Practical synthesis of some novel unsymmetrical 1,3-dialkylpyrimidine derivatives at room temperature was written by Khalafi-Nezhad, Ali;Zare, Abdolkarim;Parhami, Abolfath;Rad, Mohammad N. Soltani. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2006.Quality Control of N-(5-Bromopentyl)phthalimide This article mentions the following:
The efficient synthesis of some novel unsym. 1,3-dialkylpyrimidines is described. N(3)-Alkylation of N(1)-substituted pyrimidine derivatives with various functionalized alkyl halides in the presence of catalytic amounts of tetrabutylammonium bromide (TBAB) and Cs2CO3 in MeCN affords the title compounds The reactions proceed at room temperature, and the products are obtained in good to excellent yields. In the experiment, the researchers used many compounds, for example, N-(5-Bromopentyl)phthalimide (cas: 954-81-4Quality Control of N-(5-Bromopentyl)phthalimide).
N-(5-Bromopentyl)phthalimide (cas: 954-81-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Quality Control of N-(5-Bromopentyl)phthalimide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary