Rates and regioselectivities of the palladium-catalyzed ethynylation of substituted bromo- and dibromobenzenes was written by Singh, Rina;Just, George. And the article was included in Journal of Organic Chemistry in 1989.Category: bromides-buliding-blocks This article mentions the following:
The Pd(0)/Cu2Br2-catalyzed ethynylation of 1,2-dibromo-4-nitro- and 1,2-dibromo-3-nitrobenzenes provide rapidly the product in which the bromine para or ortho to the nitro group is displaced, whereas the corresponding dibromoacetamidobenzenes provide the product of meta displacement slowly. Investigation of the rates of a series of p-substituted bromobenzenes indicates that the reaction is zero-order with respect to the heptyne and bromobenzene concentration, with a Hammett ρ value of 2.8. In the experiment, the researchers used many compounds, for example, 3,4-Dibromoaniline (cas: 615-55-4Category: bromides-buliding-blocks).
3,4-Dibromoaniline (cas: 615-55-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary