Hi, Jianxing published the artcileResearch on synthesis of chiral quinine quaternary ammonium ligand and its catalyzing activity for Darzens reaction, Name: 4-Bromo-1-(bromomethyl)-2-fluorobenzene, the publication is Guangdong Huagong (2013), 40(7), 27-29, 31, database is CAplus.
Through quaternization reaction of a series of halogenated hydrocarbons and quinine alkali, a series of chiral quinine quaternary ammonium salt ligands were generated with quinine as base matrix and its synthesized ligand structure was confirmed by 1H-NMR, IR and MS. And catalytic performance of ligands in Darzens condensation reaction between 2-chloroacetophenone and benzaldehyde in the asym. catalytic condition was investigated, implying that the chiral catalytic properties were associated with the steric size of substituents. And the best enantioselectivity of 46% was obtained.
Guangdong Huagong published new progress about 76283-09-5. 76283-09-5 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzyl bromide,Benzene, name is 4-Bromo-1-(bromomethyl)-2-fluorobenzene, and the molecular formula is C7H5Br2F, Name: 4-Bromo-1-(bromomethyl)-2-fluorobenzene.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary