The action of ethyl chlorofumarate on monoalkylmalonic esters was written by Ruhemann, Siegfried. And the article was included in Journal of the Chemical Society, Transactions in 1902.Recommanded Product: 2178-24-7 This article mentions the following:
This study aims to prepare alkyl derivatives of aconitic acid, and to evaluate them on the same lines as aconitic acid itself. Although the actions of ethyl chlorofumarate on the sodium derivative of ethyl malonate does not yield ethyl carboxyaconitate but ethyl trimethylenetetracarboxylate, nevertheless such a transformation of the unsaturated grouping into the trimethylene compounds is excluded if, instead of ethyl malonate, its monoalkyl derivatives are used. The treatment of ethyl chlorofumarate with ethyl sodiomethylmalonate, 50% of ethyl methylcarboxyaconitate are produced, but the yields are as small as 6%, on using the phenyl or benzyl derivatives of malonic ester. In the experiment, the researchers used many compounds, for example, Ethyl (2-bromophenyl)acetate (cas: 2178-24-7Recommanded Product: 2178-24-7).
Ethyl (2-bromophenyl)acetate (cas: 2178-24-7) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Recommanded Product: 2178-24-7
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary