1-benzyl-4-aza-1-azoniabicyclo[2.2.2]octane tribromide as a regenerable and useful reagent for bromination of phenols under mild conditions was written by Hajipour, Abdol R.;Pourmousavi, Seied A.;Ruoho, Arnold E.. And the article was included in Indian Journal of Chemistry in 2006.Quality Control of 4-Bromo-2-chloro-6-nitrophenol This article mentions the following:
1-Benzyl-4-aza-1-azoniabicyclo[2.2.2]octane tribromide was examined over several phenolic compounds under mild conditions. The reaction gives brominated phenols in good to excellent yields. Straightforward work-up of the reaction yields pure products in several cases. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-chloro-6-nitrophenol (cas: 58349-01-2Quality Control of 4-Bromo-2-chloro-6-nitrophenol).
4-Bromo-2-chloro-6-nitrophenol (cas: 58349-01-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Quality Control of 4-Bromo-2-chloro-6-nitrophenol
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary