Reactions of toluic acids and their derivatives with the system SF4-HF-Br2 was written by Madzhumder, U.;Kunshenko, B. V.;Yagupol’skii, L. M.. And the article was included in Ukrainskii Khimicheskii Zhurnal (Russian Edition) in 1998.Name: 1-Bromo-2-methyl-3-(trifluoromethyl)benzene This article mentions the following:
Reaction of toluic acid and its derivatives with sulfur tetrafluoride in anhydrous hydrogen fluoride in the presence of a halogenating agent has been studied, and it has been shown that in the presence of bromine in the system SF4-HF-Br2 yields of trifluoromethyl derivatives are abruptly increased. In these cases, the products contain from 1-3 atoms of bromine in the benzene ring. In the experiment, the researchers used many compounds, for example, 1-Bromo-2-methyl-3-(trifluoromethyl)benzene (cas: 69902-83-6Name: 1-Bromo-2-methyl-3-(trifluoromethyl)benzene).
1-Bromo-2-methyl-3-(trifluoromethyl)benzene (cas: 69902-83-6) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Name: 1-Bromo-2-methyl-3-(trifluoromethyl)benzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary