Lee, Ikchoon et al. published their research in Journal of Physical Organic Chemistry in 1993 | CAS: 83902-02-7

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.HPLC of Formula: 83902-02-7

Determination of reactivity by molecular orbital theory. Part 84. Theoretical studies of the effects of ortho-methyl substitution on SN1 and SN2 processes at primary and secondary benzylic carbons was written by Lee, Ikchoon;Kim, Nam Doo;Kim, Chang Kon. And the article was included in Journal of Physical Organic Chemistry in 1993.HPLC of Formula: 83902-02-7 This article mentions the following:

The effects of o-Me substitution on the transition-state (TS) structure and reactivity of SN1 and SN2 processes were investigated for primary and secondary benzyl (α-tert-butyl) derivatives MO theor. using the AM1 method. The o-Me groups have both stabilizing (by electron donation) and destabilizing (steric) effects on the SN2 TS; the former prevails for the primary whereas the latter effects becomes dominant for the secondary compounds In contrast, complex interplay of the two effects are operative in the SN1 TS of both primary and secondary derivatives leading to the reactivity order which is consistent with that observed by solvolytic experiments, o,o’-dimethyl < H < o-Me. The bond length-reactivity rule applies only for the primary benzyl SN2 series for which steric effects are insignificant. For reactions of benzyl derivatives is general the coplanarity between the carbenium sp2 center and the benzene ring, π-σc-x*, is most important in stabilizing TS structure for which other structural requirements may be relaxed. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7HPLC of Formula: 83902-02-7).

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.HPLC of Formula: 83902-02-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary