Direct Primary Amination of Alkylmetals with NH-Oxaziridine was written by Behnke, Nicole Erin;Kielawa, Russell;Kwon, Doo-Hyun;Ess, Daniel H.;Kurti, Laszlo. And the article was included in Organic Letters in 2018.Product Details of 57293-19-3 This article mentions the following:
A method for the primary electrophilic amination of primary, secondary, and tertiary organometallic substrates from a bench-stable NH-oxaziridine reagent is described. This facile and highly chemoselective transformation occurs at ambient temperature and without transition metal catalysts or purification by column chromatog. to provide alkylamine products in a single step. D. functional theory (DFT) calculations revealed that, despite the basicity of alkylmetals, the direct NH-transfer pathway is favored over proton and O-transfer. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Product Details of 57293-19-3).
1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Product Details of 57293-19-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary