A diboronic acid ‘glucose cleft’ and a biscrown ether ‘metal sandwich’ are allosterically coupled was written by James, Tony D.;Shinkai, Seiji. And the article was included in Journal of the Chemical Society, Chemical Communications in 1995.Safety of 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane This article mentions the following:
Glucose is released from the diboronic acid ‘cleft’ I when a metal ‘sandwich’ is formed by two 15-crown-5 rings; the binding events are sensitively monitored by changes in the fluorescence intensity. In the experiment, the researchers used many compounds, for example, 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1Safety of 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane).
2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 166821-88-1) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Safety of 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary