Development of novel Gemini-cholesterol analogues for retinoid-related orphan receptors was written by Gomez-Bouzo, Uxia;Fall, Alioune;Osz, Judit;Fall, Yagamare;Rochel, Natacha;Santalla, Hugo. And the article was included in Organic Chemistry Frontiers in 2022.Related Products of 28322-40-9 This article mentions the following:
Retinoic-acid-related Orphan Receptors (RORs) regulate the maintenance of the circadian rhythm and immune response among others and are involved in increasing numbers of pathologies including autoimmune diseases, cancer and neurol. disorders leading to huge interest in the development of ROR ligands. Here, the synthesis of six novel Gemini cholesterol analogs such as I and the binding mode of I to RORĪ³ was described. In the experiment, the researchers used many compounds, for example, Isopentyltriphenylphosphonium bromide (cas: 28322-40-9Related Products of 28322-40-9).
Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Related Products of 28322-40-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary