Month: December 2022

Park, P. J. D. published the artcileSpectroscopic and acoustic studies on the rotational isomerism in 2,3-dibromo-2,3-dimethylbutane, Name: 2,3-Dibromo-2,3-dimethylbutane, the publication is Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical (1968), 2064-7, database is CAplus.

The vibrational spectra of 2,3-dibromo-2,3-dimethylbutane (I) were measured in various phases. In the liquid phase, I exists as an equilibrium mixture of rotational isomers. A proposed frequency assignment of the gaucheand trans-isomers is given. A value of 6-7.5 kcal./mole was estimated for the energy of activation for the gauche → trans isomerization from acoustic measurements at ∼50°.

Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Name: 2,3-Dibromo-2,3-dimethylbutane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Park, P. J. D. published the artcileThe infrared spectra of pressed-disk samples in relation to molecular structure in 2,3-dibromo-2,3-dimethylbutane, Computed Properties of 594-81-0, the publication is Chemical Communications (London) (1966), 557-8, database is CAplus.

The ir spectra of 2,3-dibromo-2,3-dimethylbutane (I) were determined for mull, crystal, dilute solution, liquid at high temperatures, and mull pressed-disk samples in order to clarify discrepancies between earlier spectroscopic and dipole-moment studies. The spectra of solid mull and crystal samples were in agreement with those reported previously. When the ir and Raman spectra of the crystal form were compared, the rule of mutual exclusion was found to apply. The crystal was entirely the trans form with mol. sym. C_2h. When the ir spectra of liquid I and dilute solutions were examined, addnl. weak absorption bands unreported previously were observed at 1283, 1263, 1190, 1055, 1020, 1005, 947, 925, 682, and 490 cm.^-1 These were assigned to the gauche isomer. Addnl. bands appeared also in the pressed-disk spectrum of I, corresponding almost exactly in frequency to those bands assigned to the gauche compound During the preparation of the pressed-disk samples, internal rotation was concluded to have occurred, with some mols. changing from the trans to the gauche form.

Chemical Communications (London) published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Computed Properties of 594-81-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ren, Rongguo published the artcileSynergistic Strategies of Cyano Migration and Photocatalysis for Difunctionalization of Unactivated Alkenes: Synthesis of Di- and Mono-Fluorinated Alkyl Nitriles, Product Details of C4H6BrFO2, the publication is Advanced Synthesis & Catalysis (2017), 359(17), 3052-3056, database is CAplus.

A general protocol for the challenging cyanofluoroalkylation of unactivated alkenes is disclosed. A broad range of synthetically useful di- and mono-fluorinated alkyl nitriles are readily obtained in good yields under mild reaction conditions [e.g, cyanohydrin I + BrCF₂CO₂Et → nitrile II (90%) under blue LED irradiation in presence of fac-Ir(ppy)₃ in DMF]. The efficient combination of intramol. cyano migration and photoredox catalysis significantly expands the field of difunctionalization of olefins.

Advanced Synthesis & Catalysis published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Product Details of C4H6BrFO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Zhitao published the artcileAnalysis of coal tar pitch and smoke extract components and their cytotoxicity on human bronchial epithelial cells, Formula: C4Br2N2O4S, the publication is Journal of Hazardous Materials (2011), 186(2-3), 1277-1282, database is CAplus and MEDLINE.

Coal tar pitch and its smoke are considered hazardous byproducts and common pollutants generated by the coal processing industry. This work characterized coal tar pitch and its smoke extracts by gas chromatog./mass spectrometry (GC/MS) using dimethylsulfoxide. Only 0.3025% of components in total coal tar pitch were identified by GC/MS. Among 18 identified compounds, polycyclic aromatic hydrocarbons (PAH) has the highest relative abundance (0.19%). Remaining components were composed of monocyclic aromatic hydrocarbons, heterocyclic compounds, and alkenes. Among 38 coal tar pitch smoke extract constituents profiled, 87.91% were PAH; the remaining 12.09% were composed of monocyclic aromatic hydrocarbons, heterocyclic compounds, and alkenes. The cytotoxic effect of coal tar pitch and its smoke extracts on BEAS-2B cells were also evaluated using the MTT assay. BEAS-2B cells exposed to coal tar pitch exhibited a non dose-dependent, U-shaped cytotoxicity with the maximum ID of 3.75 mg/L. BEAS-2B cells exposed to coal tar pitch smoke extracts exhibited dose-dependent cytotoxicity with a 8.64 mg/L LC₅₀. Results demonstrated the significant different composition and cytotoxicity of coal tar pitch and its extracts, suggesting 2 underlying mechanisms which are pending future investigation.

Journal of Hazardous Materials published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Formula: C4Br2N2O4S.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Wu, Shuo published the artcileRegioselective Vinylation of Remote Unactivated C(sp³)-H Bonds: Access to Complex Fluoroalkylated Alkenes, Product Details of C4H6BrFO2, the publication is Angewandte Chemie, International Edition (2019), 58(5), 1499-1503, database is CAplus and MEDLINE.

Regioselective incorporation of a particular functional group into aliphatic sites by direct activation of unreactive C-H bonds is of great synthetic value. Despite advances in radical-mediated functionalization of C(sp³)-H bonds by a hydrogen-atom transfer process, the site-selective vinylation of remote C(sp³)-H bonds still remains underexplored. Reported herein is a new protocol for the regioselective vinylation of unactivated C(sp³)-H bonds. The remote C(sp³)-H activation is promoted by a C-centered radical instead of the commonly used N and O radicals. The reaction possesses high product diversity and synthetic efficiency, furnishing a plethora of synthetically valuable E alkenes bearing tri-/di-/mono-fluoromethyl and perfluoroalkyl groups.

Angewandte Chemie, International Edition published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C8H16O2, Product Details of C4H6BrFO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tang, Nana published the artcilePractical, metal-free remote heteroarylation of amides via unactivated C(sp³)-H bond functionalization, Application of (2-Bromoethyl)cyclopentane, the publication is Chemical Science (2019), 10(28), 6915-6919, database is CAplus and MEDLINE.

A new, efficient, site-selective heteroarylation of amides via C(sp³)-H bond functionalization. Amidyl radicals were directly generated from the amide N-H bonds under mild conditions, which triggered the subsequent 1,5-HAT process. A wide scope of aliphatic amides including carboxamides, sulfonamides and phosphoramides were readily modified at remote C(sp³)-H bonds by installing diverse heteroaryl groups. Borne out of pragmatic consideration, this protocol was used for the late-stage functionalization of amides.

Chemical Science published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C3H9ClOS, Application of (2-Bromoethyl)cyclopentane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Han, Shuaijun published the artcileCopper-catalyzed remote C-H monofluoromethylation of 8-aminoquinolines with dimethyl phosphonate as reductant, Related Products of bromides-buliding-blocks, the publication is Tetrahedron Letters (2019), 60(40), 151077, database is CAplus.

A simple and efficient copper-catalyzed monofluoromethylation of 8-aminoquinolines with 2-bromo-2-fluoroacetate was described with HPO(OMe)₂ (di-Me phosphonate) as reductant. The reaction tolerated a variety of quinoline amides and monofluoroalkyl bromides. Significant advantages of this protocol include synthetic convenience and high reaction efficiency.

Tetrahedron Letters published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Huang, Pengmian published the artcileDesign, synthesis and insecticidal activities of new meta-diamide compounds containing n-butyl group, Application of 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, the publication is Tetrahedron Letters (2022), 153743, database is CAplus.

In order to discover a novel insecticide, a series of meta-diamide compounds containing Bu group were designed and synthesized. Preliminary bioassay data showed that some of the target compounds exhibited good insecticidal activities against Plutella xylostella, Spodoptera frugiperda and Alfalfa sprouts. In particular, compounds 6d and 6n displayed 100% insecticidal activity against Plutella xylostella at 1 mg/L and also revealed 100% of mortality rate against Spodoptera frugiperda at 0.1 mg/L, which was consistent with the cyproflanilide. Meanwhile, compound 6m showed 98.89% insecticidal activity against Alfalfa sprouts at 100 mg/L, better than cyproflanilide (25.60% at 100 mg/L). The work demonstrated that compounds containing Bu group might supply certain hints toward structure optimization design for the development of new insecticides.

Tetrahedron Letters published new progress about 1207314-86-0. 1207314-86-0 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Amine,Benzene, name is 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline, and the molecular formula is C10H4BrF10N, Application of 2-Bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Jin, Weiwei published the artcileVisible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenes, Application In Synthesis of 401-55-8, the publication is Chemical Communications (Cambridge, United Kingdom) (2018), 54(57), 7924-7927, database is CAplus and MEDLINE.

A visible-light induced three-component reaction of difluoroalkyl halides, unactivated alkenes, and alkynyl sulfones is described, providing a direct and general approach to the construction of synthetically valuable β-difluoroalkylated alkynes under room temperature conditions. This represents the first intermol. alkynyl-difluoroalkylation of unactivated alkenes.

Chemical Communications (Cambridge, United Kingdom) published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Application In Synthesis of 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xie, Ke published the artcilePoly(3,4-dinitrothiophene)/SWCNT composite as a low overpotential hydrogen evolution metal-free catalyst, Quality Control of 52431-30-8, the publication is Journal of Materials Chemistry A: Materials for Energy and Sustainability (2015), 3(1), 78-82, database is CAplus.

A novel metal-free H evolution reaction catalyst made of poly(3,4-dinitrothiophene)/SWCNT was developed. This catalyst presents a good H evolution reaction activity with a lower overpotential than metallic catalysts. Its performance was optimized to an overpotential of ∼0.040 V and a H generation rate of 44.2 μmol h^-1 cm^-2.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C9H9NO, Quality Control of 52431-30-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary