Synthesis of 7-aminoheptanoic acid hydrochloride was written by Xu, Juan-juan;Li, Jie-mei;Li, Xiao-zhu;Chen, Jia-shu. And the article was included in Xiandai Shipin Keji in 2010.Formula: C13H14BrNO2 This article mentions the following:
The synthesis of the target compound (i.e., 7-aminoheptanoic acid hydrochloride) was achieved by a sequence involving a reaction of dibromopentane with potassium phthalimide, formation of 2-(5-bromopentyl)-1H-isoindole-1,3(2H)-dione, reaction with propanedioic acid ester and formation of 2-[5-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)pentyl]propanedioic acid 1,3-di-Et ester and a subsequent hydrolysis and decarboxylation. The product was obtained in 55% overall yield and the structure was confirmed by 1H-NMR, LC-ELSD-UV-DAD-MS. In the experiment, the researchers used many compounds, for example, N-(5-Bromopentyl)phthalimide (cas: 954-81-4Formula: C13H14BrNO2).
N-(5-Bromopentyl)phthalimide (cas: 954-81-4) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Formula: C13H14BrNO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary