8-Aminoquinolines as anticoccidials – part III was written by Armer, Richard E.;Barlow, Jacqueline S.;Chopra, Narinder;Dutton, Christopher J.;Greenway, David H. J.;Greenwood, Sean D. W.;Lad, Nita;Shaw, Jonothan;Thompson, Adrian P.;Thong, Kam-Wah;Tommasini, Ivan. And the article was included in Bioorganic & Medicinal Chemistry Letters in 1999.Application In Synthesis of N-(5-Bromopentyl)phthalimide This article mentions the following:
Analogs of the antimalarial pentaquine I in which the nature of the side-chain on the 8-amino position was varied, were prepared and evaluated for anticoccidial activity both in vitro and in vivo. Specifically, both the inter-nitrogen distance and the nature of the terminal amino group were investigated. Novel analogs of equal or improved efficacy in vitro and in vivo to pentaquine were discovered. In the experiment, the researchers used many compounds, for example, N-(5-Bromopentyl)phthalimide (cas: 954-81-4Application In Synthesis of N-(5-Bromopentyl)phthalimide).
N-(5-Bromopentyl)phthalimide (cas: 954-81-4) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application In Synthesis of N-(5-Bromopentyl)phthalimide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary