Wu, Yun published the artcileNickel-Catalyzed Monofluoroalkylation of Arylsilanes via Hiyama Cross-Coupling, Application In Synthesis of 401-55-8, the publication is Organic Letters (2016), 18(21), 5564-5567, database is CAplus and MEDLINE.
The first example of nickel-catalyzed monofluoroalkylation of arylsilanes has been developed with readily available fluoroalkyl halides. This novel transformation has demonstrated high reactivity, broad substrate scope, excellent functional group tolerance, and mild reaction conditions. The selective activation of a relatively inert C-Si bond for slow release of aryl carbanion is the key reason for reducing the amount of arylmetal species, which makes this method more promising for fluorine-containing modification of complex bioactive mols. Mechanistic investigations indicate that a free fluoroalkyl radical is involved in this catalytic cycle.
Organic Letters published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C6H12O2, Application In Synthesis of 401-55-8.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary