Sap, Jeroen B. I.’s team published research in Chemical Science in 10 | CAS: 401-55-8

Chemical Science published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Application In Synthesis of 401-55-8.

Sap, Jeroen B. I. published the artcileSynthesis of 18F-difluoromethylarenes using arylboronic acids, ethyl bromofluoroacetate and [18F]fluoride, Application In Synthesis of 401-55-8, the publication is Chemical Science (2019), 10(11), 3237-3241, database is CAplus and MEDLINE.

Herein, the radiosynthesis of 18F-difluoromethylarenes RCHF18F (R = 4-C2H5, 4-OC6H5, 3,5-CH3, etc.) via the assembly of three components, a boron reagent, Et bromofluoroacetate, and cyclotron-produced non-carrier added [18F]fluoride was reported. The two key steps are a copper-catalyzed cross-coupling reaction, and a Mn-mediated 18F-fluorodecarboxylation.

Chemical Science published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Application In Synthesis of 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary