Nitration of m-bromophenol was written by Hodgson, H. H.;Moore, F. H.. And the article was included in Journal of the Chemical Society in 1926.Formula: C6H4BrNO3 This article mentions the following:
Mononitration of m-BrC5H4OH with NaNO2 and H2SO4 gives a mixture of the 6-NO2 derivative, m. 42° (volatile with steam) (Me ether, m. 85.5°; benzoate, cream-colored, m. 104°; Na salt, scarlet needles) and the 4-NO2 derivative, yellowish white, m. 131° (Me ether, m. 45°; benzoate, cream-colored, m. 102°; Na salt, amber needles). HNO3 in oleum gives the 2-nitro derivative, bright yellow, m. 65-7°; Na salt, red needles; Me ether, m. 73°; benzoate, m. 133°; it forms a very labile, colorless hydrate, m. 35°; the yellow form reverts to the hydrate in moist air; the sensitiveness of the compound is such as to make it an approx. indicator of atm. humidity. The anhydrous yellow variety of 3-chloro-2-nitrophenol, m. 45-7°; the hydrate, with 1 H2O, m. 37.5-8°; this hydrate is much more stable in air than that of the Br derivative m-BrC6H4OH and 90.5% HNO3 in an equal volume of AcOH give the 4,6-(NO2)2 derivative, m. 92°; this also results from the 6- or 4-NO2 derivative and mixed acid (15 volumes 98% H2SO4, 12 volumes 70% HNO3 and 9 volumes H2O) and by boiling 1,3,4,6-Br2C6H2(NO2)2 with aqueous Na2CO3 6 hrs. Ag salt, yellow gelatinous precipitate gradually changing to a red crystalline form; in aqueous NH3 a yellow crystalline form results. The 2-NO2 derivative in the mixed acid gives the 2,6-dinitro derivative, m. 131°; a small amount is obtained from the 6-NO2 derivative in oleum (27% SO3) after 3 hrs. at 10° by nitrating with 90.5% HNO3 in oleum. Ag salt, red. The 2,4-dinitro derivative forms a yellow Ag salt. The 2,6- and 2.4-(NO2)2 derivatives may be separated by conversion into the Ag salts and digestion with NH4OH, the 2,6-(NO2)2 salt being soluble in cold NH4OH. Concentrated NH4OH converts both derivatives into 2,4,1,3-(O2N)2C6H2(NH2)3. NaOH gives 2,4,1,3-(O2N)2C6H2(OH)2. 3,2,4,6-Br(NO2)3C6HOH, m. 149°. 3-Bromo-2,5,6-trinitrophenol, m. 146°; the yellow Ag salt is soluble in H2O but insoluble in NH4OH. K 3-bromo-2,5,6-trinitrophenol-4-sulfonate, yellow, explodes on heating. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-nitrophenol (cas: 76361-99-4Formula: C6H4BrNO3).
3-Bromo-2-nitrophenol (cas: 76361-99-4) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Formula: C6H4BrNO3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary