Month: December 2022

Tian, Yong published the artcileNovel metal complexes of pyridineimine derivative used as auxiliary electron acceptor of D-(A-π-A)₂ motif dye sensitizer: synthesis and photovoltaic application, SDS of cas: 111-83-1, the publication is Journal of Solid State Electrochemistry (2022), 26(3), 719-727, database is CAplus.

The auxiliary acceptors of metal complexes can easily regulate the electron-withdrawing ability of electron acceptor and adjust the balance of push-pull electron of D-A-π-A motif dye sensitizers. Two series of the D-(A-π-A)₂ motif dye sensitizer (BDTT-i.m.-Co, BDTT-i.m.-Cu, BDTT-i.m.-Zn, BDTT-i.m.-Cd and FL-i.m.-Co, FL-i.m.-Cu, FL-i.m.-Zn, FL-i.m.-Cd) which use metal complexes of pyridineimine derivative as auxiliary acceptor were designed, synthesized, and characterized. The photovoltaic test of eight complex-based dye sensitized solar cells (DSSCs) showed that the short-circuit photocurrent d. (J_SC) and the power conversion efficiency (PCE) of two series dye sensitizers are sequentially increased. BDTT-i.m.-Cd have the highest J_SC of 15.58 mA cm^-2 and the PCE of 9.13% under AM 1.5 irradiation, which may be due to that electron-withdrawing ability of the auxiliary acceptor metal complexes of pyridineimine derivative can be changed by the strength of coordination bond of the complexes. They also show good terminal stability with decomposition temperatures (T_d) higher than 300 °C.

Journal of Solid State Electrochemistry published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C9H7NO2, SDS of cas: 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zheng, Qi-Huang published the artcileAn Improved Total Synthesis of PET HSV-tk Gene Reporter Probe 9-(4-[18F]Fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG), Formula: C8H15BrO2, the publication is Synthetic Communications (2004), 34(4), 689-704, database is CAplus.

An improved total synthesis of [18F]FHBG (I) starting from triethyl-1,1,2-ethanetricarboxylate and 2-amino-6-chloropurine is reported. [18F]FHBG was prepared by nucleophilic substitution of the appropriate precursor with [18F]KF/Kryptofix 2.2.2 followed by a quick deprotection reaction and purification with a simplified Silica Sep-Pak solid-phase extraction (SPE) method in 20-25% radiochem. yield.

Synthetic Communications published new progress about 97845-58-4. 97845-58-4 belongs to bromides-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Bromide, name is 5-(2-Bromoethyl)-2,2-dimethyl-1,3-dioxane, and the molecular formula is C9H4F6O, Formula: C8H15BrO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chen, Yasu published the artcileRadical-Mediated Functionalization of Internal Alkenes: Synthesis of Multisubstituted Allylic and Homoallylic Azides, COA of Formula: C4H6BrFO2, the publication is ACS Organic & Inorganic Au, database is CAplus.

Radical-mediated functionalization of alkenes provides a powerful tool for transformation of simple alkenes into numerous value-added products. The precedent radical functionalization of alkenes is mainly restricted to terminal alkenes, while the conversion of internal alkenes generally remains challenging, as the increased steric congestion on alkenes significantly conflicts with the intermol. addition of radicals. Herein, authors describe an efficient photoredox catalytic functionalization of internal trisubstituted alkenes, leading to a plethora of valuable multifunctionalized allylic and homoallylic azides, which are otherwise difficult to obtain. The azide products serve as versatile feedstock for construction of useful heterocycles. Allylic or homoallylic azides are selectively generated in the transformation, regulated by the regioselective deprotonation process. This method also features mild reaction conditions and high product diversity.

ACS Organic & Inorganic Au published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, COA of Formula: C4H6BrFO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chen, Junfeng published the artcileEnzyme-like Click Catalysis by a Copper-Containing Single-Chain Nanoparticle, HPLC of Formula: 81216-14-0, the publication is Journal of the American Chemical Society (2018), 140(42), 13695-13702, database is CAplus and MEDLINE.

A major challenge in performing reactions in biol. systems is the requirement for low substrate concentrations, often in the micromolar range. We report that copper cross-linked single-chain nanoparticles (SCNPs) are able to significantly increase the efficiency of copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reactions at low substrate concentration in aqueous buffer by promoting substrate binding. Using a fluorogenic click reaction and dye uptake experiments, a structure-activity study is performed with SCNPs of different size and copper content and substrates of varying charge and hydrophobicity. The high catalytic efficiency and selectivity are attributed to a mechanism that involves an enzyme-like substrate binding process. Saturation-transfer difference (STD) NMR spectroscopy, 2D-NOESY NMR, kinetic analyses with varying substrate concentrations, and computational simulations are consistent with a Michaelis-Menten, two-substrate, random-sequential enzyme-like kinetic profile. This general approach may prove useful for developing more-sustainable catalysts and agents for biomedicine and chem. biol.

Journal of the American Chemical Society published new progress about 81216-14-0. 81216-14-0 belongs to bromides-buliding-blocks, auxiliary class Linker,PROTAC Linker, name is 7-Bromohept-1-yne, and the molecular formula is C7H11Br, HPLC of Formula: 81216-14-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Yu, Jiajia published the artcileDistal Functional Group Migration for Visible-light Induced Carbo-difluoroalkylation/monofluoroalkylation of Unactivated Alkenes, COA of Formula: C4H6BrFO2, the publication is Advanced Synthesis & Catalysis (2018), 360(4), 744-750, database is CAplus.

A general and practical protocol for elusive carbo-difluoroalkylation/monofluoroalkylation of unactivated alkenes HOCR¹R²(CH₂)₂CH:CH₂ (R¹ = n-pentyl, 2-thienyl, Ph, etc.; R² = CHO, 2-benzothiazolyl, PhCC, etc.) with fluoroalkyl bromides R³R⁴CFBr (R³ = EtO₂C, R⁴ = H, F; R³ = Br, PhSO₂, morpholin-4-ylcarbonyl, R⁴ = F) based on the distal functional group migration is described. A portfolio of functional groups including heteroaryl, imino, formyl, and alkynyl groups showcase the migratory aptitude. In combination with visible-light photocatalysis, a broad range of di- and mono-fluorinated alkyl ketones R¹C(O)(CH₂)₂CHR²CH₂CFR³R⁴ were readily obtained in synthetically useful yields under mild reaction conditions.

Advanced Synthesis & Catalysis published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C11H14O4, COA of Formula: C4H6BrFO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lv, Xu-Lu published the artcileRapid Synthesis of γ-Arylated Carbonyls Enabled by the Merge of Copper- and Photocatalytic Radical Relay Alkylarylation of Alkenes, SDS of cas: 401-55-8, the publication is Organic Letters (2019), 21(1), 56-59, database is CAplus and MEDLINE.

The development of mild and practical methods for the γ-arylation of carbonyl compounds is an ongoing challenge in organic synthesis. The first formal γ-arylation of carbonyl compounds via radical relay cross-coupling of α-bromocarbonyl precursors with boronic acids in the presence of alkenes is reported. This directing-group-free protocol allows for the rapid and straightforward access to a wide range of γ-arylated esters, ketones, and amides under ambient conditions with excellent functional group tolerance.

Organic Letters published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, SDS of cas: 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xu, Xiaofeng published the artcilePyrrolo[3,4-g]quinoxaline-6,8-dione-based conjugated copolymers for bulk heterojunction solar cells with high photovoltages, Formula: C4Br2N2O4S, the publication is Polymer Chemistry (2015), 6(25), 4624-4633, database is CAplus.

A new electron-deficient building block 5,9-di(thiophen-2-yl)-6H-pyrrolo[3,4-g]quinoxaline-6,8(7H)-dione (PQD) was synthesized via functionalizing the 6- and 7-positions of quinoxaline (Qx) with a dicarboxylic imide moiety. Side chain substitution on the PQD unit leads to good solubility which enables very high mol. weight copolymers to be attained. The fusion of two strong electron-withdrawing groups (Qx and dicarboxylic imide) makes the PQD unit a stronger electron-deficient moiety than if the unit had just one electron-withdrawing group, thus enhancing the intramol. charge transfer between electron-rich and deficient units of the copolymer. Four PQD-based polymers were synthesized which feature deep-lying HOMO (HOMO) levels and bathochromic absorption spectra when compared to PBDT-Qx and PBDT-TPD analogs. The copolymers incorporated with benzo[1,2-b:4,5-b’]dithiophene (BDT) units show that the 1D and 2D structural variations of the side groups on the BDT unit are correlated with the device performance. As a result, the corresponding solar cells (ITO/PEDOT:PSS/polymer:PC₇₁BM/LiF/Al) based on the four copolymers feature very high open-circuit voltages (V_oc) of around 1.0 V. The copolymer PBDT-PQD1 attains the best power conversion efficiency of 4.9%, owing to its relatively high absorption intensity and suitable film morphol. The structure-property correlation demonstrates that the new PQD unit is a promising electron-deficient building block for efficient photovoltaic materials with high V_oc.

Polymer Chemistry published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C19H21N3O3S, Formula: C4Br2N2O4S.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhang, Wei published the artcileCopper-Catalyzed Decarboxylative Functionalization of Conjugated β,γ-Unsaturated Carboxylic Acids, Application In Synthesis of 401-55-8, the publication is ACS Catalysis (2020), 10(22), 13179-13185, database is CAplus and MEDLINE.

Copper-catalyzed decarboxylative coupling reactions of conjugated β,γ-unsaturated carboxylic acids have been achieved for allylic amination, alkylation, sulfonylation, and phosphinoylation. This approach was effective for a broad scope of amino, alkyl, sulfonyl, and phosphinoyl radical precursors as well as various conjugated β,γ-unsaturated carboxylic acids. These reactions also feature high regioselectivity, good functional group tolerance, and simple operation procedure. Mechanistic studies show that the reaction proceeds via copper-catalyzed electrophilic addition onto an olefin followed by decarboxylation, with radical intermediates involved. These insights present a modular and powerful strategy to access versatilely functionalized allyl-containing skeletons from readily available and stable carboxylic acids.

ACS Catalysis published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C7H13ClNNaO5S, Application In Synthesis of 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Huang, Weichen published the artcileCobalt-Catalyzed Asymmetric Cross-Coupling Reaction of Fluorinated Secondary Benzyl Bromides with Lithium Aryl Boronates/ZnBr₂, Recommanded Product: Cobalt(II) dibromo(1,2-dimethoxyethane), the publication is Organic Letters (2020), 22(11), 4327-4332, database is CAplus and MEDLINE.

A cobalt-catalyzed asym. cross-coupling of α-bromo-α-fluorotoluene derivatives with a variety of aryl zincates derived from lithium aryl Bu pinacol boronates and ZnBr₂ under mild reaction conditions was described. In addition to mild reaction conditions, another advantage includes the compatibility of various common functional groups such as fluoride, chloride, bromide, cyano, or ester groups. Furthermore, this protocol was successfully applied to the enantioselective synthesis of three fluorinated derivatives of biol. active compounds or drug mols.

Organic Letters published new progress about 18346-57-1. 18346-57-1 belongs to bromides-buliding-blocks, auxiliary class Cobalt, name is Cobalt(II) dibromo(1,2-dimethoxyethane), and the molecular formula is C4H10Br2CoO2, Recommanded Product: Cobalt(II) dibromo(1,2-dimethoxyethane).

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Cheng, Cang published the artcileEnantioselective synthesis of quaternary 3,4-dihydroisoquinolinones via Heck carbonylation reactions: development and application to the synthesis of Minalrestat analogues, Application In Synthesis of 76283-09-5, the publication is Chemical Science (2019), 10(42), 9853-9858, database is CAplus and MEDLINE.

Minalrestat and its analogs represent structurally novel aldose reductase inhibitors, and the asym. synthesis of such pharmaceutically privileged mols. has not been reported yet. We have developed a palladium-catalyzed enantioselective intramol. carbonylative Heck reaction by using formate esters as the source of CO, which represents the first enantioselective synthesis of quaternary 3,4-dihydroisoquinolines. The reaction provides a facile and efficient method for the synthesis of enantiopure nitrogen-containing heterocyclic compounds bearing an all-carbon quaternary stereocenter. The reaction has been successfully applied to the first asym. synthesis of Minalrestat analogs.

Chemical Science published new progress about 76283-09-5. 76283-09-5 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzyl bromide,Benzene, name is 4-Bromo-1-(bromomethyl)-2-fluorobenzene, and the molecular formula is C7H5Br2F, Application In Synthesis of 76283-09-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary