Nickel-Catalyzed Oxidative Decarboxylative Annulation for the Synthesis of Heterocycle-Containing Phenanthridinones was written by Honeycutt, Aaron P.;Hoover, Jessica M.. And the article was included in Organic Letters in 2018.Related Products of 29241-66-5 This article mentions the following:
A nickel-catalyzed oxidative decarboxylative annulation reaction of simple benzamides and (hetero)aromatic carboxylates has been developed. This reaction provides access to a large array of phenanthridinones, e.g. I, and their heterocyclic analogs, highlighting the utility and versatility of oxidative decarboxylative coupling strategies for C-C bond formation. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-fluoronicotinic acid (cas: 29241-66-5Related Products of 29241-66-5).
5-Bromo-2-fluoronicotinic acid (cas: 29241-66-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Related Products of 29241-66-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary