Regueiro-Figueroa, Martin et al. published their research in Inorganic Chemistry in 2010 | CAS: 166821-88-1

2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane

Molecular Recognition of Sialic Acid by Lanthanide(III) Complexes through Cooperative Two-Site Binding was written by Regueiro-Figueroa, Martin;Djanashvili, Kristina;Esteban-Gomez, David;Chauvin, Thomas;Toth, Eva;de Blas, Andres;Rodriguez-Blas, Teresa;Platas-Iglesias, Carlos. And the article was included in Inorganic Chemistry in 2010.Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane This article mentions the following:

Herein the authors report two new ligands, 1,4,7-tris(carboxymethyl)-10-[2-(dihydroxyboranyl)benzyl]-1,4,7,10-tetraazacyclododecane (L1) and 1,4,7-tris(carboxymethyl)-10-[3-(dihydroxyboranyl)benzyl]-1,4,7,10-tetraazacyclododecane (L2), which contain a phenylboronic acid (PBA) function and a 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate cage for complexation of lanthanide ions in an aqueous solution The pKa of the PBA function amounts to 4.6 in [Gd(L1)] and 8.9 in [Gd(L2)], with the value of the L2 analog being very similar to that of PBA (8.8). These results are explained by the coordination of the PBA function of L1 to the GdIII ion, which results in a dramatic lowering of its pKa. As a consequence, [Gd(L1)] does not bind to saccharides at physiol. pH. The nuclear magnetic relaxation dispersion profiles recorded for [Gd(L1)] and [Gd(L2)] confirm that the phenylboronate function is coordinated to the metal ion in the L1 derivative, which results in a q = 0 complex. The interaction of the [Gd(L2)] complex with 5-acetylneuraminic acid (Neu5Ac) and 2-α-O-methyl-5-acetylneuraminic acid (MeNeu5Ac) was studied by spectrophotometric titrations in an aqueous solution (pH 7.4, 0.1M 3-(N-morpholino)propanesulfonic acid buffer). Also, the authors have also studied the binding of these receptors with competing monosaccharides such as D-(+)-glucose, D-fructose, D-mannose, D-galactose, Me α-D-galactoside, and Me α-D-mannoside. The binding constants obtained indicate an important selectivity of [Gd(L2)] for Neu5Ac (Keq = 151) over D-(+)-glucose (Keq = 12.3), D-mannose (Keq = 21.9), and D-galactose (Keq = 24.5). Also, a very weak binding affinity was observed in the case of Me α-D-galactoside and Me α-D-mannoside. An 8-fold increase of the binding constant of [Gd(L2)] with Neu5Ac is observed when compared to that of PBA determined under the same conditions (Keq = 19). 13C NMR spectroscopy and d. functional theory calculations performed at the B3LYP/6-31G(d) level show that this is due to a cooperative two-site binding of Neu5Ac through (1) ester formation by interaction on the PBA function of the receptor and (2) coordination of the carboxylate group of Neu5Ac to the GdIII ion. The emission lifetime of the 5D4 level of TbIII in [Tb(L2)] increases upon Neu5Ac binding, in line with the displacement of inner-sphere water mols. due to coordination of Neu5Ac to the metal ion. In the experiment, the researchers used many compounds, for example, 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane).

2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary