Seth, Punit P.’s team published research in Tetrahedron Letters in 43 | CAS: 53484-26-7

Tetrahedron Letters published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C12H10O4S, Synthetic Route of 53484-26-7.

Seth, Punit P. published the artcileEfficient solution phase synthesis of 2-(N-acylamino)benzimidazoles, Synthetic Route of 53484-26-7, the publication is Tetrahedron Letters (2002), 43(41), 7303-7306, database is CAplus.

An efficient solution phase protocol for the synthesis of 2-(N-acylamino)benzimidazoles is reported. The 2-(N-acylamino)benzimidazole ring system was assembled using SNAr reactions, nitro group reduction, acylthiourea formation and cyclization with EDC. The acyl protected 2-aminobenzimidazole derivatives were obtained in high yield and purity without purification of intermediates or final products. This reaction sequence eliminates the use of highly toxic cyanogen bromide, a reagent commonly used to prepare the 2-aminobenzimidazole ring system.

Tetrahedron Letters published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C12H10O4S, Synthetic Route of 53484-26-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary