Divergent Access to Seven/Five-Membered Rings Based on [1,6]-Hydride Shift/Cyclization Process was written by Hoshino, Daiki;Mori, Keiji. And the article was included in Organic Letters in 2021.Recommanded Product: 61150-57-0 This article mentions the following:
A divergent access to seven/five-membered rings based on a [1,6]-hydride shift/cyclization process from benzylidenemalonate with an o-alkoxymethyl group was achieved. Whereas Yb(OTf)3 afforded benzoxepines I [R = Me, Ph, 4-MeC6H4, 4-ClC6H4; R1 = H, Me; R2 = H, Me, MeO, F; R3 = H, Me, MeO, F; R2R3 = CH=CH-CH=CH] selectively and indanes II [R4 = H, Me; R5 = H, MeO; R6 = H, Me, MeO, F] were the main products when Sc(OTf)3 was employed. In the experiment, the researchers used many compounds, for example, 2-Bromo-4-fluorobenzylbromide (cas: 61150-57-0Recommanded Product: 61150-57-0).
2-Bromo-4-fluorobenzylbromide (cas: 61150-57-0) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 61150-57-0
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary