Month: November 2022

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application of C6H11BrO2.

Varmazyad, Mahboubeh;Modi, Mira M.;Kalen, Amanda L.;Sarsour, Ehab H.;Wagner, Brett;Du, Juan;Schultz, Michael K.;Buettner, Garry R.;Pigge, F. Christopher;Goswami, Prabhat C. research published 《 N-alkyl triphenylvinylpyridinium conjugated dihydroartemisinin perturbs mitochondrial functions resulting in enhanced cancer versus normal cell toxicity》, the research content is summarized as follows. Dihydroartemisinin (DHA) is an FDA-approved antimalarial drug that has been repurposed for cancer therapy because of its preferential antiproliferative effects on cancer vs. normal cells. Mitochondria represent an attractive target for cancer therapy based on their regulatory role in proliferation and cell death. This study investigates whether DHA conjugated to innately fluorescent N-alkyl triphenylvinylpyridinium (TPVP) perturbs mitochondrial functions resulting in a differential toxicity of cancer vs. normal cells. TPVP-DHA treatments resulted in a dose-dependent toxicity of human melanoma and pancreatic cancer cells, whereas normal human fibroblasts were resistant to this treatment. TPVP-DHA treatments resulted in a G₁-delay of the cancer cell cycle, which was also associated with a significant inhibition of the mTOR-metabolic and ERK1/2-proliferative signaling pathways. TPVP-DHA treatments perturbed mitochondrial functions, which correlated with increases in mitochondrial fission. In summary, TPVP mediated mitochondrial targeting of DHA enhanced cancer cell toxicity by perturbing mitochondrial functions and morphol.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Application of C6H11BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Formula: C6H7BrN2.

Varma, Reena R.;Pandya, Juhee G.;Vaidya, Foram U.;Pathak, Chandramani;Dabhi, Ravi A.;Dhaduk, Milan P.;Bhatt, Bhupesh S.;Patel, Mohan N. research published 《 DNA interaction, anticancer, antibacterial, ROS and lipid peroxidation studies of quinoxaline based organometallic Re(I) carbonyls》, the research content is summarized as follows. Hetero mononuclear rhenium(I) complexes (I-V) using ligands (L¹-L⁵) [L¹-L⁵ = 11-((2-chlorobenzylidene)hydrazono)-11H-indeno[1,2-b]quinoxaline (L¹), 8-methyl-11-((4-methyl-benzylidene)hydrazono)-11H-indeno[1,2-b]quinoxaline (L²), 11-((4-bromobenzylidene)hydrazono)-8-nitro-11H-indeno[1,2-b]quinoxaline (L³), 11-((4-bromobenzylidene) hydrazono)-8-chloro-11H-indeno[1,2-b]quinoxaline (L⁴), 8-bromo-11-((4-fluorobenzylidene) hydrazono)-11H-indeno[1,2-b]quinoxaline (L⁵)] were synthesized and characterized by spectroscopic method. All the synthesized compounds have biol. importance. DNA interaction studies gave information about the modes of binding and the nucleolytic efficiency of compounds The binding of the rhenium complexes to Herring sperm DNA (HS DNA) was monitored by UV-visible spectroscopy, viscosity measurements, and mol. docking studies; groove binding was suggested as the most possible mode. The DNA-complexes binding strength was measured in terms of intrinsic binding constants In vivo and In vitro cytotoxicity against the eukaryotic and prokaryotic cells gave the toxic nature of the synthesized compounds An antimicrobial study was carried out by estimating MIC (Min. Inhibitory Concentration) against two Gram-pos. (S. aureus, B. subtilis) and three Gram-neg. (S. marcescens, P. aeruginosa, E. coli) bacteria. All synthesized complexes are biol. more active than the corresponding ligands. Complexes were having higher MDA and H₂O₂ production than ligands.

Formula: C6H7BrN2, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 3-Bromobenzoic acid.

Vanjare, Balasaheb D.;Choi, Nam Gyu;Eom, Young Seok;Raza, Hussain;Hassan, Mubashir;Lee, Ki Hwan;Kim, Song Ja research published 《 Synthesis, carbonic anhydrase inhibition, anticancer activity, and molecular docking studies of 1,3,4-oxadiazole derivatives》, the research content is summarized as follows. In this work, various organic compounds possessing 1,3,4-oxadiazole as a core structure and the structure of the newly synthesized target compounds I (X = H, 2-Br, 3-Br, 4-Br; R = Ph, 4-fluorophenyl, pyridin-3-yl, etc.) has been revealed using different anal. approaches such as FT-IR, LCMS, and NMR (proton and carbon), resp. The in vitro carbonic anhydrase potentials of these synthesized 17 different analogs were investigated. The result suggests that compound I (X = H; R = pyridin-3-yl), a 3-pyridine substituted analog with an IC₅₀ of 0.1 μM, was found to have the most potent carbonic inhibitory activity (11-fold more active) than the pos. control (acetazolamide) with an IC₅₀ of 1.1 ± 0.1 μM. Besides, among the series I approved in the identification of four potent carbonic anhydrase inhibitors with the IC₅₀ standards varies from 0.1 to 1.0 ± 0.1 μM. Addnl., the non-competitive behavior for potent compound II was analyzed using the Lineweaver-Burk plot from the kinetic study. Furthermore, the anticancer activity of all the synthesized compounds screened against B16F10 melanoma cells using the MTT assay method. Addnl., the mol. docking studies revealed that II inhibitor shows good binding energy as well as good binding interaction pattern along with enzyme.

Recommanded Product: 3-Bromobenzoic acid, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organic compounds having carbon bonded to bromine are called organic bromides. Quality Control of 244205-40-1.

Van Phuc, Ban;Do, Ha Nam;Quan, Nguyen Minh;Tuan, Nguyen Ngoc;An, Nguyen Quang;Van Tuyen, Nguyen;Anh, Hoang Le Tuan;Hung, Tran Quang;Dang, Tuan Thanh;Langer, Peter research published 《 Copper-Catalyzed Synthesis of β- and δ-Carbolines by Double N-Arylation of Primary Amines》, the research content is summarized as follows. Two efficient and practical approaches are reported for the synthesis of β- and δ-carbolines from 3,4-dibromopyridine. The synthesis is based on site-selective Cu-catalyzed double C-N coupling reactions and subsequent annulations by twofold Pd-catalyzed C-N coupling with amines.

244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Quality Control of 244205-40-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 5445-17-0.

Vakarov, Sergey A.;Chulakov, Evgeny N.;Sadretdinova, Liliya Sh.;Kodess, Mikhail I.;Ezhikova, Marina A.;Pervova, Marina G.;Ganebnykh, Ilya N.;Levit, Galina L.;Krasnov, Victor P. research published 《 Kinetic Resolution of Racemic 2-Aryloxy Propionyl Chlorides Using Enantiopure (S)-3,4-Dihydro-3-methyl-2H-[1,4]benzoxazines》, the research content is summarized as follows. Stereoselectivity in the mutual kinetic resolution (KR) of racemic 2-aryloxy propionyl chlorides I [R = Ph, 1-naphthyl, MeS, etc.; Z = O, S, SO₂; Y = Cl] using chiral 3,4-dihydro-3-methyl-2H-[1,4]benzoxazines II [X = H, F] was studied. Based on the results obtained, preparative methods for single enantiomers of a series of 2-aryloxy propionic acids I [Y = OH; stereo = R or S] via acylative KR of their racemates with enantiopure (S)-3,4-dihydro-3-methyl-2H-[1,4]benzoxazines was proposed.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Electric Literature of 5445-17-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organic compounds having carbon bonded to bromine are called organic bromides. Application In Synthesis of 244205-40-1.

Umeda, Rui;Ueda, Ryo;Tanaka, Taiki;Hayashi, Akitsugu;Ikeshita, Masahiro;Suzuki, Shuichi;Naota, Takeshi;Nishiyama, Yutaka research published 《 Selective synthesis of 1-halonaphthalenes by copper-catalyzed benzannulation》, the research content is summarized as follows. The synthesis of 1-halonaphthalenes by the Cu-catalyzed benzannulation reaction of 2-(phenylethynyl)benzaldehyde and alkynes in the presence of the halogen reagents such as NBS, NCS, and NIS were developed. This protocol afforded various type of 1-halonaphthalenes in moderate to excellent yields and the cross coupling reactions of 1-bromo-2-phenylnaphthalene prepared by this method with various reagents occurred to give the corresponding 1,2-disubstituted naphthalenes.

Application In Synthesis of 244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. COA of Formula: C9H9BrO3.

Uenishi, Saho;Kakigi, Rina;Hideshima, Kumiko;Miyawaki, Akari;Matsuoka, Junpei;Ogata, Tokutaro;Tomioka, Kiyoshi;Yamamoto, Yasutomo research published 《 Asymmetric total synthesis of (-)-javaberine A and (-)-epi-javaberine A based on catalytic intramolecular hydroamination of N-methyl-2-(2-styrylaryl)ethylamine》, the research content is summarized as follows. Asym. total synthesis of (-)-javaberine A (I) and its epimer was achieved by utilizing two methods for isoquinoline synthesis, asym. hydroamination of N-methyl-2-(2-styrylaryl)ethylamine and Bischler-Napieralski cyclization. Intramol. asym. hydroamination of N-Me aminoalkene 4 was catalyzed by lithium amide-chiral bisoxazoline to give tetrahydroisoquinoline (S)-laudanosine with good enantioselectivity in excellent yield. N-Demethylation of (S)-laudanosine was accomplished by Polonovski-type reaction to give (S)-norlaudanosine. Condensation of (S)-norlaudanosine with homoveratric acid, and subsequent Bischler-Napieralski cyclization, LiAlH₄ reduction, and O-demethylation furnished (8R,14S)-(-)-javaberine A, corresponding to antipode of natural javaberine A. (8S,14S)-(-)-Javaberine A, which corresponds to C14-epimer of natural javaberine A, was also successfully synthesized.

COA of Formula: C9H9BrO3, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Name: 2-Bromoethylamine hydrobromide.

Uchida, Noriyuki;Yanagi, Masayoshi;Hamada, Hiroki research published 《 Piceid Nanoparticles Stabilized by Anionic Phospholipids for Transdermal Delivery》, the research content is summarized as follows. Piceid, stilbenoid glucoside, is a representative resveratrol derivative Because of a high tyrosinase inhibitory activity of piceid through resveratrol derivatives, transdermal delivery of piceid has been desired for taking advantage of the activity. Here we successfully prepared composite nanoparticles composed of anionic phospholipid of 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol (DPPG) and piceid by mixing them in water and a subsequent heating/cooling process. When small-sized fluorescently labeled DPPG-piceid (DPPG-^FLpiceid) nanoparticles were added to rat skin tissue, ^FLpiceid mols. were localized in stratum corneum.

Name: 2-Bromoethylamine hydrobromide, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Organic compounds having carbon bonded to bromine are called organic bromides. Product Details of C7H6Br2.

Turkmen, Yunus;Yagiz Erdemir, Gueler;Yuksel Mayda, Pelin;Akdemir, Atilla;Gunaydin Akyildiz, Aysenur;Altundas, Aliye research published 《 Synthesis, anti-TB activities, and molecular docking studies of 4-(1,2,3-triazoyl)arylmethanone derivatives》, the research content is summarized as follows. Infectious diseases such as tuberculosis (TB) are leading causes of human death. Antibiotics are effective mols. to combat bacterial infections by affecting the processes required for bacterial cell growth and proliferation. The development of new antibiotics has become an important issue as overdosed or incorrect use of antibiotic lead to the development of antibiotic resistance. In this study, a new series of 4-(1,2,3-triazoyl)arylmethanone derivatives has been synthesized using the one-pot Copper- Catalyzed Oxidative Cross- Dehydrogenative Coupling /Oxidative Cycloaddition strategy to overcome the aforementioned problems. New compounds were characterized by using spectroscopic techniques ¹H, ¹³C-APT-NMR, FT-IR, and HRMS-TOF. In vitro antimycobacterial activities of the arylmethanone derivatives against the Mycobacterium tuberculosis H37Rv standard strain were examined using the resazurin microplate method in the presence of streptomycin and rifampycin as standard medicines. Bioactive assays demonstrated promising results that some of the synthesized 4-(1,2,3-triazoyl)arylmethanone derivatives exhibited good anti-TB activities. Notably, compounds 6b, 6f, and 6g gave the most potent efficiency with min. inhibitory concentration values of 4 μg/mL (12.8, 11.7, and 12.8 μΜ, resp.). Among the synthesized compounds, the cytotoxicity measurements of the 6b, 6f, 6g, 6d, and 6v derivatives were screened and it was found that the 6f derivative did not show any cytotoxicity. Mol. docking analyses are utilized to identify the binding mode and the key interactions between target compounds and the ligand-binding site of M. tuberculosis enoyl-acyl carrier protein reductase enzyme (MtInhA, EC 1.3.1.9). The docking results were in agreement with the in vitro results, which confirm the synthesized ligands bind to MtInha with moderate to low affinity.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Product Details of C7H6Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 90-59-5, formula is C7H4Br2O2, The most pervasive is the naturally produced bromomethane. COA of Formula: C7H4Br2O2

Turan, Nouha Bakaraki;Zaman, Buse Tugba;Bakirdere, Emine Gulhan;Kartoglu, Bedrihan;Bakirdere, Sezgin research published 《 Simple and Green Vortex-Assisted Switchable Solvent Liquid Phase Microextraction for the Determination of Indium in Soil with Matrix Matching and Slotted Quartz Tube (SQT) – Flame Atomic Absorption Spectrometry (FAAS)》, the research content is summarized as follows. A novel preconcentration methodol. to enhance the sensitivity of a flame at. absorption spectrometer for indium determination was investigated in this study. The proposed methodol. is based on the application of switchable solvent based liquid-phase microextraction combined with a slotted quartz tube. The isolation of indium was performed using N, N-dimethylbenzylamine as the extraction solvent after complexation with (E)-2,4-dibromo-6-(((3-hydroxyphenyl)imino)methyl)phenol. The detection power was enhanced by approx. 169-fold using the developed method with respect to the conventional flame at. absorption spectrometry system. The quantification and detection limit values were 28.3 and 8.4 ng mL^-1, resp. The assessment of several interfering ions on the analyte was performed, and spike experiments were used to validate the method′s accuracy. Interferences were observed for a ratio of 1:10 analyte:interferent with a value of 27%. The recovery results obtained using matrix matching strategy indicated the applicability of the developed method for soil matrixes.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., COA of Formula: C7H4Br2O2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary