Month: December 2022

Cary, Douglas R. published the artcileRhenium bipyridine complexes for the recognition of glucose, Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane, the publication is Inorganic Chemistry (2002), 41(6), 1662-1669, database is CAplus and MEDLINE.

Bipyridine ligands containing pendant Me, amino, and amino-boronic acid groups were synthesized. Coordination complexes of these ligands with rhenium were prepared straightforwardly and in good yield. The fluorescence behavior of the Re complexes was studied as a function of pH and exposure to various concentrations of glucose. The Me bipyridine complex showed no change in fluorescence with pH, the amino derivative showed a rapid decrease from low pH to neutral, and the amino-boronate derivative showed little change from pH 4 to 10. Fluorescence quenching was observed at high pH as expected on the basis of a photoinduced electron transfer (PET) signaling mechanism. This behavior can be explained on the basis of the first oxidation and reduction potentials of these complexes. Glucose testing showed a significant dependence on the solvent system used. In pure methanol, the rhenium boronate complex exhibited a 55% fluorescence intensity increase upon increasing glucose concentration from 0 to 400 mg/dL. However, in 50 vol % methanol/phosphate buffered saline, none of the complexes showed significant response in the glucose range of physiol. interest.

Inorganic Chemistry published new progress about 166821-88-1. 166821-88-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzyl bromide,Benzene,Boronic Acids,Boronic acid and ester, name is 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane, and the molecular formula is C12H16BBrO2, Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Taniguchi, Tsuyoshi published the artcileFormal Total Synthesis of Haouamine A, Synthetic Route of 89694-44-0, the publication is Journal of Organic Chemistry (2009), 74(6), 2624-2626, database is CAplus and MEDLINE.

A synthesis of the indenotetrahydropyridine unit I of haouamine A is described. The construction of a diaryl quaternary center and tricyclic framework of this compound was achieved by an intramol. cascade Mizoroki-Heck reaction.

Journal of Organic Chemistry published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C15H21BO2, Synthetic Route of 89694-44-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Correy, Galen J. published the artcileOvercoming insecticide resistance through computational inhibitor design, Application of (3-Bromo-5-isopropoxyphenyl)boronic acid, the publication is Proceedings of the National Academy of Sciences of the United States of America (2019), 116(42), 21012-21021, database is CAplus and MEDLINE.

Insecticides allow control of agricultural pests and disease vectors and are vital for global food security and health. The evolution of resistance to insecticides, such as organophosphates (OPs), is a serious and growing concern. OP resistance often involves sequestration or hydrolysis of OPs by carboxylesterases. Inhibiting carboxylesterases could, therefore, restore the effectiveness of OPs for which resistance has evolved. Here, we use covalent virtual screening to produce nano-/picomolar boronic acid inhibitors of the carboxylesterase αE7 from the agricultural pest Lucilia cuprina as well as a common Gly137Asp αE7 mutant that confers OP resistance. These inhibitors, with high selectivity against human acetylcholinesterase and low to no toxicity in human cells and in mice, act synergistically with the OPs diazinon and malathion to reduce the amount of OP required to kill L. cuprina by up to 16-fold and abolish resistance. The compounds exhibit broad utility in significantly potentiating another OP, chlorpyrifos, against the common pest, the peach-potato aphid (Myzus persicae). These compounds represent a solution to OP resistance as well as to environmental concerns regarding overuse of OPs, allowing significant reduction of use without compromising efficacy.

Proceedings of the National Academy of Sciences of the United States of America published new progress about 871125-81-4. 871125-81-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Bromo-5-isopropoxyphenyl)boronic acid, and the molecular formula is C9H12BBrO3, Application of (3-Bromo-5-isopropoxyphenyl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xu, Zhen published the artcileColor tuning for black-to-transmissive conjugated copolymer with excellent electrochromic properties via electrochemical copolymerization of two donor-acceptor type monomers, Related Products of bromides-buliding-blocks, the publication is Materials & Design (2020), 108903, database is CAplus.

Copolymerization towards producing broadly absorbing black neutrality for flexible electrochromics was investigated. Neutral-state saturated green and dark blue donor-acceptor-donor (D-A-D) polymers consisting of electron-acceptor thieno[3,4-b]pyrazine and benzo[1,2,3]triazole based units resp., were chosen as distributed segments, simultaneous with their tendency to switch to transmissive oxidation states. Variation of the feed ratio of two precursors in a mixture solution was used to regulate the energy and spectral absorption range of electrochem. copolymerization films. Co-polymer PEM-11 in 1:1 monomer feed ratio demonstrated a full range of visible absorption, and switched between an improved saturated black neutral state (L* = 43.68, a* = 4.98, b* = -13.13) and a light gray transmissive oxidation state (L* = 67.30, a* = -1.36, b* = 1.67) reversibly, where L* represents white to black balance, a* red to green and b* yellow to blue, with the optical contrast of 35% at 590 nm and switching speed as low as 0.6 s. Furthermore, the PEM-11 film exhibited stable n-doping, favorable cycle stability, and a lower electrochem./optical band-gap (0.80 eV/1.21 eV) in comparison with the reported individual neutral black ECPs. The results suggested that the as-obtained copolymer could be a promising candidate for electrochromic windows, e-papers, or eyewear applications.

Materials & Design published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C13H10F2, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhu, Jing published the artcileSynthesis of 2,3-Dialkylated Tartaric Acid Esters via Visible Light Photoredox-Catalyzed Reductive Dimerization of α-Ketoesters, Computed Properties of 69361-41-7, the publication is ACS Omega (2017), 2(8), 4665-4677, database is CAplus and MEDLINE.

A mild transition-metal-free protocol to prepare 2,3-dialkylated tartaric acid esters has been developed by taking advantage of a visible light photoredox-catalyzed reductive dimerization of α-ketoesters with a combination of an organic dye photocatalyst and a Hantzsch-type 1,4-dihydropyridine hydrogen donor. A broad range of functional groups including cyclopropane, alkene, alkyne, 4-methoxybenzyl ether, acetal, silyl ether, carbamate, cyclic ether, cyclic thioether, bromoalkane, and N-alkoxyphthalimide are well-compatible. By employing the visible light photoredox-catalyzed reductive coupling and the subsequent optical resolution, both enantioenriched diastereomers of 2,3-dialkylated tartaric acid could be acquired conveniently.

ACS Omega published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C24H29N5O3, Computed Properties of 69361-41-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhang, Bo published the artcile3,4-Dicyanothiophene-a Versatile Building Block for Efficient Nonfullerene Polymer Solar Cells, Quality Control of 52431-30-8, the publication is Advanced Energy Materials (2020), 10(12), 1904247, database is CAplus.

In this contribution, a versatile building block, 3,4-dicyanothiophene (DCT), which possesses structural simplicity and synthetic accessibility for constructing high-performance, low-cost, wide-bandgap conjugated polymers for use as donors in polymer solar cells (PSCs), is reported. A prototype polymer, PB3TCN-C66, and its cyano-free analog polymer PB3T-C66, are synthesized to evaluate the potential of using DCT in nonfullerene PSCs. A stronger aggregation property in solution, higher thermal transition temperatures with higher enthalpies, a larger dipole moment, higher relative dielec. constant, and more linear conformation are exhibited by PB3TCN-C66. Solar cells employing IT-4F as the electron acceptor offer power conversion efficiencies (PCEs) of 11.2% and 2.3% for PB3TCN-C66 and PB3T-C66, resp. Morphol. characterizations reveal that the PB3TCN-C66:IT-4F blend exhibits better π-π paracrystallinity, a contracted domain size, and higher phase purity, consistent with its higher mol. interaction parameter, derived from thermodn. calculations Moreover, PB3TCN-C66 offers a higher open-circuit voltage and reduced energy loss than most state-of-the-art wide-bandgap polymers, without the need of addnl. electron-withdrawing substituents. Two addnl. polymers derived from DCT also demonstrate promising performance with a higher PCE of 13.4% being achieved. Thus, DCT represents a versatile and promising building block for constructing high-performance, low-cost, conjugated polymers for application in PSCs.

Advanced Energy Materials published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C12H16N2O2, Quality Control of 52431-30-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xu, Wei Ming published the artcilePolystyrene-supported benzyl selenide: An efficient reagent for highly stereo-controlled synthesis of substituted olefins, Application of Diethyl (bromomethyl)phosphonate, the publication is Chinese Chemical Letters (2003), 14(4), 335-337, database is CAplus.

Polystyrene-supported benzyl selenide has been prepared This novel reagent was treated with LDA to produce a selenium stabilized carbanion, which reacted with alkyl halide, followed by selenoxide syn-elimination, to give substituted olefins stereospecifically.

Chinese Chemical Letters published new progress about 66197-72-6. 66197-72-6 belongs to bromides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyl (bromomethyl)phosphonate, and the molecular formula is C14H21BO3, Application of Diethyl (bromomethyl)phosphonate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kim, Ki-Hyun published the artcileInfluence of intermolecular interactions of electron donating small molecules on their molecular packing and performance in organic electronic devices, Synthetic Route of 303734-52-3, the publication is Journal of Materials Chemistry A: Materials for Energy and Sustainability (2013), 1(46), 14538-14547, database is CAplus.

Intermol. interactions have a critical role in determining the mol. packing and orientation of conjugated polymers and organic mols., leading to significant changes in their elec. and optical properties. Herein, the authors studied the effects of intermol. interactions of electron-donating small mols. on their structural, optical, and elec. properties, as well as on their performance in organic field-effect transistors (OFETs) and organic photovoltaics (OPVs). Dithienosilole-based small mol. donors were synthesized by introducing different terminal groups of ester and amide groups combined with 3 different versions of alkyl side chains. In comparison to dithienosilole-based small mols. with ester terminal groups, those with amide terminal groups exhibit strong intermol. interaction by H bonding in a nondestructive manner. To control the intermol. distance during assembly and thus fine-tune the interaction between the small mol. donors, 3 different alkyl side chains (i.e., n-octyl, n-decyl, and 2-ethylhexyl chains) were introduced into both small mols. with amide and ester terminal groups. The mol. packing and orientation of the small mol. donors were dramatically changed upon modifying the terminal groups and the alkyl side chains, as evidenced by grazing incidence x-ray scattering (GIXS) measurements. This feature significantly affected the elec. properties of the small mols. in OFETs. The trends in the activation energies for charge transport and the hole mobilities in OFETs were consistent with the mol. ordering and orientation propensity. The nano-scale morphol. of small mols. blended with [6,6]-phenyl-C₆₁-butyric acid Me ester (PCBM) was also influenced by the intermol. interaction of small mol. donors. Power conversion efficiencies of >4.3% in OPVs were obtained from dithienosilole-based small mols. with ester terminal groups and linear side chains due to the optimized intermol. interaction and morphol. of the active layer.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C12H19BrS, Synthetic Route of 303734-52-3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Coutrot, P. published the artcileDiethyl (chloromagnesio)methanephosphonate. A novel Grignard reagent and its use in organic synthesis, HPLC of Formula: 66197-72-6, the publication is Journal of Organometallic Chemistry (1986), 316(1-2), 13-18, database is CAplus.

(EtO)₂P(O)CH₂MgCl (I) was obtained by an exchange reaction between (EtO)₂P(O)CH₂I and Me₂CHMgCl in THF at -70°. Reactions of I with electrophiles are described, and compared with those of the analogous lithium or copper derivatives E.g. I reacted with PhCHO to give (EtO)₂P(O)CH₂CH(OH)Ph. I is especially reactive towards phenylselenium halides and halogens.

Journal of Organometallic Chemistry published new progress about 66197-72-6. 66197-72-6 belongs to bromides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyl (bromomethyl)phosphonate, and the molecular formula is C5H12BrO3P, HPLC of Formula: 66197-72-6.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chen, Fener published the artcileSynthesis of ibuprofen by rearrangement, Recommanded Product: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Zhongguo Yiyao Gongye Zazhi (1992), 23(1), 1-2, database is CAplus.

On the basis of the Giordano’s method, ibuprofen was synthesized with some improvements in 75% overall yield from isobutylbenzene. The mild reaction conditions, convenient work-up and higher purity of the product were advantages of this method.

Zhongguo Yiyao Gongye Zazhi published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Recommanded Product: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary