Synthesis of UK-78282 was written by Liang, Xizhou;Da, Shijun;Li, Ying. And the article was included in Zhongguo Yiyao Gongye Zazhi in 2005.Related Products of 57293-19-3 This article mentions the following:
UK-78282 [i.e., 4-[(diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]piperidine] a novel potassium channel blocker (no data), was synthesized from 4-methoxycinnamic acid by reduction and bromination to give 3-(4-methoxyphenyl)-1-bromopropane, which subjected to condensation with Et piperidine-4-carboxylate followed by reduction and etherification by diphenylmethanol. The overall yield was 58%. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Related Products of 57293-19-3).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Related Products of 57293-19-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary