Effect of structural factors and solvent nature in bromination of anilines was written by Bagmanov, B. T.. And the article was included in Russian Journal of Applied Chemistry in 2009.Category: bromides-buliding-blocks This article mentions the following:
Electrophilic bromination of anilines containing various ortho-, meta-, and para-substituents in the aromatic ring was studied. The optimal conditions for the synthesis of mono-, di-, tri-, and tetrabrominated anilines and brominated analog of Aniline Black were found. In the experiment, the researchers used many compounds, for example, 4-Amino-3-bromophenol (cas: 74440-80-5Category: bromides-buliding-blocks).
4-Amino-3-bromophenol (cas: 74440-80-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary