhibitors I (R = H, 4-CH₃OC₆H₄; R¹ = H, C₆H₅, 4-CH₃OC₆H₄, 4-OHC₆H₄; R² = H, OH; X = (CH₂)_n, n = 1, 3, 4, 5, 6, 7), II•HCl (R³ = N(CH₃)₂, 4-methylpiperazin-1-yl, morpholin-4-yl, piperidin-1-yl, pyrrolidin-1-yl; Y = (CH₂)_n, n = 5, 6, 7; Z = (CH₂)_n, n = 2, 3) was designed and synthesized based on the structure of flavones and isoflavones, followed by biol. evaluation. To be specific, a lead compound II•HCl [R³ = N(CH₃)₂; Y = (CH₂)₅; Z = (CH₂)₂ (III)] was discovered with strong anti-proliferative effects on a variety of solid tumor cells, especially for breast cancer cells with resistance to SAHA. Studies demonstrated that III could significantly inhibit the activity of HDAC 1,2,3 (class I) and 6 (class IIB), leading to a dose-dependent accumulation of acetylated histones and α-Tubulin, cell cycle arrest (G1/S phase) and apoptosis in breast cancer cells. Furthermore, the lead compound III could also antagonize the activation of STAT3 induced by HDACs inhibition in some breast cancer cells, which further reduced the level of pro-survive proteins in tumor cells and enhanced anti-tumor activity regulated by STAT3 signaling in vivo. Overall, findings demonstrated that the novel compound III might be a HDACs inhibitor candidate, which could be used as promising chemotherapeutic agent for breast cancer.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Synthetic Route of 4897-84-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Organobromine compounds have fallen under increased scrutiny for their environmental impact., SDS of cas: 2576-47-8.

Wei, Lina;Zhao, Jing;Meng, Yonghong;Guo, Yurong;Luo, Cangxue research published 《 Antibacterial activity, safety and preservative effect of aminoethyl-phloretin on the quality parameters of salmon fillets》, the research content is summarized as follows. Aminoethyl-phloretin (AEP), a novel water-soluble phloretin derivative, was synthesized from phloretin and 2-bromine ethylamine. Its antibacterial activity, safety, and preservative effect on salmon were studied. The structure of AEP was verified with UV, IR, ESI-MS and ¹H NMR, ¹³C NMR spectroscopy. HPLC anal. showed that the solubility of AEP was 430 times higher than that of phloretin. AEP exhibited a wide range of antibacterial activity on both Gram-pos. and Gram-neg. bacteria. The results of an acute oral-toxicity test in Kunming mice and a 30-days feeding subacute toxicity test on Sprague Dawley rats demonstrated that AEP was actually non-toxic. AEP also demonstated good preservative effects on salmon fish: the color, odor, taste and cooking method can maintain high-quality characteristics for 4 days; the level of fat oxidation and biogenic amines were reduced by 3.35 times and 10 times, resp.; the total bacterial and Pseudomonas spp. counts could be suppressed by 2 logarithms and 1.5 logarithms, resp., following treatment with 4 mg/mL of AEP. Thus, AEP significantly improved the solubility of phloretin, expanding its application scope and making it a promising preservative in the food industry.

2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., SDS of cas: 2576-47-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C6H6BBrO2.

Wei, Leping;Deng, Xin;Yu, Xiaohui;Li, Xiaohui;Wang, Wei;Zhang, Chunfang;Xiao, Jinchong research published 《 Double π-Extended Helicene Derivatives Containing Pentagonal Rings: Synthesis, Crystal Analyses, and Photophysics》, the research content is summarized as follows. Two novel double π-extended [n]helicene (n = 5, 6) derivatives (7b and 9) including pentagonal rings have been synthesized and characterized. Both of them have three isomers containing two enantiomers (P₆), (M₆), and a diastereoisomer in a meso form (P,M). X-ray single crystal analyses suggest that mols. 7b and 9 exhibit offset packing models of (P₆,P₅)- and (M₆,M₅)-isomers. Optical resolution of the resultant compound 7b was finished, and their chiroptical properties, as well as the DFT calculations, were also examined

COA of Formula: C6H6BBrO2, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Recommanded Product: (2-Bromophenyl)boronic acid.

Wei, Jingwen;Liu, Mengjia;Ye, Xiaohan;Zhang, Shuyao;Sun, Elaine;Shan, Chuan;Wojtas, Lukasz;Shi, Xiaodong research published 《 Facile synthesis of diverse hetero polyaromatic hydrocarbons (PAHs) via the styryl Diels-Alder reaction of conjugated diynes》, the research content is summarized as follows. The styryl dehydro-Diels-Alder reaction with a conjugated diyne was reported. While typical alkyne-styrene condensation requires elevated temperatures (>160°), the application of a conjugated diyne allowed for effective transformation under milder conditions (80°). The thermally stable triazole-gold (TA-Au) catalyst further improved the reaction yields (up to 95%), producing the desired alkynyl-naphthalene in a single step with mol. oxygen as the oxidant. Sequential alkyne activation resulted in various polyaromatic hydrocarbons (PAHs) in excellent yields, highlighting the efficiency of this new strategy for the preparation of PAHs with good functional group tolerance and structural diversity.

Recommanded Product: (2-Bromophenyl)boronic acid, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary