Monobromination of primary arylamines by NBS-DMF system was written by Yang, Hongqin;Cai, Junchao. And the article was included in Zhongguo Yaowu Huaxue Zazhi in 1995.SDS of cas: 615-55-4 This article mentions the following:
The reaction between equimolar N-bromosuccinimide (NBS) and some primary arylamines in dry DMF was systematically studied and it was found that NBS in DMF was ideal for the monobromination of primary arylamines. E.g., treating Et p-aminobenzoate with NBS in DMF at room temp gave 92% Et 2-bromo-4-aminobenzoate. In the experiment, the researchers used many compounds, for example, 3,4-Dibromoaniline (cas: 615-55-4SDS of cas: 615-55-4).
3,4-Dibromoaniline (cas: 615-55-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. SDS of cas: 615-55-4
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary